ofloxacin has been researched along with Clostridium Infections in 6 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Clostridium Infections: Infections with bacteria of the genus CLOSTRIDIUM and closely related CLOSTRIDIOIDES species.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The recent epidemic of Clostridium difficile infection (CDI) has been attributed largely to the REA strain group BI (aka NAP1/027)." | 1.37 | Susceptibility of hamsters to infection by historic and epidemic BI Clostridium difficile strains during daily administration of three fluoroquinolones. ( Gerding, DN; Johnson, S; Nagaro, K; Phillips, ST; Sambol, SP, 2011) |
| "Levofloxacin was used alone in three cases and in combination with another antibiotic in three other cases." | 1.31 | Clostridium difficile infection associated with levofloxacin treatment. ( Ozawa, TT; Valadez, T, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Phillips, ST | 1 |
| Nagaro, K | 1 |
| Sambol, SP | 1 |
| Johnson, S | 1 |
| Gerding, DN | 1 |
| Meessen-Pinard, M | 1 |
| Sekulovic, O | 1 |
| Fortier, LC | 1 |
| Gaynes, R | 1 |
| Rimland, D | 1 |
| Killum, E | 1 |
| Lowery, HK | 1 |
| Johnson, TM | 1 |
| Killgore, G | 1 |
| Tenover, FC | 1 |
| Khurana, A | 1 |
| Vinayek, N | 1 |
| Recco, RA | 1 |
| Go, ES | 1 |
| Zaman, MM | 1 |
| Tekaya, R | 1 |
| Saidane, O | 1 |
| Abdelmoula, L | 1 |
| Ben Hadj Yahia, C | 1 |
| Manamani, L | 1 |
| Chaabouni, L | 1 |
| Zouari, R | 1 |
| Ozawa, TT | 1 |
| Valadez, T | 1 |
6 other studies available for ofloxacin and Clostridium Infections
| Article | Year |
|---|---|
Susceptibility of hamsters to infection by historic and epidemic BI Clostridium difficile strains during daily administration of three fluoroquinolones.
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Clostridioides difficile; Clostridium | 2011 |
Evidence of in vivo prophage induction during Clostridium difficile infection.
Topics: Anti-Bacterial Agents; Aza Compounds; Base Sequence; Ciprofloxacin; Clostridioides difficile; Clostr | 2012 |
Outbreak of Clostridium difficile infection in a long-term care facility: association with gatifloxacin use.
Topics: Case-Control Studies; Clostridioides difficile; Clostridium Infections; Cross Infection; Diarrhea; D | 2004 |
The incidence of Clostridium difficile-associated and non-C. difficile-associated diarrhea after use of gatifloxacin and levofloxacin in an acute-care facility.
Topics: Clostridioides difficile; Clostridium Infections; Diarrhea; Emergency Medical Services; Fluoroquinol | 2004 |
[Clostridium clostridiiforme vertebral osteomyelitis].
Topics: Adult; Anti-Bacterial Agents; Ciprofloxacin; Clostridium; Clostridium Infections; Drug Therapy, Comb | 2008 |
Clostridium difficile infection associated with levofloxacin treatment.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Di | 2002 |