Page last updated: 2024-11-01

ofloxacin and Cholangitis

ofloxacin has been researched along with Cholangitis in 7 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Cholangitis: Inflammation of the biliary ductal system (BILE DUCTS); intrahepatic, extrahepatic, or both.

Research Excerpts

ExcerptRelevanceReference
"The clinical effect of Levofloxacin and Ceftriaxone in patients with acute cholangitis showed no significant differences."9.10[Ceftriaxone versus Levofloxacin for antibiotic therapy in patients with acute cholangitis]. ( Genitsariotis, R; Hahn, M; Jung, M; Kiesslich, R; Mäurer, M; Nafe, B; Will, D, 2003)
"The clinical effect of Levofloxacin and Ceftriaxone in patients with acute cholangitis showed no significant differences."5.10[Ceftriaxone versus Levofloxacin for antibiotic therapy in patients with acute cholangitis]. ( Genitsariotis, R; Hahn, M; Jung, M; Kiesslich, R; Mäurer, M; Nafe, B; Will, D, 2003)
"Thirteen hospitalized patients with various infections, five with typhoid fever, two with gastroenteritis, four with respiratory tract infection and two with biliary tract infection, were treated with ofloxacin at a daily dosage ranging between 600 and 900 mg orally."5.06Clinical experience with ofloxacin (DL 8280) in the therapy of various infections: preliminary report. ( Altucci, P; Briante, V; Cristiano, P; Leonessa, V; Morelli, G; Paradisi, F, 1986)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's4 (57.14)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Ma, WJ1
Wu, ZR1
Yang, Q1
Hu, HJ1
Wang, JK1
Shi, YJ1
Li, FY1
Cheng, NS1
Kiesslich, R1
Will, D1
Hahn, M1
Nafe, B1
Genitsariotis, R1
Mäurer, M1
Jung, M1
Saenko, VF1
Viktorov, AP1
Golopykho, LI1
Nichitaĭlo, ME1
Gorshevikova, EV1
Karachalios, GN1
Nasiopoulou, DD1
Bourlinou, PK1
Reppa, A1
Tanimura, H1
Ohnishi, H1
Okamura, T1
Uenishi, M1
Ichimiya, G1
Kobayashi, Y1
Aoki, Y1
Oka, S1
Yamamoto, S1
Shimada, K1
Mizuno, A1
Suzuki, T1
Taniguchi, M1
Yura, J1
Shinagawa, N1
Ishikawa, S1
Mashita, K1
Suzui, K1
Ishikawa, M1
Ishihara, H1
Cristiano, P1
Leonessa, V1
Morelli, G1
Briante, V1
Paradisi, F1
Altucci, P1

Trials

3 trials available for ofloxacin and Cholangitis

ArticleYear
[Ceftriaxone versus Levofloxacin for antibiotic therapy in patients with acute cholangitis].
    Zeitschrift fur Gastroenterologie, 2003, Volume: 41, Issue:1

    Topics: Acute Disease; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Bact

2003
Treatment of acute biliary tract infections with ofloxacin: a randomized, controlled clinical trial.
    International journal of clinical pharmacology and therapeutics, 1996, Volume: 34, Issue:12

    Topics: Anti-Infective Agents; Bacteremia; Ceftriaxone; Cephalosporins; Cholangitis; Cholecystitis; Escheric

1996
Clinical experience with ofloxacin (DL 8280) in the therapy of various infections: preliminary report.
    Infection, 1986, Volume: 14 Suppl 4

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Cholangitis; Clinical Trials a

1986

Other Studies

4 other studies available for ofloxacin and Cholangitis

ArticleYear
Biliary antibiotics irrigation for E. coli-induced chronic proliferative cholangitis and hepatolithiasis: A pathophysiological study in rabbits.
    Clinics and research in hepatology and gastroenterology, 2020, Volume: 44, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Bacitracin; Chlorhexidine; Cholangitis; Chronic Disease; Collagen Ty

2020
[A clinical evaluation of the efficacy of using Zanocin (ofloxacin) in surgery].
    Klinichna khirurhiia, 1995, Issue:9-10

    Topics: Adult; Anti-Infective Agents; Biliary Fistula; Cefazolin; Cephalosporins; Cholangitis; Drug Evaluati

1995
[Chemotherapy of biliary tract infections (XXXVII). Excretion into bile and gallbladder tissue levels of levofloxacin and its clinical effect in biliary tract infections].
    The Japanese journal of antibiotics, 1992, Volume: 45, Issue:5

    Topics: Adult; Aged; Bile; Cholangitis; Cholecystitis; Drug Evaluation; Female; Gallbladder; Humans; Levoflo

1992
[Penetration of levofloxacin in bile].
    The Japanese journal of antibiotics, 1992, Volume: 45, Issue:5

    Topics: Aged; Bile; Cholangitis; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin

1992