ofloxacin has been researched along with Cerebrospinal Fluid Otorrhea in 3 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Cerebrospinal Fluid Otorrhea: Discharge of cerebrospinal fluid through the external auditory meatus or through the eustachian tube into the nasopharynx. This is usually associated with CRANIOCEREBRAL TRAUMA (e.g., SKULL FRACTURE involving the TEMPORAL BONE;), NEUROSURGICAL PROCEDURES; or other conditions, but may rarely occur spontaneously. (From Am J Otol 1995 Nov;16(6):765-71)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roland, PS | 1 |
| Dohar, JE | 1 |
| Lanier, BJ | 1 |
| Hekkenburg, R | 1 |
| Lane, EM | 1 |
| Conroy, PJ | 1 |
| Wall, GM | 1 |
| Dupre, SJ | 1 |
| Potts, SL | 1 |
| Poetker, DM | 1 |
| Lindstrom, DR | 1 |
| Patel, NJ | 1 |
| Conley, SF | 1 |
| Flanary, VA | 1 |
| Link, TR | 1 |
| Kerschner, JE | 1 |
| Barlow, DW | 1 |
| Duckert, LG | 1 |
| Kreig, CS | 1 |
| Gates, GA | 1 |
2 trials available for ofloxacin and Cerebrospinal Fluid Otorrhea
| Article | Year |
|---|---|
Topical ciprofloxacin/dexamethasone otic suspension is superior to ofloxacin otic solution in the treatment of granulation tissue in children with acute otitis media with otorrhea through tympanostomy tubes.
Topics: Administration, Topical; Adolescent; Anti-Infective Agents; Anti-Inflammatory Agents; Cerebrospinal | 2004 |
Ofloxacin otic drops vs neomycin-polymyxin B otic drops as prophylaxis against early postoperative tympanostomy tube otorrhea.
Topics: Administration, Topical; Anti-Bacterial Agents; Cerebrospinal Fluid Otorrhea; Child, Preschool; Fema | 2006 |
1 other study available for ofloxacin and Cerebrospinal Fluid Otorrhea
| Article | Year |
|---|---|
Ototoxicity of topical otomicrobial agents.
Topics: Animals; Benzalkonium Compounds; Cerebrospinal Fluid Otorrhea; Cochlea; Drug Combinations; Ear, Midd | 1995 |