ofloxacin has been researched along with Chronic Disease in 156 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "5% levofloxacin, with and without eyelid scrub, in patients with chronic blepharoconjunctivitis (CBC)." | 9.14 | A prospective study determining the efficacy of topical 0.5% levofloxacin on bacterial flora of patients with chronic blepharoconjunctivitis. ( He, L; Kampik, A; Kreutzer, TC; Mino de Kaspar, H; Nentwich, MM; Ta, CN; Yactayo-Miranda, Y, 2009) |
| "The aim of this study was to confirm further the efficacy and safety of levofloxacin in patients with chronic bacterial prostatitis (CBP) in Europe." | 9.13 | Oral levofloxacin 500 mg once daily in the treatment of chronic bacterial prostatitis. ( Botto, H; Naber, KG; Roscher, K; Schaefer, V, 2008) |
| "To evaluate the clinical efficacy of the Chinese medicine Yiqigushen Capsule combined with levofloxacin on type III A prostatitis." | 9.13 | [Yiqigushen capsule combined with levofloxacin highly effective for type III A prostatitis]. ( Guo, DF; Wang, HP; Zhang, HZ, 2008) |
| "Ninety-six patients with chronic bacterial prostatitis (CBP) and evidence of infection were randomized to receive a 4-week oral course of either prulifloxacin (a new fluoroquinolone) 600 mg or levofloxacin 500 mg once daily." | 9.12 | Prulifloxacin versus levofloxacin in the treatment of chronic bacterial prostatitis: a prospective, randomized, double-blind trial. ( Barbone, F; De Maria, M; Giannarini, G; Manassero, F; Mogorovich, A; Morelli, G; Selli, C; Valent, F, 2007) |
| "To study the therapeutic efficacy of Longqingpian combined with Levofloxacin on Type IIIA prostatitis." | 9.12 | [Longqingpian combined with levofloxacin highly effective for type IIIA prostatitis]. ( Cai, X; Huang, YF; Shang, XJ; Teng, WH; Xu, H, 2007) |
| "This post hoc analysis of data from a previous randomized, blinded, multicenter, parallel, noninferiority study assessed the bacterial etiology, symptom resolution, and tolerability of severe acute bacterial exacerbation of chronic bronchitis (ABECB) patients treated with either levofloxacin 750 mg QD for 5 days or amoxicillin/clavulanate 875 mg/125 mg BID for 10 days." | 9.12 | Levofloxacin 750 mg QD for five days versus amoxicillin/clavulanate 875 mg/125 mg BID for ten days for treatment of acute bacterial exacerbation of chronic bronchitis: a post hoc analysis of data from severely ill patients. ( Ambrusz, ME; Fisher, AC; Grossman, RF; Kahn, JB; Khashab, MM, 2006) |
| "We compared baseline and post-therapy prostate specific antigen (PSA) in patients with chronic bacterial prostatitis who were treated with levofloxacin or ciprofloxacin." | 9.11 | Treatment of chronic bacterial prostatitis with levofloxacin and ciprofloxacin lowers serum prostate specific antigen. ( Kahn, JB; Schaeffer, AJ; Tennenberg, AM; Wu, SC, 2005) |
| "To demonstrate that 5 days of treatment with a new fluoroquinolone, gemifloxacin, is at least as effective as 7 days of treatment with levofloxacin in adult patients with acute exacerbation of chronic bronchitis (AECB)." | 9.11 | A randomized, double-blind study comparing 5 days oral gemifloxacin with 7 days oral levofloxacin in patients with acute exacerbation of chronic bronchitis. ( Fogarty, C; Fulambarker, A; Sethi, S, 2004) |
| "To compare the safety and efficacy of levofloxacin with that of ciprofloxacin for the treatment of chronic bacterial prostatitis." | 9.10 | Levofloxacin versus ciprofloxacin in the treatment of chronic bacterial prostatitis: a randomized double-blind multicenter study. ( Bundrick, W; Heron, SP; Kahn, JB; Ray, P; Schiff, WM; Tennenberg, AM; Wiesinger, BA; Wright, PA; Wu, SC; Zadeikis, N, 2003) |
| "To perform a Canadian multicenter randomized placebo-controlled trial to evaluate the safety and efficacy of 6 weeks of levofloxacin therapy compared with placebo in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)." | 9.10 | Levofloxacin for chronic prostatitis/chronic pelvic pain syndrome in men: a randomized placebo-controlled multicenter trial. ( Barkin, J; Brock, G; Casey, RW; Clark, J; Downey, J; Flax, S; Goldfarb, B; Nickel, JC; Palmer, BW; Patrick, AB; Pommerville, PJ; Steinhoff, G; Zadra, J, 2003) |
| "A randomized, double-blind, double-dummy, three-arm parallel design, multicentre study was conducted among adult patients with acute exacerbation of chronic bronchitis (AECB) in order to compare the efficacy and safety of two different doses of levofloxacin with cefuroxime axetil." | 9.09 | Levofloxacin versus cefuroxime axetil in the treatment of acute exacerbation of chronic bronchitis: results of a randomized, double-blind study. ( Dolmann, A; Fiss, E; Maesen, FP; Shah, PM; Vetter, N; Wesch, R, 1999) |
| "We conducted a prospective, randomized, open-label trial, comparing oral ofloxacin with intravenous imipenem-cilastatin for the treatment of chronic osteomyelitis in order to evaluate the efficacy and tolerance." | 9.09 | Oral ofloxacin versus parenteral imipenem-cilastatin in the treatment of osteomyelitis. ( Barberán, J; Borja, J; García-Barbal, J; Gomis, M; Khorrami, S; Sánchez, B, 1999) |
| "The efficacy and safety of three oral fluoroquinolones (lomefloxacin, levofloxacin, and ciprofloxacin) for the treatment of chronic osteomyelitis were analyzed." | 9.09 | Ciprofloxacin, lomefloxacin, or levofloxacin as treatment for chronic osteomyelitis. ( Greenberg, RN; Newman, MT; Pectol, RW; Shariaty, S, 2000) |
| "The objective of this randomized, double-blind study was to compare the clinical efficacy of levofloxacin at two different dosages with that of cefuroxime axetil in patients with acute purulent exacerbations of chronic bronchitis and, in particular, to assess the impact of the susceptibility to levofloxacin on the clinical findings." | 9.09 | Clinical effectiveness of levofloxacin in patients with acute purulent exacerbations of chronic bronchitis: the relationship with in-vitro activity. ( Davies, BI; Maesen, FP, 1999) |
| "Comparison of efficacy and safety of sparfloxacin vs ofloxacin for treatment of acute bacterial exacerbations of chronic bronchitis (ABECB)." | 9.08 | Sparfloxacin vs ofloxacin in the treatment of acute bacterial exacerbations of chronic bronchitis: a multicenter, double-blind, randomized, comparative study. Sparfloxacin Multicenter ABECB Study Group. ( Bensch, G; Chodosh, S; DeAbate, CA; Harper, L; Henry, D; Jubran, A; Talbot, GH; Tipping, D, 1998) |
| "In a double-blind study of 137 patients with exacerbation of chronic bronchitis and chronic obstructive lung disease, the efficacy and safety of ofloxacin was compared with that of trimethoprim-sulfamethoxazole (TMP/SMX)." | 9.07 | Double-blind comparative study of ofloxacin (Hoe 280) and trimethoprim-sulfamethoxazole in the treatment of patients with acute exacerbations of chronic bronchitis and chronic obstructive lung disease. ( Boye, NP; Gaustad, P, 1991) |
| "128 Patients (45 female, 83 male) with acute exacerbations of chronic bronchitis were treated with either cefuroxime axetil 2 x 500 mg/d (n = 65) or ofloxacin 2 x 200 mg/d for 7-8 days in a randomized controlled multicenter trial." | 9.07 | [Treatment of acute exacerbations of chronic bronchitis. Multicenter, randomized comparative study of cefuroxime axetil versus ofloxacin]. ( Kleckow, M, 1991) |
| "A multicentric study was conducted to evaluate the clinical efficacy and tolerance of ofloxacin in the treatment of chronic sinusitis and chronic otitis (CSOM) in outpatients." | 9.07 | Effectiveness and safety of ofloxacin in chronic otitis media and chronic sinusitis in adult outpatients. ( Cohen, B; Gehanno, P, 1993) |
| "The present study compared ofloxacin and erythromycin in a double-blind study with parallel groups for clinical efficacy and the number and severity of adverse reactions in patients treated in general practice for acute or chronic sinusitis." | 9.07 | Antibiotic treatment of sinusitis in general practice. A double-blind study comparing ofloxacin and erythromycin. ( Egede, F; Husfeldt, P; Nielsen, PB, 1993) |
| "The efficacy and tolerance of ofloxacin and doxycycline were compared in patients with lower respiratory tract infections." | 9.06 | An open randomised comparison of ofloxacin and doxycycline in lower respiratory tract infections. ( Harazim, H; Mittermayer, HP; Wimmer, J, 1987) |
| "In an open clinical trial, out-patients with respiratory tract infections were given 200 mg ofloxacin b." | 9.06 | [Respiratory tract infections--clinical results with ofloxacin]. ( Knothe, H; Shah, PM, 1986) |
| "In a double-blind study in 84 patients with chronic bronchitis and purulent exacerbations, ofloxacin 200 mg b." | 9.06 | A comparative study of ofloxacin and pivmecillinam in acute exacerbations of chronic bronchitis. ( Egede, F; Kristensen, I, 1990) |
| "The efficacy and safety of ofloxacin 400 mg once daily and amoxycillin/clavulanic acid 500/125 mg three times daily were compared in a double-blind manner in patients with an acute exacerbation of chronic bronchitis." | 9.06 | A double-blind comparison of low-dose ofloxacin and amoxycillin/clavulanic acid in acute exacerbations of chronic bronchitis. ( Beumer, HM; Hoepelman, IM; Möllers, MJ; Overbeek, BP; Rademaker, CM; Rozenberg-Arska, M; Sips, AP; Verhoef, J, 1990) |
| "192 patients, most of them ambulatory, with acute exacerbation of chronic bronchitis were treated with 10- to 14-day courses of oral ofloxacin receiving 400 mg once daily or doxycycline first 200 mg and then 100 mg once daily in this randomized observer-blinded multicentre study." | 9.06 | Oral ofloxacin once daily and doxycycline in the treatment of acute exacerbations of chronic bronchitis. ( Ammälä, K; Aro, A; Backman, R; Keistinen, T; Lehtipuu, AL; Punakivi, L; Saarelainen, P; Veneskoski, T; Vilkka, V, 1990) |
| "The aim of this prospective observational study was to present relevant data on the efficacy and safety of levofloxacin in the treatment of chronic bacterial prostatitis (NIH-II) in the daily clinical routine of urologists in their practices." | 7.77 | [Practice management of chronic bacterial prostatitis with levofloxacin]. ( Naber, KG; Roscher, K; Wagenlehner, F, 2011) |
| "Studies of acute exacerbations of chronic bronchitis (EXCB) included in the approval documents of levofloxacin (LVF) were reviewed in light of the good conditions of use defined by the French marketing approval and the AFSSAPS recommendations." | 7.72 | [Efficacy of levofloxacin in the treatment of acute exacerbation of chronic bronchitis in patients with risk factors]. ( Brumpt, I; Veyssier, P; Zuck, P, 2004) |
| "Two different oral ofloxacin regimens, a daily single-dose regimen with 200 mg (Regimen I) and an every-two-week multidose regimen with 3 x 200 mg/day (Regimen II) was compared as to the efficacy in controlling repeated acute exacerbations of chronic respiratory tract infections." | 7.69 | Daily single-dose regimen and alternate-two-week triple-dose/day regimen of oral ofloxacin for the prophylaxis and control of exacerbations of chronic respiratory tract infections. ( Motomiya, M; Nukiwa, T; Oizumi, K; Watanabe, A, 1995) |
| "The clinical efficacy and the safety of ofloxacin in lower respiratory tract infections were evaluated by 42 research groups in Japan." | 7.67 | Clinical evaluation of ofloxacin in lower respiratory tract infections. ( Kobayashi, H, 1986) |
| "After ascertaining the bacterial spectrum in 210 patients with Otitis media acuta, Otitis media chronica mesotympanalis and Otitis media chronica epitympanalis, the clinical efficacy of oral therapy with ofloxacin in 40 patients from each of these groups was assessed." | 7.67 | Ofloxacin in oral chemotherapy of acute and chronic otitis media. ( Lenarz, T, 1986) |
| "After ascertaining the bacterial spectrum in 105 patients with Otitis media acutissima, Otitis media chronica mesotympanalis and Otitis media chronica epitympanalis, the efficacy of oral therapy with ofloxacin in five patients from each of these groups was assessed." | 7.67 | [Ofloxacin in the conservative therapy of acute and chronic otitis media--a preliminary clinical report of experiences]. ( Lenarz, T, 1986) |
| "Levofloxacin was the most potent antibiotic against all cystic fibrosis isolates tested, with MIC(90)s ranging from 8 to 32 microg/ml." | 5.36 | In vitro pharmacodynamics of levofloxacin and other aerosolized antibiotics under multiple conditions relevant to chronic pulmonary infection in cystic fibrosis. ( Burns, JL; Dudley, MN; Griffith, DC; King, P; Lomovskaya, O, 2010) |
| "Levofloxacin was given to each patient at a dose of 300 mg or 400 mg a day for 7-14 days (average 12." | 5.28 | [Clinical study of levofloxacin (DR-3355) on uro-genital infections--with special reference to usefulness for chronic prostatitis]. ( Horiba, M; Suzuki, K, 1992) |
| "We obtained NIH-CPSI and IIEF-5 scores from 132 chronic prostatitis patients with ED and divided the patients into a control (n = 70) and a treatment group (n = 62), the former treated with oral levofloxacin 0." | 5.16 | [Efficacy of compound Xuanju capsule in the treatment of chronic prostatitis with erectile dysfunction]. ( Chao, WF; Huang, XK; Liang, P; Liu, JW; Wang, L; Wang, QT; Yang, H; Yang, W; Zhou, P, 2012) |
| "5% levofloxacin, with and without eyelid scrub, in patients with chronic blepharoconjunctivitis (CBC)." | 5.14 | A prospective study determining the efficacy of topical 0.5% levofloxacin on bacterial flora of patients with chronic blepharoconjunctivitis. ( He, L; Kampik, A; Kreutzer, TC; Mino de Kaspar, H; Nentwich, MM; Ta, CN; Yactayo-Miranda, Y, 2009) |
| "To evaluate the clinical efficacy of the Chinese medicine Yiqigushen Capsule combined with levofloxacin on type III A prostatitis." | 5.13 | [Yiqigushen capsule combined with levofloxacin highly effective for type III A prostatitis]. ( Guo, DF; Wang, HP; Zhang, HZ, 2008) |
| "The aim of this study was to confirm further the efficacy and safety of levofloxacin in patients with chronic bacterial prostatitis (CBP) in Europe." | 5.13 | Oral levofloxacin 500 mg once daily in the treatment of chronic bacterial prostatitis. ( Botto, H; Naber, KG; Roscher, K; Schaefer, V, 2008) |
| "This post hoc analysis of data from a previous randomized, blinded, multicenter, parallel, noninferiority study assessed the bacterial etiology, symptom resolution, and tolerability of severe acute bacterial exacerbation of chronic bronchitis (ABECB) patients treated with either levofloxacin 750 mg QD for 5 days or amoxicillin/clavulanate 875 mg/125 mg BID for 10 days." | 5.12 | Levofloxacin 750 mg QD for five days versus amoxicillin/clavulanate 875 mg/125 mg BID for ten days for treatment of acute bacterial exacerbation of chronic bronchitis: a post hoc analysis of data from severely ill patients. ( Ambrusz, ME; Fisher, AC; Grossman, RF; Kahn, JB; Khashab, MM, 2006) |
| "To study the therapeutic efficacy of Longqingpian combined with Levofloxacin on Type IIIA prostatitis." | 5.12 | [Longqingpian combined with levofloxacin highly effective for type IIIA prostatitis]. ( Cai, X; Huang, YF; Shang, XJ; Teng, WH; Xu, H, 2007) |
| "Ninety-six patients with chronic bacterial prostatitis (CBP) and evidence of infection were randomized to receive a 4-week oral course of either prulifloxacin (a new fluoroquinolone) 600 mg or levofloxacin 500 mg once daily." | 5.12 | Prulifloxacin versus levofloxacin in the treatment of chronic bacterial prostatitis: a prospective, randomized, double-blind trial. ( Barbone, F; De Maria, M; Giannarini, G; Manassero, F; Mogorovich, A; Morelli, G; Selli, C; Valent, F, 2007) |
| "We compared baseline and post-therapy prostate specific antigen (PSA) in patients with chronic bacterial prostatitis who were treated with levofloxacin or ciprofloxacin." | 5.11 | Treatment of chronic bacterial prostatitis with levofloxacin and ciprofloxacin lowers serum prostate specific antigen. ( Kahn, JB; Schaeffer, AJ; Tennenberg, AM; Wu, SC, 2005) |
| "To demonstrate that 5 days of treatment with a new fluoroquinolone, gemifloxacin, is at least as effective as 7 days of treatment with levofloxacin in adult patients with acute exacerbation of chronic bronchitis (AECB)." | 5.11 | A randomized, double-blind study comparing 5 days oral gemifloxacin with 7 days oral levofloxacin in patients with acute exacerbation of chronic bronchitis. ( Fogarty, C; Fulambarker, A; Sethi, S, 2004) |
| "To compare the safety and efficacy of levofloxacin with that of ciprofloxacin for the treatment of chronic bacterial prostatitis." | 5.10 | Levofloxacin versus ciprofloxacin in the treatment of chronic bacterial prostatitis: a randomized double-blind multicenter study. ( Bundrick, W; Heron, SP; Kahn, JB; Ray, P; Schiff, WM; Tennenberg, AM; Wiesinger, BA; Wright, PA; Wu, SC; Zadeikis, N, 2003) |
| "To perform a Canadian multicenter randomized placebo-controlled trial to evaluate the safety and efficacy of 6 weeks of levofloxacin therapy compared with placebo in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)." | 5.10 | Levofloxacin for chronic prostatitis/chronic pelvic pain syndrome in men: a randomized placebo-controlled multicenter trial. ( Barkin, J; Brock, G; Casey, RW; Clark, J; Downey, J; Flax, S; Goldfarb, B; Nickel, JC; Palmer, BW; Patrick, AB; Pommerville, PJ; Steinhoff, G; Zadra, J, 2003) |
| "The objective of this randomized, double-blind study was to compare the clinical efficacy of levofloxacin at two different dosages with that of cefuroxime axetil in patients with acute purulent exacerbations of chronic bronchitis and, in particular, to assess the impact of the susceptibility to levofloxacin on the clinical findings." | 5.09 | Clinical effectiveness of levofloxacin in patients with acute purulent exacerbations of chronic bronchitis: the relationship with in-vitro activity. ( Davies, BI; Maesen, FP, 1999) |
| "We conducted a prospective, randomized, open-label trial, comparing oral ofloxacin with intravenous imipenem-cilastatin for the treatment of chronic osteomyelitis in order to evaluate the efficacy and tolerance." | 5.09 | Oral ofloxacin versus parenteral imipenem-cilastatin in the treatment of osteomyelitis. ( Barberán, J; Borja, J; García-Barbal, J; Gomis, M; Khorrami, S; Sánchez, B, 1999) |
| "The efficacy and safety of three oral fluoroquinolones (lomefloxacin, levofloxacin, and ciprofloxacin) for the treatment of chronic osteomyelitis were analyzed." | 5.09 | Ciprofloxacin, lomefloxacin, or levofloxacin as treatment for chronic osteomyelitis. ( Greenberg, RN; Newman, MT; Pectol, RW; Shariaty, S, 2000) |
| "A randomized, double-blind, double-dummy, three-arm parallel design, multicentre study was conducted among adult patients with acute exacerbation of chronic bronchitis (AECB) in order to compare the efficacy and safety of two different doses of levofloxacin with cefuroxime axetil." | 5.09 | Levofloxacin versus cefuroxime axetil in the treatment of acute exacerbation of chronic bronchitis: results of a randomized, double-blind study. ( Dolmann, A; Fiss, E; Maesen, FP; Shah, PM; Vetter, N; Wesch, R, 1999) |
| "Comparison of efficacy and safety of sparfloxacin vs ofloxacin for treatment of acute bacterial exacerbations of chronic bronchitis (ABECB)." | 5.08 | Sparfloxacin vs ofloxacin in the treatment of acute bacterial exacerbations of chronic bronchitis: a multicenter, double-blind, randomized, comparative study. Sparfloxacin Multicenter ABECB Study Group. ( Bensch, G; Chodosh, S; DeAbate, CA; Harper, L; Henry, D; Jubran, A; Talbot, GH; Tipping, D, 1998) |
| "Fifteen patients with various forms of pyelonephritis and chronic cystitis were treated with ofloxacin." | 5.08 | [Comprehensive treatment with ofloxacin in pyo-inflammatory urologic diseases]. ( Pytel', IuA; Volkova, VS, 1996) |
| "Ofloxacin was used in the treatment of 15 patients (12 with pneumonia and 3 with aggravated chronic bronchitis)." | 5.08 | [Stepdown ofloxacin therapy in bronchopulmonary diseases]. ( Lenkova, NI; Makarova, OV; Nonikov, VE; Ritchik, LA, 1996) |
| "A multicentric study was conducted to evaluate the clinical efficacy and tolerance of ofloxacin in the treatment of chronic sinusitis and chronic otitis (CSOM) in outpatients." | 5.07 | Effectiveness and safety of ofloxacin in chronic otitis media and chronic sinusitis in adult outpatients. ( Cohen, B; Gehanno, P, 1993) |
| "Two different oral ofloxacin regimens, daily single-dose treatment with 200 mg (Regimen I) and every two week multidose treatment with 3 x 200 mg/day (Regimen II), were compared to evaluate the efficacy of quinolone regimens in controlling acute exacerbations of chronic respiratory tract infections." | 5.07 | Once daily versus every two week multidose ofloxacin in patients with acute exacerbations of chronic respiratory disease. ( Watanabe, A, 1991) |
| "In a double-blind study of 137 patients with exacerbation of chronic bronchitis and chronic obstructive lung disease, the efficacy and safety of ofloxacin was compared with that of trimethoprim-sulfamethoxazole (TMP/SMX)." | 5.07 | Double-blind comparative study of ofloxacin (Hoe 280) and trimethoprim-sulfamethoxazole in the treatment of patients with acute exacerbations of chronic bronchitis and chronic obstructive lung disease. ( Boye, NP; Gaustad, P, 1991) |
| "The present study compared ofloxacin and erythromycin in a double-blind study with parallel groups for clinical efficacy and the number and severity of adverse reactions in patients treated in general practice for acute or chronic sinusitis." | 5.07 | Antibiotic treatment of sinusitis in general practice. A double-blind study comparing ofloxacin and erythromycin. ( Egede, F; Husfeldt, P; Nielsen, PB, 1993) |
| "128 Patients (45 female, 83 male) with acute exacerbations of chronic bronchitis were treated with either cefuroxime axetil 2 x 500 mg/d (n = 65) or ofloxacin 2 x 200 mg/d for 7-8 days in a randomized controlled multicenter trial." | 5.07 | [Treatment of acute exacerbations of chronic bronchitis. Multicenter, randomized comparative study of cefuroxime axetil versus ofloxacin]. ( Kleckow, M, 1991) |
| "The efficacy and safety of ofloxacin 400 mg once daily and amoxycillin/clavulanic acid 500/125 mg three times daily were compared in a double-blind manner in patients with an acute exacerbation of chronic bronchitis." | 5.06 | A double-blind comparison of low-dose ofloxacin and amoxycillin/clavulanic acid in acute exacerbations of chronic bronchitis. ( Beumer, HM; Hoepelman, IM; Möllers, MJ; Overbeek, BP; Rademaker, CM; Rozenberg-Arska, M; Sips, AP; Verhoef, J, 1990) |
| "Ofloxacin is highly active against common respiratory pathogens including Haemophilus influenzae and Branhamella catarrhalis and has clinically applicable activity against Streptococcus pneumoniae, Staphylococcus aureus and Pseudomonas aeruginosa." | 5.06 | Overview of experience with ofloxacin in respiratory tract infection. ( Ball, P, 1990) |
| "In a double-blind study in 84 patients with chronic bronchitis and purulent exacerbations, ofloxacin 200 mg b." | 5.06 | A comparative study of ofloxacin and pivmecillinam in acute exacerbations of chronic bronchitis. ( Egede, F; Kristensen, I, 1990) |
| "192 patients, most of them ambulatory, with acute exacerbation of chronic bronchitis were treated with 10- to 14-day courses of oral ofloxacin receiving 400 mg once daily or doxycycline first 200 mg and then 100 mg once daily in this randomized observer-blinded multicentre study." | 5.06 | Oral ofloxacin once daily and doxycycline in the treatment of acute exacerbations of chronic bronchitis. ( Ammälä, K; Aro, A; Backman, R; Keistinen, T; Lehtipuu, AL; Punakivi, L; Saarelainen, P; Veneskoski, T; Vilkka, V, 1990) |
| "In an open clinical trial, out-patients with respiratory tract infections were given 200 mg ofloxacin b." | 5.06 | [Respiratory tract infections--clinical results with ofloxacin]. ( Knothe, H; Shah, PM, 1986) |
| "The efficacy and tolerance of ofloxacin and doxycycline were compared in patients with lower respiratory tract infections." | 5.06 | An open randomised comparison of ofloxacin and doxycycline in lower respiratory tract infections. ( Harazim, H; Mittermayer, HP; Wimmer, J, 1987) |
| " holarctica in a stem cell transplant recipient with chronic graft-versus-host disease who was receiving levofloxacin prophylaxis." | 3.79 | Treatment of tularemia in patient with chronic graft-versus-host disease. ( Kaufmann, M; Knabbe, C; Seibold, E; Splettstoesser, W; Weile, J, 2013) |
| "The aim of this prospective observational study was to present relevant data on the efficacy and safety of levofloxacin in the treatment of chronic bacterial prostatitis (NIH-II) in the daily clinical routine of urologists in their practices." | 3.77 | [Practice management of chronic bacterial prostatitis with levofloxacin]. ( Naber, KG; Roscher, K; Wagenlehner, F, 2011) |
| "Studies of acute exacerbations of chronic bronchitis (EXCB) included in the approval documents of levofloxacin (LVF) were reviewed in light of the good conditions of use defined by the French marketing approval and the AFSSAPS recommendations." | 3.72 | [Efficacy of levofloxacin in the treatment of acute exacerbation of chronic bronchitis in patients with risk factors]. ( Brumpt, I; Veyssier, P; Zuck, P, 2004) |
| "This study was conducted to evaluate the activity of levofloxacin in comparison with a range of antibacterial agents against recent isolates obtained consecutively from patients with community-acquired pneumonia (CAP) or acute exacerbation of chronic bronchitis (AECB) during the period 1995 to 1996." | 3.70 | Comparative in-vitro activity of levofloxacin against isolates of bacteria from adult patients with community-acquired lower respiratory tract infections. ( Ariza, H; Ascoli, M; Casellas, JM; Dolmann, A; Gilardoni, M; Goldberg, M; Ivanovic, S; Montero, JM; Orduna, M; Tome, G, 1999) |
| "Sixty outpatients at the age of 65 to 75 years with exacerbated chronic bronchitis were treated with antibiotics: amoxycillin/clavulanic acid (20 patients), cefaclor (20 patients) and ciprofloxacin (20 patients)." | 3.69 | [Treatment of lower respiratory tract infections in the elderly]. ( Belousov, IuB; Efremenkova, OV; Komarova, VP; Sokolov, AV; Tishchenkova, IF, 1997) |
| "Two different oral ofloxacin regimens, a daily single-dose regimen with 200 mg (Regimen I) and an every-two-week multidose regimen with 3 x 200 mg/day (Regimen II) was compared as to the efficacy in controlling repeated acute exacerbations of chronic respiratory tract infections." | 3.69 | Daily single-dose regimen and alternate-two-week triple-dose/day regimen of oral ofloxacin for the prophylaxis and control of exacerbations of chronic respiratory tract infections. ( Motomiya, M; Nukiwa, T; Oizumi, K; Watanabe, A, 1995) |
| "Simultaneous bronchial biopsy and serum samples were obtained from 14 patients after a single oral dose of 200 mg ofloxacin and from ten patients during the course of multiple dose oral treatment, (200 mg ofloxacin bd) for acute exacerbations of chronic bronchitis." | 3.68 | Bronchial penetration of ofloxacin after single and multiple oral dosage. ( Davey, PG; Precious, E; Winter, J, 1991) |
| "Ofloxacine (Tarivid-Hoechst) was used in 30 patients with infections of the respiratory system, including 12 with pneumonias, 18 with chronic bronchitis." | 3.68 | [Evaluation of the effectiveness of ofloxacin in the treatment of respiratory tract]. ( Chyrek-Borowska, S; Jakubicz, P; Siergiejko, Z, 1991) |
| "In order to determine the efficacy and safety of the new quinolone ofloxacin in the treatment of chronic lower respiratory disease, 674 patients (353 with chronic bronchitis, 212 with community-acquired pneumonia and 109 with hospital-acquired pneumonia) were treated with ofloxacin 200 mg twice a day." | 3.68 | Ofloxacin in lower respiratory tract infections. ( Petermann, W, 1991) |
| "After ascertaining the bacterial spectrum in 105 patients with Otitis media acutissima, Otitis media chronica mesotympanalis and Otitis media chronica epitympanalis, the efficacy of oral therapy with ofloxacin in five patients from each of these groups was assessed." | 3.67 | [Ofloxacin in the conservative therapy of acute and chronic otitis media--a preliminary clinical report of experiences]. ( Lenarz, T, 1986) |
| "The clinical efficacy and the safety of ofloxacin in lower respiratory tract infections were evaluated by 42 research groups in Japan." | 3.67 | Clinical evaluation of ofloxacin in lower respiratory tract infections. ( Kobayashi, H, 1986) |
| "After ascertaining the bacterial spectrum in 210 patients with Otitis media acuta, Otitis media chronica mesotympanalis and Otitis media chronica epitympanalis, the clinical efficacy of oral therapy with ofloxacin in 40 patients from each of these groups was assessed." | 3.67 | Ofloxacin in oral chemotherapy of acute and chronic otitis media. ( Lenarz, T, 1986) |
| " In the present study, the efficacy and safety of ofloxacin alone (OA) and the ofloxacin + dexamethasone combination (ODC) is compared by studying clinical cure rates and adverse drug reactions in patients with CSOM." | 2.80 | Efficacy and safety of ofloxacin and its combination with dexamethasone in chronic suppurative otitis media. A randomised, double blind, parallel group, comparative study. ( Jha, S; Mandavia, D; Panchasara, A; Singh, A; Tripathi, C, 2015) |
| "Sarcoidosis is a chronic granulomatous disease for which there are limited therapeutic options." | 2.78 | Oral antimycobacterial therapy in chronic cutaneous sarcoidosis: a randomized, single-masked, placebo-controlled study. ( Aboud, C; Algood, H; Boyd, AS; Braun, N; Burke, VE; Drake, WP; Isom, J; Kaminski, N; King, LE; Oswald-Richter, K; Pandit, KV; Richmond, BW; Taylor, T; Yu, C, 2013) |
| "Ofloxacin eardrops were effective in the initial treatment of active chronic suppurative otitis media." | 2.67 | Ofloxacin eardrop treatment for active chronic suppurative otitis media: prospective randomized study. ( Chau, PY; Hui, Y; Lau, SK; Wei, WI; Wong, S; Wong, SF; Yuen, PW, 1994) |
| "Ofloxacin was administered orally at a daily dosage of 300 mg and 600 mg in three divided doses for 14 days to 24 and 60 patients with chronic complicated urinary infections, respectively, in order to evaluate the therapeutic efficacy." | 2.67 | [Clinical evaluation of ofloxacin in the treatment of chronic complicated urinary tract infection]. ( Hisazumi, H; Kobashi, K; Koizumi, H; Motoi, I; Nagano, K; Nishino, A; Orito, M; Sawaki, M; Shyoda, R; Uchibayashi, T, 1990) |
| "Two cases of chronic, cavernous pulmonary tuberculosis with bacilli resistant to several drugs are presented." | 2.66 | [2 cases of drug-resistant pulmonary tuberculosis treated with ofloxacin]. ( Krakówka, P; Krasucka-Kluźniak, A, 1989) |
| "Ofloxacin kinetics were influenced by renal dysfunction encountered in patients with ascites." | 2.38 | Pharmacokinetics of fluoroquinolones in hepatic failure. ( Gaillot, J; Montay, G, 1990) |
| " Lead optimization resulted in the identification of potent compounds with improved oral bioavailability and reduced cardiac ion channel liability." | 1.40 | Novel N-linked aminopiperidine-based gyrase inhibitors with improved hERG and in vivo efficacy against Mycobacterium tuberculosis. ( Achar, V; Arora, U; Awasthy, D; Bharath, S; Bheemarao, U; Chinnapattu, M; Coulson, M; de Sousa, SM; Ganguly, S; Gaonkar, S; Ghosh, A; Hameed P, S; Hoffner, S; Humnabadkar, V; Kaur, P; Kumar K N, M; Kumar, CN; Madhavapeddi, P; Manjrekar, P; Menasinakai, S; Mukherjee, K; Nandishaiah, R; Narayan, C; Panduga, V; Patil, V; Puttur, J; Raichurkar, A; Ramya, VK; Reddy, J; Rudrapatana, S; Sambandamurthy, VK; Shanbhag, G; Sharma, S; Sharma, U; Shinde, V; Solapure, S; Waterson, D; Werngren, J, 2014) |
| "Levofloxacin treatment did not affect the cytokine mRNA level and nuclear factor-κB-dependent promoter activity." | 1.37 | Levofloxacin reduces inflammatory cytokine levels in human bronchial epithelia cells: implications for aerosol MP-376 (levofloxacin solution for inhalation) treatment of chronic pulmonary infections. ( Dudley, MN; Griffith, DC; Lomovskaya, O; Sabet, M; Tarazi, Z; Tsivkovskii, R, 2011) |
| "Bronchopulmonary sequestration is a rare malformation characterized by lung tissue fed by one or several aberrant systemic arteries." | 1.36 | [Persistent pleuropneumopathy in a young woman]. ( Abada, D; Aouina, H; Baccar, MA; Ben Amar, J; Bouacha, H; Dhahri, B; El Gharbi, L; Kilani, T; Saloua, S, 2010) |
| "Levofloxacin was the most potent antibiotic against all cystic fibrosis isolates tested, with MIC(90)s ranging from 8 to 32 microg/ml." | 1.36 | In vitro pharmacodynamics of levofloxacin and other aerosolized antibiotics under multiple conditions relevant to chronic pulmonary infection in cystic fibrosis. ( Burns, JL; Dudley, MN; Griffith, DC; King, P; Lomovskaya, O, 2010) |
| "Bacterial prostatitis is documented at a very low prevalence (7-13% of prostatitis overall considered) due to either reduced utilization of viral and bacteriological tests (Meares test, urethral swab, bacterial and viral PCR) or to the possibility that individual patients show a scarce expression of bacterial disease in biological fluids, because of intraglandular biofilm presence, with subsequent spreading of the sole plankton microrganisms." | 1.35 | [Chronic prostatitis and biofilm]. ( Bartoletti, R; Cai, T, 2009) |
| "Ofloxacin was susceptible on all isolates." | 1.32 | Bacteriology of chronic suppurative otitis media in congolese children. ( Muyunga, CK; Nyembue, DT; Sabue, MJ; Tshiswaka, JM, 2003) |
| "Encrusted cystitis is a type of severe cystitis, which progresses chronically and is characterized by excessively alkaline urine and calcifications within the bladder wall." | 1.32 | [Two cases of encrusted cystitis]. ( Arai, Y; Ichioka, K; Matsui, Y; Ohara, H; Terada, N; Terai, A; Yoshimura, K, 2004) |
| "We report a chronic case of pulmonary tuberculosis in a Malagasy citizen from Antsohihy (West of Madagascar), who was infected with a multi-drug resistant Mycobacterium bovis strain." | 1.32 | [A case of pulmonary multiresistant Mycobacterium bovis tuberculosis in Madagascar]. ( Andrianasolo, D; Ramarokoto, H; Ramaroson, F; Rasolofo Razanamparany, V; Rasolonavalona, T; Ratsimba, L; Razafitsiarovana, I; Vincent, V, 2003) |
| "25 mL in children with chronic suppurative otitis media and perforated tympanic membrane, with serial sampling of otorrhea and serum up to 8 hours after dosing and middle ear mucosa up to 2 hours after dosing." | 1.30 | Ofloxacin otic solution in patients with otitis media: an analysis of drug concentrations. ( Furuta, S; Katsuda, K; Kiyota, R; Miyazaki, Y; Nobori, T; Ohyama, M; Ueno, K, 1999) |
| "Ofloxacin treatment gave good result in reduction of otorrhea, regardless of the earlier treatment of chronic otitis media." | 1.30 | [Clinical success of treatment of chronic otitis media using topical and peroral administration of ofloxacin]. ( Dzelalija, B; Kovacić, M, 1999) |
| "Levofloxacin was given to each patient at a dose of 300 mg or 400 mg a day for 7-14 days (average 12." | 1.28 | [Clinical study of levofloxacin (DR-3355) on uro-genital infections--with special reference to usefulness for chronic prostatitis]. ( Horiba, M; Suzuki, K, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (10.90) | 18.7374 |
| 1990's | 69 (44.23) | 18.2507 |
| 2000's | 51 (32.69) | 29.6817 |
| 2010's | 15 (9.62) | 24.3611 |
| 2020's | 4 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Hameed P, S | 1 |
| Patil, V | 1 |
| Solapure, S | 1 |
| Sharma, U | 1 |
| Madhavapeddi, P | 1 |
| Raichurkar, A | 1 |
| Chinnapattu, M | 1 |
| Manjrekar, P | 1 |
| Shanbhag, G | 1 |
| Puttur, J | 1 |
| Shinde, V | 1 |
| Menasinakai, S | 1 |
| Rudrapatana, S | 1 |
| Achar, V | 1 |
| Awasthy, D | 1 |
| Nandishaiah, R | 1 |
| Humnabadkar, V | 1 |
| Ghosh, A | 1 |
| Narayan, C | 1 |
| Ramya, VK | 1 |
| Kaur, P | 1 |
| Sharma, S | 1 |
| Werngren, J | 1 |
| Hoffner, S | 1 |
| Panduga, V | 1 |
| Kumar, CN | 1 |
| Reddy, J | 1 |
| Kumar K N, M | 1 |
| Ganguly, S | 1 |
| Bharath, S | 1 |
| Bheemarao, U | 1 |
| Mukherjee, K | 1 |
| Arora, U | 1 |
| Gaonkar, S | 1 |
| Coulson, M | 1 |
| Waterson, D | 1 |
| Sambandamurthy, VK | 1 |
| de Sousa, SM | 1 |
| Ma, WJ | 1 |
| Wu, ZR | 1 |
| Yang, Q | 1 |
| Hu, HJ | 1 |
| Wang, JK | 1 |
| Shi, YJ | 1 |
| Li, FY | 1 |
| Cheng, NS | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 4 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Song, J | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 1 |
| Palomeque, E | 1 |
| Saud, N | 1 |
| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
| Lemoine, J | 1 |
| Li, X | 10 |
| Henson, MA | 1 |
| Unsihuay, D | 1 |
| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
| Kozhinov, AN | 1 |
| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
| Zin, NNINM | 1 |
| Mohamad, MN | 1 |
| Roslan, K | 1 |
| Abdul Wafi, S | 1 |
| Abdul Moin, NI | 1 |
| Alias, A | 1 |
| Zakaria, Y | 1 |
| Abu-Bakar, N | 1 |
| Naveed, A | 1 |
| Jilani, K | 1 |
| Siddique, AB | 1 |
| Akbar, M | 1 |
| Riaz, M | 1 |
| Mushtaq, Z | 1 |
| Sikandar, M | 1 |
| Ilyas, S | 1 |
| Bibi, I | 1 |
| Asghar, A | 1 |
| Rasool, G | 1 |
| Irfan, M | 1 |
| Li, XY | 1 |
| Zhao, S | 1 |
| Fan, XH | 1 |
| Chen, KP | 1 |
| Hua, W | 1 |
| Liu, ZM | 1 |
| Xue, XD | 1 |
| Zhou, B | 1 |
| Zhang, S | 2 |
| Xing, YL | 1 |
| Chen, MA | 1 |
| Sun, Y | 1 |
| Neradilek, MB | 1 |
| Wu, XT | 1 |
| Zhang, D | 2 |
| Huang, W | 1 |
| Cui, Y | 2 |
| Yang, QQ | 1 |
| Li, HW | 1 |
| Zhao, XQ | 1 |
| Hossein Rashidi, B | 1 |
| Tarafdari, A | 1 |
| Ghazimirsaeed, ST | 1 |
| Shahrokh Tehraninezhad, E | 1 |
| Keikha, F | 1 |
| Eslami, B | 1 |
| Ghazimirsaeed, SM | 1 |
| Jafarabadi, M | 1 |
| Silvani, Y | 1 |
| Lovita, AND | 1 |
| Maharani, A | 1 |
| Wiyasa, IWA | 1 |
| Sujuti, H | 1 |
| Ratnawati, R | 1 |
| Raras, TYM | 1 |
| Lemin, AS | 1 |
| Rahman, MM | 1 |
| Pangarah, CA | 1 |
| Kiyu, A | 1 |
| Zeng, C | 2 |
| Du, H | 1 |
| Lin, D | 1 |
| Jalan, D | 1 |
| Rubagumya, F | 1 |
| Hopman, WM | 1 |
| Vanderpuye, V | 1 |
| Lopes, G | 1 |
| Seruga, B | 1 |
| Booth, CM | 1 |
| Berry, S | 1 |
| Hammad, N | 1 |
| Sajo, EA | 1 |
| Okunade, KS | 1 |
| Olorunfemi, G | 1 |
| Rabiu, KA | 1 |
| Anorlu, RI | 1 |
| Xu, C | 2 |
| Xiang, Y | 1 |
| Xu, X | 1 |
| Zhou, L | 2 |
| Dong, X | 1 |
| Tang, S | 1 |
| Gao, XC | 1 |
| Wei, CH | 1 |
| Zhang, RG | 1 |
| Cai, Q | 1 |
| He, Y | 1 |
| Tong, F | 1 |
| Dong, JH | 1 |
| Wu, G | 1 |
| Dong, XR | 1 |
| Tang, X | 1 |
| Tao, F | 1 |
| Xiang, W | 1 |
| Zhao, Y | 3 |
| Jin, L | 1 |
| Tao, H | 1 |
| Lei, Y | 1 |
| Gan, H | 1 |
| Huang, Y | 1 |
| Chen, Y | 3 |
| Chen, L | 3 |
| Shan, A | 1 |
| Zhao, H | 2 |
| Wu, M | 2 |
| Ma, Q | 1 |
| Wang, J | 4 |
| Zhang, E | 1 |
| Zhang, J | 3 |
| Li, Y | 5 |
| Xue, F | 1 |
| Deng, L | 1 |
| Liu, L | 2 |
| Yan, Z | 2 |
| Wang, Y | 2 |
| Meng, J | 1 |
| Chen, G | 2 |
| Anastassiadou, M | 1 |
| Bernasconi, G | 1 |
| Brancato, A | 1 |
| Carrasco Cabrera, L | 1 |
| Greco, L | 1 |
| Jarrah, S | 1 |
| Kazocina, A | 1 |
| Leuschner, R | 1 |
| Magrans, JO | 1 |
| Miron, I | 1 |
| Nave, S | 1 |
| Pedersen, R | 1 |
| Reich, H | 1 |
| Rojas, A | 1 |
| Sacchi, A | 1 |
| Santos, M | 1 |
| Theobald, A | 1 |
| Vagenende, B | 1 |
| Verani, A | 1 |
| Du, L | 1 |
| Liu, X | 1 |
| Ren, Y | 1 |
| Li, J | 7 |
| Li, P | 1 |
| Jiao, Q | 1 |
| Meng, P | 1 |
| Wang, F | 2 |
| Wang, YS | 1 |
| Wang, C | 3 |
| Zhou, X | 2 |
| Wang, W | 1 |
| Wang, S | 2 |
| Hou, J | 1 |
| Zhang, A | 1 |
| Lv, B | 1 |
| Gao, C | 1 |
| Pang, D | 1 |
| Lu, K | 1 |
| Ahmad, NH | 1 |
| Wang, L | 2 |
| Zhu, J | 2 |
| Zhang, L | 2 |
| Zhuang, T | 1 |
| Tu, J | 1 |
| Zhao, Z | 1 |
| Qu, Y | 1 |
| Yao, H | 1 |
| Wang, X | 5 |
| Lee, DF | 1 |
| Shen, J | 3 |
| Wen, L | 1 |
| Huang, G | 2 |
| Xie, X | 1 |
| Zhao, Q | 1 |
| Hu, W | 1 |
| Zhang, Y | 4 |
| Wu, X | 1 |
| Lu, J | 2 |
| Li, M | 1 |
| Li, W | 2 |
| Wu, W | 1 |
| Du, F | 1 |
| Ji, H | 1 |
| Yang, X | 2 |
| Xu, Z | 1 |
| Wan, L | 1 |
| Wen, Q | 1 |
| Cho, CH | 1 |
| Zou, C | 1 |
| Xiao, Z | 1 |
| Liao, J | 1 |
| Su, X | 1 |
| Bi, Z | 1 |
| Su, Q | 1 |
| Huang, H | 1 |
| Wei, Y | 2 |
| Gao, Y | 2 |
| Na, KJ | 1 |
| Choi, H | 1 |
| Oh, HR | 1 |
| Kim, YH | 1 |
| Lee, SB | 1 |
| Jung, YJ | 1 |
| Koh, J | 1 |
| Park, S | 1 |
| Lee, HJ | 1 |
| Jeon, YK | 1 |
| Chung, DH | 1 |
| Paeng, JC | 1 |
| Park, IK | 1 |
| Kang, CH | 1 |
| Cheon, GJ | 1 |
| Kang, KW | 1 |
| Lee, DS | 1 |
| Kim, YT | 1 |
| Pajuelo-Lozano, N | 1 |
| Alcalá, S | 1 |
| Sainz, B | 1 |
| Perona, R | 1 |
| Sanchez-Perez, I | 1 |
| Logotheti, S | 1 |
| Marquardt, S | 1 |
| Gupta, SK | 1 |
| Richter, C | 1 |
| Edelhäuser, BAH | 1 |
| Engelmann, D | 1 |
| Brenmoehl, J | 1 |
| Söhnchen, C | 1 |
| Murr, N | 1 |
| Alpers, M | 1 |
| Singh, KP | 1 |
| Wolkenhauer, O | 1 |
| Heckl, D | 1 |
| Spitschak, A | 1 |
| Pützer, BM | 1 |
| Liao, Y | 1 |
| Cheng, J | 1 |
| Kong, X | 1 |
| Li, S | 1 |
| Zhang, M | 4 |
| Zhang, H | 1 |
| Yang, T | 2 |
| Dong, Y | 1 |
| Xu, Y | 1 |
| Yuan, Z | 1 |
| Cao, J | 1 |
| Zheng, Y | 1 |
| Luo, Z | 1 |
| Mei, Z | 1 |
| Yao, Y | 1 |
| Liu, Z | 3 |
| Liang, C | 1 |
| Yang, H | 2 |
| Song, Y | 1 |
| Yu, K | 1 |
| Zhu, C | 1 |
| Huang, Z | 1 |
| Qian, J | 1 |
| Ge, J | 1 |
| Hu, J | 2 |
| Wang, H | 2 |
| Liu, Y | 4 |
| Mi, Y | 1 |
| Kong, H | 1 |
| Xi, D | 1 |
| Yan, W | 1 |
| Luo, X | 1 |
| Ning, Q | 1 |
| Chang, X | 2 |
| Zhang, T | 2 |
| Wang, Q | 2 |
| Rathore, MG | 1 |
| Reddy, K | 1 |
| Chen, H | 1 |
| Shin, SH | 1 |
| Ma, WY | 1 |
| Bode, AM | 1 |
| Dong, Z | 1 |
| Mu, W | 1 |
| Liu, C | 3 |
| Gao, F | 1 |
| Qi, Y | 1 |
| Lu, H | 1 |
| Zhang, X | 4 |
| Cai, X | 2 |
| Ji, RY | 1 |
| Hou, Y | 3 |
| Tian, J | 2 |
| Shi, Y | 1 |
| Ying, S | 1 |
| Tan, M | 1 |
| Feng, G | 1 |
| Kuang, Y | 1 |
| Chen, D | 1 |
| Wu, D | 3 |
| Zhu, ZQ | 1 |
| Tang, HX | 1 |
| Shi, ZE | 1 |
| Kang, J | 1 |
| Liu, Q | 1 |
| Qi, J | 2 |
| Mu, J | 1 |
| Cong, Z | 1 |
| Chen, S | 2 |
| Fu, D | 1 |
| Li, Z | 2 |
| Celestrin, CP | 1 |
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| Saad, MJA | 1 |
| Oliveira, AG | 1 |
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| Georgiopoulos, A | 1 |
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| Grigoropoulos, P | 1 |
| Hatzopoulos, D | 1 |
| Kartalis, A | 1 |
| Lyras, A | 1 |
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| Myroforou, I | 1 |
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| Pavlidis, P | 1 |
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| Thomaidis, K | 1 |
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| Vavoulis, P | 1 |
| Vitali, MG | 1 |
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| Akbulak, RO | 1 |
| Schaeffer, B | 1 |
| Willems, S | 1 |
| Meyer, C | 1 |
| Nowak, JK | 1 |
| Szczepanik, M | 1 |
| Trypuć, M | 1 |
| Pogorzelski, A | 1 |
| Bobkowski, W | 1 |
| Grytczuk, M | 1 |
| Minarowska, A | 1 |
| Wójciak, R | 1 |
| Walkowiak, J | 1 |
| Lu, Y | 1 |
| Xi, J | 1 |
| Li, C | 1 |
| Chen, W | 2 |
| Hu, X | 1 |
| Zhang, F | 1 |
| Wei, H | 1 |
| Wang, Z | 2 |
| Gurzu, S | 1 |
| Jung, I | 1 |
| Sugimura, H | 2 |
| Stefan-van Staden, RI | 1 |
| Yamada, H | 2 |
| Natsume, H | 1 |
| Iwashita, Y | 1 |
| Szodorai, R | 1 |
| Szederjesi, J | 1 |
| Yari, D | 1 |
| Ehsanbakhsh, Z | 1 |
| Validad, MH | 1 |
| Langroudi, FH | 1 |
| Esfandiari, H | 1 |
| Prager, A | 1 |
| Hassanpour, K | 1 |
| Kurup, SP | 1 |
| Mets-Halgrimson, R | 1 |
| Yoon, H | 1 |
| Zeid, JL | 1 |
| Mets, MB | 1 |
| Rahmani, B | 1 |
| Araujo-Castillo, RV | 1 |
| Culquichicón, C | 1 |
| Solis Condor, R | 1 |
| Efendi, F | 1 |
| Sebayang, SK | 1 |
| Astutik, E | 1 |
| Hadisuyatmana, S | 1 |
| Has, EMM | 1 |
| Kuswanto, H | 1 |
| Foroutan, T | 1 |
| Ahmadi, F | 1 |
| Moayer, F | 1 |
| Khalvati, S | 1 |
| Zhang, Q | 2 |
| Lyu, Y | 1 |
| Huang, J | 1 |
| Yu, N | 1 |
| Wen, Z | 1 |
| Hou, H | 1 |
| Zhao, T | 1 |
| Gupta, A | 1 |
| Khosla, N | 1 |
| Govindasamy, V | 1 |
| Saini, A | 1 |
| Annapurna, K | 1 |
| Dhakate, SR | 1 |
| Akkaya, Ö | 1 |
| Chandgude, AL | 1 |
| Dömling, A | 1 |
| Harnett, J | 1 |
| Oakes, K | 1 |
| Carè, J | 1 |
| Leach, M | 1 |
| Brown, D | 1 |
| Cramer, H | 1 |
| Pinder, TA | 1 |
| Steel, A | 1 |
| Anheyer, D | 1 |
| Cantu, J | 1 |
| Valle, J | 1 |
| Flores, K | 1 |
| Gonzalez, D | 1 |
| Valdes, C | 1 |
| Lopez, J | 1 |
| Padilla, V | 1 |
| Alcoutlabi, M | 1 |
| Parsons, J | 1 |
| Núñez, K | 1 |
| Hamed, M | 1 |
| Fort, D | 1 |
| Bruce, D | 1 |
| Thevenot, P | 1 |
| Cohen, A | 1 |
| Weber, P | 1 |
| Menezes, AMB | 1 |
| Gonçalves, H | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase I/II Study of the Effects of Antibiotics on Sarcoidosis Pathogenesis[NCT01074554] | Phase 1/Phase 2 | 30 participants (Actual) | Interventional | 2010-02-28 | Completed | ||
| A Multicenter, Double-Blind Study to Compare the Safety and Efficacy of Levofloxacin to That of Ciprofloxacin in the Treatment of Chronic Prostatitis[NCT00236808] | Phase 3 | 383 participants (Actual) | Interventional | 2000-05-31 | Completed | ||
| A Study to Understand the Treatment Patterns in Patients With Chronic Bacterial Prostatitis (Category II), Chronic Pelvic Pain (Category IIIA, IIIB)Treataprost Added to Standard Antibiotic Treatment in Real-life Clinical Practice[NCT05306314] | 140 participants (Anticipated) | Observational | 2022-04-15 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01074554)
Timeframe: Baseline to 8 weeks
| Intervention | mm (Median) |
|---|---|
| Antibiotic Regimen | -8.4 |
| Placebo Regimen | 0.07 |
Characterization of lesion severity was conducted using Modified Sarcoidosis Activity and Severity Index (SASI), measuring erythema, induration and desquamation. The modification was that the same scale was applied to any part of the body, instead of the face alone. The scale range is 0 (no problem) to 72 (very severe). (NCT01074554)
Timeframe: Baseline to 8 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Antibiotic Regimen | -2.9 |
| Placebo Regimen | -0.6 |
Number of patients with a decrease in Granuloma Burden (only in those patients having granulomas present at baseline biopsy) (NCT01074554)
Timeframe: Baseline to 8 weeks
| Intervention | participants (Number) |
|---|---|
| Antibiotic Regimen | 7 |
| Placebo Regimen | 0 |
14 reviews available for ofloxacin and Chronic Disease
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Topical versus systemic antibiotics for chronic suppurative otitis media.
Topics: Administration, Topical; Adult; Aminoglycosides; Amoxicillin-Potassium Clavulanate Combination; Anti | 2021 |
Successful approach to treatment of Helicobacter bilis infection in X-linked agammaglobulinemia.
Topics: Adolescent; Adult; Agammaglobulinemia; Anti-Bacterial Agents; Azithromycin; beta-Lactams; Chronic Di | 2012 |
MP-376 (Aeroquin) for chronic Pseudomonas aeruginosa infections.
Topics: Administration, Inhalation; Anti-Bacterial Agents; Chronic Disease; Clinical Trials as Topic; Drug D | 2013 |
Role of levofloxacin in the treatment of lower respiratory tract infections (LRTIs).
Topics: Administration, Oral; Anti-Infective Agents; Bronchitis; Chronic Disease; Community-Acquired Infecti | 2004 |
[Treatment of chronic hepatitis C: still many problems pending].
Topics: Adrenal Cortex Hormones; Aged; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antiv | 1997 |
The use of levofloxacin in the treatment of respiratory tract infection.
Topics: Anti-Infective Agents; Bronchitis; Chronic Disease; Community-Acquired Infections; Haemophilus Infec | 2000 |
In vitro and in vivo antimicrobial activity of topical ofloxacin and other ototopical agents.
Topics: Acute Disease; Anti-Infective Agents; Anti-Infective Agents, Local; Chronic Disease; Clinical Trials | 2001 |
Efficacy of ofloxacin and other ototopical preparations for chronic suppurative otitis media in children.
Topics: Anti-Infective Agents; Anti-Infective Agents, Local; Bacteria; Child; Chronic Disease; Humans; Middl | 2001 |
The use of topical ofloxacin for otic diseases in infants and children. Summary and conclusions.
Topics: Acute Disease; Anti-Infective Agents; Anti-Infective Agents, Local; Chronic Disease; Humans; Middle | 2001 |
[The first 'respiration' fluoroquinolone--levofloxacin (Tavanic) in therapy of bacterial infections. Pharmacodynamics principles in optimization of administration regimens].
Topics: Acute Disease; Animals; Anti-Infective Agents; Bronchitis; Chronic Disease; Community-Acquired Infec | 2001 |
Use of quinolones for the treatment of acute exacerbations of chronic bronchitis.
Topics: Acute Disease; Anti-Infective Agents; Bronchitis; Chronic Disease; Ciprofloxacin; Fluoroquinolones; | 1991 |
Pharmacokinetics of fluoroquinolones in hepatic failure.
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Female; Ha | 1990 |
Toxicologic evaluation of ofloxacin.
Topics: Abnormalities, Drug-Induced; Acute Disease; Animals; Chronic Disease; Dogs; Ofloxacin; Rats | 1989 |
64 trials available for ofloxacin and Chronic Disease
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Oral antimycobacterial therapy in chronic cutaneous sarcoidosis: a randomized, single-masked, placebo-controlled study.
Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Azithromycin; CD4-Positive T-Lymphocytes; | 2013 |
Efficacy and safety of ofloxacin and its combination with dexamethasone in chronic suppurative otitis media. A randomised, double blind, parallel group, comparative study.
Topics: Adult; Anti-Bacterial Agents; Chronic Disease; Dexamethasone; Double-Blind Method; Drug Therapy, Com | 2015 |
Oral levofloxacin 500 mg once daily in the treatment of chronic bacterial prostatitis.
Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Chronic Disease; Gram-Negative Bacteria; Gram-Po | 2008 |
Nebulized bacitracin/colimycin: a treatment option in recalcitrant chronic rhinosinusitis with Staphylococcus aureus? A double-blind, randomized, placebo-controlled, cross-over pilot study.
Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacitracin; Chron | 2008 |
A prospective study determining the efficacy of topical 0.5% levofloxacin on bacterial flora of patients with chronic blepharoconjunctivitis.
Topics: Administration, Topical; Anti-Bacterial Agents; Blepharitis; Chronic Disease; Colony Count, Microbia | 2009 |
Assessing the efficacy of tragal pumping: a randomized controlled trial.
Topics: Anti-Bacterial Agents; Child; Child, Preschool; Chronic Disease; Double-Blind Method; Ear Canal; Fem | 2011 |
[Efficacy of compound Xuanju capsule in the treatment of chronic prostatitis with erectile dysfunction].
Topics: Adult; Capsules; Chronic Disease; Drugs, Chinese Herbal; Erectile Dysfunction; Humans; Levofloxacin; | 2012 |
Levofloxacin versus ciprofloxacin in the treatment of chronic bacterial prostatitis: a randomized double-blind multicenter study.
Topics: Adult; Anti-Infective Agents; Bacterial Infections; Chronic Disease; Ciprofloxacin; Double-Blind Met | 2003 |
Levofloxacin for chronic prostatitis/chronic pelvic pain syndrome in men: a randomized placebo-controlled multicenter trial.
Topics: Adult; Aged; Anti-Infective Agents; Chronic Disease; Double-Blind Method; Humans; Levofloxacin; Male | 2003 |
A randomized, double-blind study comparing 5 days oral gemifloxacin with 7 days oral levofloxacin in patients with acute exacerbation of chronic bronchitis.
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Bronchitis; Chronic Disease; Double-Blind | 2004 |
[Efficacy of levofloxacin (Tavanic) in the treatment of children with chronic pulmonary diseases].
Topics: Administration, Oral; Adolescent; Anti-Bacterial Agents; Bronchopneumonia; Child; Chronic Disease; H | 2004 |
Patient stratification in the management of acute bacterial exacerbation of chronic bronchitis: the role of levofloxacin 750 mg.
Topics: Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Amoxicillin-Potassium Clavul | 2005 |
Treatment of chronic bacterial prostatitis with levofloxacin and ciprofloxacin lowers serum prostate specific antigen.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; | 2005 |
Levofloxacin 750 mg QD for five days versus amoxicillin/clavulanate 875 mg/125 mg BID for ten days for treatment of acute bacterial exacerbation of chronic bronchitis: a post hoc analysis of data from severely ill patients.
Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacterial Infections; Br | 2006 |
[Longqingpian combined with levofloxacin highly effective for type IIIA prostatitis].
Topics: Adult; Chronic Disease; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Phytotherapy; Prostatiti | 2007 |
Prulifloxacin versus levofloxacin in the treatment of chronic bacterial prostatitis: a prospective, randomized, double-blind trial.
Topics: Adult; Anti-Bacterial Agents; Chronic Disease; Dioxolanes; Double-Blind Method; Fluoroquinolones; Hu | 2007 |
[Yiqigushen capsule combined with levofloxacin highly effective for type III A prostatitis].
Topics: Adult; Anti-Infective Agents, Urinary; Capsules; Chronic Disease; Drug Therapy, Combination; Drugs, | 2008 |
The treatment of chronic suppurative otitis media and otitis externa with 0.3 per cent ofloxacin otic solution: a clinico-microbiological study.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Chronic Disease; Hum | 1995 |
[Use of ofloxacin in the treatment of infections of the lower respiratory tract].
Topics: Adolescent; Adult; Asthma; Bronchitis; Chronic Disease; Female; Gram-Negative Bacterial Infections; | 1994 |
Antimicrobial treatment for chronic prostatitis as a means of defining the role of Ureaplasma urealyticum.
Topics: Adult; Aged; Chronic Disease; Humans; Leukocyte Count; Male; Middle Aged; Minocycline; Ofloxacin; Pr | 1993 |
[Medical management of chronic Chlamydia trachomatis salpingitis resistant to usual antibiotics. Use of ofloxacin alone or combined with other anti-chlamydia antibiotics].
Topics: Adult; Chlamydia Infections; Chlamydia trachomatis; Chronic Disease; Doxycycline; Drug Resistance, M | 1993 |
Effectiveness and safety of ofloxacin in chronic otitis media and chronic sinusitis in adult outpatients.
Topics: Administration, Oral; Adult; Ambulatory Care; Bacterial Infections; Chronic Disease; Humans; Ofloxac | 1993 |
Clinical experiences with ofloxacin sequential therapy in chronic ear infections.
Topics: Administration, Oral; Adult; Bacterial Infections; Chronic Disease; Drug Administration Schedule; Fe | 1993 |
Antibiotic treatment of sinusitis in general practice. A double-blind study comparing ofloxacin and erythromycin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chronic Disease; Double-Blind Method; Erythromycin; Fami | 1993 |
Inhibitory effect of ofloxacin on acute exacerbations of chronic respiratory tract infections in comparison with erythromycin.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Chronic Disease; Cross | 1995 |
Causative organisms in acute exacerbation of chronic airways disease and response to ofloxacin therapy.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Chronic Disease; Female; Humans; Male; Middle Aged; | 1995 |
Clinical efficacy of ofloxacin in acute exacerbations of chronic respiratory disease.
Topics: Anti-Infective Agents; Chronic Disease; Humans; Ofloxacin; Respiratory Tract Infections | 1995 |
Ofloxacin eardrop treatment for active chronic suppurative otitis media: prospective randomized study.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amoxicillin; Amoxicillin-Potassium Clavulanate Combin | 1994 |
A double-blind comparative study of ofloxacin otic drops versus neomycin-polymyxin B-hydrocortisone otic drops in the medical treatment of chronic suppurative otitis media.
Topics: Anti-Infective Agents; Chronic Disease; Double-Blind Method; Drug Combinations; Humans; Hydrocortiso | 1996 |
[Chronic osteitis--modern therapy].
Topics: Administration, Oral; Anti-Infective Agents; Chronic Disease; Drug Administration Schedule; Enteroba | 1996 |
[Stepdown ofloxacin therapy in bronchopulmonary diseases].
Topics: Administration, Oral; Anti-Infective Agents; Bronchitis; Chronic Disease; Drug Administration Schedu | 1996 |
[Comprehensive treatment with ofloxacin in pyo-inflammatory urologic diseases].
Topics: Acute Disease; Administration, Oral; Adult; Aged; Anti-Infective Agents, Urinary; Anti-Inflammatory | 1996 |
A preliminary report: clinical effects of otic solution of ofloxacin in infantile myringitis and chronic otitis media.
Topics: Anti-Infective Agents; Child; Chronic Disease; Female; Humans; Male; Ofloxacin; Otitis Media with Ef | 1998 |
Sparfloxacin vs ofloxacin in the treatment of acute bacterial exacerbations of chronic bronchitis: a multicenter, double-blind, randomized, comparative study. Sparfloxacin Multicenter ABECB Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Chlamy | 1998 |
Levofloxacin versus cefuroxime axetil in the treatment of acute exacerbation of chronic bronchitis: results of a randomized, double-blind study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Cefuroxime; Cephalosporins; Chron | 1999 |
Clinical effectiveness of levofloxacin in patients with acute purulent exacerbations of chronic bronchitis: the relationship with in-vitro activity.
Topics: Aged; Anti-Infective Agents; Bronchitis; Cefuroxime; Cephalosporins; Chronic Disease; Double-Blind M | 1999 |
[Effectiveness of maxaquin and tarivid in combined therapy of patients with chronic sinusitis].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Antitubercular Agents; Chronic Disease; Drug Therapy | 1999 |
Ciprofloxacin, lomefloxacin, or levofloxacin as treatment for chronic osteomyelitis.
Topics: Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Female; Fluoroquinolones; Follow-Up St | 2000 |
[The importance of fluoroquinolones in treating pneumonia in the elderly].
Topics: Aged; Anti-Infective Agents; Bronchitis; Chronic Disease; Dose-Response Relationship, Drug; Fluoroqu | 1999 |
Comparison of ofloxacin otic solution with oral amoxycillin plus chloramphenicol ear drop in treatment of chronic suppurative otitis media with acute exacerbation.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Amoxicillin; Anti-Infective | 2000 |
Oral ofloxacin versus parenteral imipenem-cilastatin in the treatment of osteomyelitis.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Chronic Disease; Cilast | 1999 |
Predictors of patient response to antibiotic therapy for the chronic prostatitis/chronic pelvic pain syndrome: a prospective multicenter clinical trial.
Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Antibodies, Bacterial; Bacteria; Bacterial In | 2001 |
Preoperative topical ofloxacin solution for tympanoplasty: a randomized, controlled study.
Topics: Adult; Anti-Infective Agents; Chronic Disease; Female; Humans; Male; Myringoplasty; Ofloxacin; Otiti | 2002 |
A controlled study of rifabutin and an uncontrolled study of ofloxacin in the retreatment of patients with pulmonary tuberculosis resistant to isoniazid, streptomycin and rifampicin. Hong Kong Chest Service/British Medical Research Council.
Topics: Adult; Aged; Antitubercular Agents; Chronic Disease; Dose-Response Relationship, Drug; Drug Resistan | 1992 |
[The use of ofloxacin in cystic fibrosis patients].
Topics: Adolescent; Adult; Analysis of Variance; Chronic Disease; Cystic Fibrosis; Drug Tolerance; Female; H | 1992 |
Once daily versus every two week multidose ofloxacin in patients with acute exacerbations of chronic respiratory disease.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Bacterial Infections; Bronchiectasis; Bronchitis; Chr | 1991 |
Double-blind comparative study of ofloxacin (Hoe 280) and trimethoprim-sulfamethoxazole in the treatment of patients with acute exacerbations of chronic bronchitis and chronic obstructive lung disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bronchitis; Chronic Disease; Double-Blind Method; Female | 1991 |
Topical chemotherapy in human periodontitis using a new controlled-release insert containing ofloxacin. I. Microbiological observation.
Topics: Administration, Topical; Adult; Analysis of Variance; Bacteria; Chronic Disease; Colony Count, Micro | 1991 |
[Treatment of acute exacerbations of chronic bronchitis. Multicenter, randomized comparative study of cefuroxime axetil versus ofloxacin].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Bronchitis; Cefuroxime; Chronic Di | 1991 |
Ofloxacin versus parenteral therapy for chronic osteomyelitis.
Topics: Administration, Oral; Adult; Aged; Cefazolin; Ceftazidime; Chronic Disease; Female; Gram-Negative Ba | 1991 |
Open randomized controlled parallel study of ofloxacin versus trimethoprim-sulfamethoxazole treatment of lower respiratory tract and urinary infections.
Topics: Acute Disease; Aged; Bronchitis; Bronchopneumonia; Chronic Disease; Cystitis; Escherichia coli; Fema | 1991 |
Oral ofloxacin once daily and doxycycline in the treatment of acute exacerbations of chronic bronchitis.
Topics: Administration, Oral; Bronchitis; Chronic Disease; Doxycycline; Drug Administration Schedule; Female | 1990 |
A comparative study of ofloxacin and pivmecillinam in acute exacerbations of chronic bronchitis.
Topics: Adult; Aged; Aged, 80 and over; Amdinocillin Pivoxil; Bronchitis; Chronic Disease; Double-Blind Meth | 1990 |
Overview of experience with ofloxacin in respiratory tract infection.
Topics: Bronchitis; Chronic Disease; Humans; Ofloxacin; Pneumonia; Remission Induction; Respiratory Tract In | 1990 |
[Clinical evaluation of ofloxacin in the treatment of chronic complicated urinary tract infection].
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Chronic Disease; Female; Humans; M | 1990 |
A double-blind comparison of low-dose ofloxacin and amoxycillin/clavulanic acid in acute exacerbations of chronic bronchitis.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Bronchitis; Chronic Disease; Clavulanic | 1990 |
[2 cases of drug-resistant pulmonary tuberculosis treated with ofloxacin].
Topics: Adult; Antitubercular Agents; Chronic Disease; Clinical Trials as Topic; Drug Resistance, Microbial; | 1989 |
[Topical chemotherapy of chronic periodontitis using controlled-release insert containing ofloxacin (PT-01) without root planing].
Topics: Chronic Disease; Delayed-Action Preparations; Humans; Ofloxacin; Periodontitis | 1989 |
The use of quinolones in respiratory tract infections.
Topics: Anti-Infective Agents; Bronchitis; Chronic Disease; Clinical Trials as Topic; Humans; Microbial Sens | 1987 |
Efficacy of oral fluoroquinolones versus conventional intravenous antipseudomonal chemotherapy in treatment of cystic fibrosis.
Topics: Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Clinical Trials as Topic; Cystic Fibro | 1987 |
Clinical, microbiological and pharmacokinetic studies on ofloxacin in acute purulent exacerbations of chronic respiratory disease.
Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Chronic Disease; Drug Therapy, Combination; Fe | 1986 |
An open randomised comparison of ofloxacin and doxycycline in lower respiratory tract infections.
Topics: Anti-Infective Agents; Bronchitis; Chronic Disease; Doxycycline; Humans; Microbial Sensitivity Tests | 1987 |
[Respiratory tract infections--clinical results with ofloxacin].
Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Bronchitis; Chronic Disease; Clinical Trials as | 1986 |
79 other studies available for ofloxacin and Chronic Disease
| Article | Year |
|---|---|
Novel N-linked aminopiperidine-based gyrase inhibitors with improved hERG and in vivo efficacy against Mycobacterium tuberculosis.
Topics: Acute Disease; Administration, Oral; Animals; Antitubercular Agents; Bacterial Proteins; Biological | 2014 |
Biliary antibiotics irrigation for E. coli-induced chronic proliferative cholangitis and hepatolithiasis: A pathophysiological study in rabbits.
Topics: Animals; Anti-Bacterial Agents; Bacitracin; Chlorhexidine; Cholangitis; Chronic Disease; Collagen Ty | 2020 |
Topical Therapy Failure in Chronic Suppurative Otitis Media is Due to Persister Cells in Biofilms.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Biofilms; Chronic Disease; Humans; Ofloxacin; O | 2021 |
Treatment of tularemia in patient with chronic graft-versus-host disease.
Topics: Anti-Bacterial Agents; Chronic Disease; Doxycycline; Francisella tularensis; Graft vs Host Disease; | 2013 |
Comment on: Effect of topical ofloxacin on bacterial biofilms in refractory post-sinus surgery rhino-sinusitis.
Topics: Biofilms; Chronic Disease; Humans; Nose; Ofloxacin; Paranasal Sinuses; Rhinitis; Sinusitis | 2016 |
[Chronic prostatitis and biofilm].
Topics: Adult; Biofilms; Chronic Disease; Ciprofloxacin; Contraception Behavior; Diet; Disease Susceptibilit | 2009 |
Fluoroquinolone-resistant Pseudomonas aeruginosa in chronic rhinosinusitis.
Topics: Anti-Bacterial Agents; Chronic Disease; Ciprofloxacin; Comorbidity; Drug Resistance, Bacterial; Fluo | 2009 |
In vitro pharmacodynamics of levofloxacin and other aerosolized antibiotics under multiple conditions relevant to chronic pulmonary infection in cystic fibrosis.
Topics: Aerosols; Anti-Bacterial Agents; Bacteria; Biofilms; Chronic Disease; Ciprofloxacin; Colony Count, M | 2010 |
Levofloxacin reduces inflammatory cytokine levels in human bronchial epithelia cells: implications for aerosol MP-376 (levofloxacin solution for inhalation) treatment of chronic pulmonary infections.
Topics: Administration, Inhalation; Aerosols; Anti-Inflammatory Agents; Cell Line; Chronic Disease; Epitheli | 2011 |
[Persistent pleuropneumopathy in a young woman].
Topics: Adult; Anti-Bacterial Agents; Bronchopulmonary Sequestration; Bronchoscopy; Chronic Disease; Drug Th | 2010 |
[Practice management of chronic bacterial prostatitis with levofloxacin].
Topics: Adult; Aged; Anti-Infective Agents, Urinary; Bacterial Infections; Chronic Disease; Escherichia coli | 2011 |
[Transepithelial phototherapeutic keratectomy to treat chronic laser in situ keratomileusis-flap macrostriae. A case review].
Topics: Antibiotic Prophylaxis; Astigmatism; Chronic Disease; Contact Lenses; Corneal Edema; Dexamethasone; | 2012 |
Extensive dural sinus thrombosis and bilateral lateral rectus palsy as an uncommon complication of chronic suppurative otitis media.
Topics: Abducens Nerve Diseases; Adolescent; Anti-Bacterial Agents; Ceftriaxone; Chronic Disease; Fibrinolyt | 2013 |
[Update on the use of levofloxacin in the management of acute exacerbations of chronic bronchitis with risk factors].
Topics: Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis; Chron | 2002 |
[Sensitivity to levofloxacin of Mycobacterium tuberculosis strains with various phenotype isolated from patients with newly diagnosed and chronic tuberculosis].
Topics: Anti-Infective Agents; Chronic Disease; Drug Resistance, Bacterial; Genotype; Humans; Levofloxacin; | 2002 |
[Clinical and bacteriology observation on intraoperation usage of tarivid otic solution in treatment of chronic otitis media with cholesteatoma].
Topics: Adult; Aged; Anti-Infective Agents; Cholesteatoma, Middle Ear; Chronic Disease; Combined Modality Th | 1999 |
[Epidemiological study on patients with pneumococcal respiratory tract infection in a Japanese health facility during the past year].
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactams; Ceph | 2001 |
[Detection of bacterial 16S rRAN gene in EPS of men with chronic pelvic pain syndrome and its clinical significance].
Topics: Anti-Bacterial Agents; Azithromycin; Chronic Disease; Humans; Levofloxacin; Male; Ofloxacin; Pelvic | 2003 |
Effects of androgen deprivation on chronic bacterial prostatitis in a rat model.
Topics: Androgen Antagonists; Animals; Anti-Infective Agents, Urinary; Castration; Chronic Disease; Enzyme I | 2003 |
Bacteriology of chronic suppurative otitis media in congolese children.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Chronic Disease; Citrobacter; Congo; Fem | 2003 |
[Two cases of encrusted cystitis].
Topics: Aged; Aged, 80 and over; Alkalosis; Anti-Infective Agents, Urinary; Calcium Carbonate; Carbonates; C | 2004 |
Postoperative Corynebacterium macginleyi endophthalmitis.
Topics: Aged; Aqueous Humor; Bacterial Typing Techniques; Cataract Extraction; Chronic Disease; Corynebacter | 2004 |
[A case of pulmonary multiresistant Mycobacterium bovis tuberculosis in Madagascar].
Topics: Amikacin; Antitubercular Agents; Capreomycin; Chronic Disease; Ciprofloxacin; Cough; DNA, Bacterial; | 2003 |
[Efficacy of levofloxacin in the treatment of acute exacerbation of chronic bronchitis in patients with risk factors].
Topics: Acute Disease; Anti-Bacterial Agents; Bronchitis; Chronic Disease; Clinical Trials as Topic; Humans; | 2004 |
Microbiological analysis of chronic dacryocystitis.
Topics: Adolescent; Adult; Aged; Amikacin; Anti-Bacterial Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Ch | 2005 |
Chlamydia trachomatis survival in the presence of two fluoroquinolones (lomefloxacin versus levofloxacin) in patients with chronic prostatitis syndrome.
Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Chronic Disease; Fluoroquinolones; Humans; Levofloxaci | 2005 |
The value of follow-up after acute Q fever infection.
Topics: Anti-Bacterial Agents; Antibodies, Bacterial; Chronic Disease; Complement Fixation Tests; Coxiella b | 2006 |
A review of the therapeutic uses of ofloxacin.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bronchitis; Chronic | 1989 |
Clinical efficacy and tolerability of levofloxacin in patients with liver disease: a prospective, non comparative, observational study.
Topics: Administration, Oral; Anti-Bacterial Agents; Chronic Disease; Drug Tolerance; Female; Humans; Levofl | 2006 |
Re: treatment of chronic bacterial prostatitis with levofloxacin and ciprofloxacin lowers serum prostate specific antigen.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Chronic Disease; Ciprofloxacin; | 2006 |
Penetration of levofloxacin into paranasal sinuses mucosa of patients with chronic rhinosinusitis after a single 500 mg oral dose.
Topics: Adult; Aged; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Chronic Disease; Female; H | 2007 |
[Drug-resistant bacteria isolated from pharyngeal swab cultures and urine in acutely or chronically febrile elderly nursing home inmates].
Topics: Acute Disease; Aged; Chronic Disease; Drug Resistance, Bacterial; Escherichia coli; Fever; Fluoroqui | 2007 |
Fluoroquinolone-resistant group B streptococci in acute exacerbation of chronic bronchitis.
Topics: Acute Disease; Aged, 80 and over; Anti-Bacterial Agents; Bronchitis; Chronic Disease; DNA Gyrase; Dr | 2008 |
Daily single-dose regimen and alternate-two-week triple-dose/day regimen of oral ofloxacin for the prophylaxis and control of exacerbations of chronic respiratory tract infections.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Chronic Disease; Drug Administration Schedule; | 1995 |
Failure of drug penetration and acquisition of drug resistance in chronic tuberculous empyema.
Topics: Aged; Antitubercular Agents; Chronic Disease; Empyema, Tuberculous; Ethambutol; Humans; Male; Ofloxa | 1995 |
Ofloxacin otic solution as treatment of chronic suppurative otitis media and diffuse bacterial otitis externa.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Child; Child, Preschool; Chronic Disease; Humans; In | 1995 |
Bacteriology of chronic suppurative otitis media: ofloxacin susceptibility.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Chronic Disease; Female; Human | 1995 |
Effective monitoring of concentrations of ofloxacin in saliva of patients with chronic respiratory tract infections.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Female; Humans; Kidney Diseases; Male; Middle Aged; | 1994 |
[Pancreas penetration by ofloxacin--a pilot study].
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Bile; Cholestasis, Extrahepatic; Chronic Disease; Duodenal Ne | 1993 |
In vitro susceptibility to ciprofloxacin of bacterial strains isolated from chronic otitis media and chronic sinusitis.
Topics: Adult; Anti-Infective Agents; Bacteria; Chronic Disease; Ciprofloxacin; Drug Resistance, Microbial; | 1995 |
Levofloxacin in patients with severe respiratory tract infection.
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Asthma; Bronchitis; Chronic Disease; Clarithromy | 1995 |
Quinolone resistance in Oligella urethralis-associated chronic ambulatory peritoneal dialysis peritonitis.
Topics: Adult; Aged; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Drug Resistance, Microbial; Huma | 1996 |
Effects of combination therapy with interferon and ofloxacin on chronic type C hepatitis: a pilot study.
Topics: Adult; Anti-Infective Agents; Antiviral Agents; Chronic Disease; Drug Therapy, Combination; Female; | 1996 |
Sparfloxacin and levofloxacin.
Topics: Administration, Oral; Anti-Infective Agents; Bronchitis; Chronic Disease; Clinical Trials as Topic; | 1997 |
[Treatment of lower respiratory tract infections in the elderly].
Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; A | 1997 |
[Treatment of patients for chronic pulmonary tuberculosis with expectoration--selection and tolerance to drugs].
Topics: Antitubercular Agents; Chronic Disease; Drug Therapy, Combination; Drug Tolerance; Humans; Incidence | 1997 |
Jarisch-Herxheimer reaction complicating the treatment of chronic Q fever endocarditis: elevated TNFalpha and IL-6 serum levels.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Chronic Disease; Coxiella burnetii; Doxycycline; Drug | 1998 |
Ofloxacin otic solution in patients with otitis media: an analysis of drug concentrations.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Child; Child, Preschool; Chronic | 1999 |
[Rehabilitation of patients with chronic purulent otitis media].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Chronic Disease; Humans; Ofloxacin; Otitis Media, Supp | 1999 |
Comparative in-vitro activity of levofloxacin against isolates of bacteria from adult patients with community-acquired lower respiratory tract infections.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacteria; Bronchitis; Chronic Disease; Commun | 1999 |
[Clinical success of treatment of chronic otitis media using topical and peroral administration of ofloxacin].
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Anti-Infective Agents; Chronic Dis | 1999 |
National guideline for the management of prostatitis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases).
Topics: Adrenergic alpha-Antagonists; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, U | 1999 |
[Levofloxacin concentrations in serum, sputum and lung tissue: evaluation of its efficacy according to breakpoint].
Topics: Adult; Aged; Chronic Disease; Female; Humans; Levofloxacin; Lung; Male; Middle Aged; Ofloxacin; Pneu | 1999 |
Association of chronic urinary symptoms in women and Ureaplasma urealyticum.
Topics: Adolescent; Adult; Aged; Azithromycin; Bacteriological Techniques; Bacteriuria; Chronic Disease; Cys | 2000 |
[Use of antibiotics in chronic bronchitis].
Topics: Administration, Oral; Adult; Ampicillin; Anti-Infective Agents; Bronchitis; Chronic Disease; Female; | 2000 |
Combination therapy for chronic Pseudomonas aeruginosa respiratory infection associated with biofilm formation.
Topics: Animals; Biofilms; Chronic Disease; Clarithromycin; Disease Models, Animal; Drug Therapy, Combinatio | 2000 |
Workplace costs associated with acute exacerbation of chronic bronchitis: a comparison of moxifloxacin and levofloxacin.
Topics: Absenteeism; Adolescent; Adult; Anti-Infective Agents; Bronchitis; Chronic Disease; Cost of Illness; | 2001 |
Rifampicin-ofloxacin oral regimen for the treatment of mild to moderate diabetic foot osteomyelitis.
Topics: Administration, Oral; Aged; Anti-Infective Agents; Antibiotics, Antitubercular; Bacterial Infections | 2001 |
Treatment of chronic suppurative otitis media with ofloxacin in hydroxypropyl methylcellulose ear drops: a clinical/bacteriological study in a rural area of Malawi.
Topics: Adolescent; Adult; Anti-Infective Agents; Bacteriological Techniques; Child; Child, Preschool; Chron | 2002 |
[Chronic bronchitis. What antibiotic in acute exacerbations. Good and fast effectiveness is needed].
Topics: Aged; Anti-Infective Agents; Bronchitis; Chronic Disease; Female; Humans; Male; Middle Aged; Ofloxac | 2002 |
Vinegar treatment in the management of granular myringitis.
Topics: Acetic Acid; Adolescent; Adult; Anti-Infective Agents; Chronic Disease; Female; Follow-Up Studies; G | 2002 |
[Ofloxacin in the treatment of lower respiratory tract infections in patients with chronic pulmonary diseases].
Topics: Chronic Disease; Humans; Lung Diseases; Ofloxacin; Respiratory Tract Infections | 1992 |
[Sputum penetration of levofloxacin and its clinical efficacy in patients with chronic lower respiratory tract infections].
Topics: Aged; Chronic Disease; Drug Evaluation; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; | 1992 |
Drug treatment of chronic tuberculous empyema.
Topics: Chronic Disease; Empyema, Tuberculous; Humans; Ofloxacin | 1992 |
[Clinical study of levofloxacin (DR-3355) on uro-genital infections--with special reference to usefulness for chronic prostatitis].
Topics: Adult; Aged; Chronic Disease; Drug Administration Schedule; Epididymitis; Escherichia coli; Humans; | 1992 |
[Facial paralysis in chronic nonspecific inflammation of the parotid].
Topics: Aged; Aprotinin; Chronic Disease; Diagnosis, Differential; Drug Therapy, Combination; Facial Paralys | 1990 |
Ofloxacin in lower respiratory tract infections.
Topics: Bacterial Infections; Bronchitis; Chronic Disease; Cross Infection; Drug Administration Schedule; Dr | 1991 |
[Evaluation of the effectiveness of ofloxacin in the treatment of respiratory tract].
Topics: Administration, Oral; Adult; Aged; Bronchitis; Chronic Disease; Drug Resistance, Microbial; Enteroco | 1991 |
Bronchial penetration of ofloxacin after single and multiple oral dosage.
Topics: Administration, Oral; Adult; Bronchi; Bronchitis; Chronic Disease; Drug Administration Schedule; Fem | 1991 |
Efficacy of oral administration of ofloxacin in lower respiratory tract infections in aged patients with chronic lung disease.
Topics: Administration, Oral; Aged; Aged, 80 and over; Bacterial Infections; Bronchitis; Chronic Disease; Fe | 1991 |
[Urogenital chlamydiosis].
Topics: Adult; Chlamydia Infections; Chronic Disease; Diagnosis, Differential; Female; Female Urogenital Dis | 1990 |
Successful treatment of chronic Salmonella excretor with ofloxacin.
Topics: Adult; Anti-Infective Agents; Carrier State; Chronic Disease; Humans; Male; Ofloxacin; Oxazines; Sal | 1986 |
[New oral quinolone compounds in chronic bronchitis].
Topics: Administration, Oral; Anti-Bacterial Agents; Bacterial Infections; Bronchitis; Chronic Disease; Cipr | 1986 |
[The role of ofloxacin (Tarivid) therapy in respiratory and urinary tract infections].
Topics: Acute Disease; Chronic Disease; Escherichia coli; Humans; Klebsiella; Ofloxacin; Proteus; Pseudomona | 1987 |
[Ofloxacin in the conservative therapy of acute and chronic otitis media--a preliminary clinical report of experiences].
Topics: Acute Disease; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Chronic Disease; Humans; Oflox | 1986 |
Clinical evaluation of ofloxacin in lower respiratory tract infections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Chronic Disease; Female; Humans; | 1986 |
Ofloxacin in oral chemotherapy of acute and chronic otitis media.
Topics: Acute Disease; Anti-Bacterial Agents; Chronic Disease; Ear, Middle; Humans; Ofloxacin; Otitis Media; | 1986 |
[In vitro antibacterial activity and pharmacokinetics of ofloxacin in chronic respiratory tract infections].
Topics: Anti-Bacterial Agents; Bacteria; Bronchitis; Chronic Disease; Drug Resistance, Microbial; Humans; Of | 1987 |
Ofloxacin treatment in the management of chronic osteitis.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteria; Chronic Disease; Female; Humans; Male; Microbial Sensi | 1987 |