ofloxacin has been researched along with Co-infection in 4 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The series is part of an ongoing randomised controlled trial assessing rechallenge dosing following TB-associated cutaneous ADR." | 2.77 | Multiple drug hypersensitivity reactions to anti-tuberculosis drugs: five cases in HIV-infected patients. ( Dheda, K; Lehloenya, RJ; Todd, G; Wallace, J, 2012) |
| "Cefazolin resistance was seen in 13." | 1.72 | Corynebacterium Keratitis: Pure Versus Mixed Infection and Antibiotic Susceptibility Patterns From Different Tertiary Eye Care Centers. ( Das, S; Gunasekaran, R; Mitra, S; Mohamed, A; Prajna, L; Prajna, NV; Sharma, S; Soni, T, 2022) |
| "Ofloxacin treatment failed to counter the bacterial proliferation in Pyn-STm coinfected mice." | 1.48 | Plasmodium-Salmonella Coinfection Induces Intense Inflammatory Response, Oxidative Stress, and Liver Damage: A Mice Model Study for Therapeutic Strategy. ( Maurya, AK; Mittal, S; Pal, A; Pandey, AK; Patel, DK; Singh, D; Tiwari, N, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soni, T | 1 |
| Gunasekaran, R | 1 |
| Das, S | 1 |
| Mitra, S | 1 |
| Prajna, NV | 1 |
| Prajna, L | 1 |
| Sharma, S | 1 |
| Mohamed, A | 1 |
| Patel, DK | 1 |
| Mittal, S | 1 |
| Tiwari, N | 1 |
| Maurya, AK | 1 |
| Singh, D | 1 |
| Pandey, AK | 1 |
| Pal, A | 1 |
| Van der Walt, M | 1 |
| Lancaster, J | 1 |
| Odendaal, R | 1 |
| Davis, JG | 1 |
| Shean, K | 1 |
| Farley, J | 1 |
| Lehloenya, RJ | 1 |
| Wallace, J | 1 |
| Todd, G | 1 |
| Dheda, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Leveraging mHealth to Enable and Adapt Community Health Worker Strategies to Improve TB/HIV Patient Outcomes in South Africa (LEAP-TB-SA) Trial[NCT04298905] | 200 participants (Anticipated) | Interventional | 2022-03-10 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for ofloxacin and Co-infection
| Article | Year |
|---|---|
Multiple drug hypersensitivity reactions to anti-tuberculosis drugs: five cases in HIV-infected patients.
Topics: Adult; Antitubercular Agents; Coinfection; Drug Eruptions; Drug Hypersensitivity; Edema; Eosinophili | 2012 |
3 other studies available for ofloxacin and Co-infection
| Article | Year |
|---|---|
Corynebacterium Keratitis: Pure Versus Mixed Infection and Antibiotic Susceptibility Patterns From Different Tertiary Eye Care Centers.
Topics: Anti-Bacterial Agents; Cefazolin; Ciprofloxacin; Coinfection; Corynebacterium; Eye Infections, Bacte | 2022 |
Plasmodium-Salmonella Coinfection Induces Intense Inflammatory Response, Oxidative Stress, and Liver Damage: A Mice Model Study for Therapeutic Strategy.
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Coinfection; Cytokines; Disease Models, Animal; Liver | 2018 |
Serious treatment related adverse drug reactions amongst anti-retroviral naïve MDR-TB patients.
Topics: Adult; Antitubercular Agents; Coinfection; Cycloserine; Drug Resistance, Multiple, Bacterial; Female | 2013 |