ofloxacin has been researched along with Cataract in 6 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ofloxacin, a new antibiotic of the group of quinolones, was tested for its possible cocataractogenic potential." | 7.68 | Evaluation of a possible cocataractogenic potential of Ofloxacin. ( Hockwin, O; Kuhn, UD; Lorenz, M; Wegener, A, 1990) |
| "The aim of the study was to estimate changes in bacterial flora of conjunctival sac changes in patients prophylacticaly treated with different antibiotics (chloramphenicol, gentamycin, ofloxacin, norfloxacin) before cataract operation." | 5.11 | [Changes in bacterial flora of conjunctival sac in patients prophylacticaly treated with antibiotic before cataract operation]. ( Gerkowicz, M; Gruszecka-Gerkowicz, R; Kosior-Jarecka, E; Pietraś-Trzpiel, M, 2005) |
| "We report the antiinflammatory effect and efficacy of preoperative treatment with ketorolac in a patient with rheumatoid arthritis having phacoemulsification." | 3.71 | Antiinflammatory effect of preoperative ketorolac in phacoemulsification. ( Caronia, RM; Donnenfeld, ED; Perry, HD, 2002) |
| "Ofloxacin, a new antibiotic of the group of quinolones, was tested for its possible cocataractogenic potential." | 3.68 | Evaluation of a possible cocataractogenic potential of Ofloxacin. ( Hockwin, O; Kuhn, UD; Lorenz, M; Wegener, A, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ranjan, A | 1 |
| Murthy, SI | 1 |
| Rathi, VM | 1 |
| Sangwan, VS | 1 |
| Sandmeyer, LS | 1 |
| Bauer, BS | 1 |
| Mohaghegh Poor, SM | 1 |
| Feng, CX | 1 |
| Chirino-Trejo, M | 1 |
| Huang, YS | 1 |
| Dai, YH | 1 |
| Sun, SY | 1 |
| Lan, J | 1 |
| Xie, LX | 1 |
| Caronia, RM | 1 |
| Perry, HD | 1 |
| Donnenfeld, ED | 1 |
| Gerkowicz, M | 1 |
| Gruszecka-Gerkowicz, R | 1 |
| Kosior-Jarecka, E | 1 |
| Pietraś-Trzpiel, M | 1 |
| Wegener, A | 1 |
| Kuhn, UD | 1 |
| Lorenz, M | 1 |
| Hockwin, O | 1 |
2 trials available for ofloxacin and Cataract
| Article | Year |
|---|---|
[Study of different methods in reducing conjunctival bacteria before cataract surgery].
Topics: Aged; Antibiotic Prophylaxis; Cataract; Cataract Extraction; Conjunctiva; Humans; Levofloxacin; Midd | 2009 |
[Changes in bacterial flora of conjunctival sac in patients prophylacticaly treated with antibiotic before cataract operation].
Topics: Antibiotic Prophylaxis; Cataract; Cataract Extraction; Chloramphenicol; Conjunctiva; Conjunctivitis, | 2005 |
4 other studies available for ofloxacin and Cataract
| Article | Year |
|---|---|
Acute Bilateral Toxic Endotheliitis Following Alcohol Consumption.
Topics: Acute Disease; Adult; Alcohol Drinking; Anti-Bacterial Agents; Cataract; Cataract Extraction; Cornea | 2018 |
Alterations in conjunctival bacteria and antimicrobial susceptibility during topical administration of ofloxacin after cataract surgery in dogs.
Topics: Animals; Anti-Infective Agents; Cataract; Cataract Extraction; Conjunctiva; Dog Diseases; Dogs; Drug | 2017 |
Antiinflammatory effect of preoperative ketorolac in phacoemulsification.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cataract; Drug Therapy, Combin | 2002 |
Evaluation of a possible cocataractogenic potential of Ofloxacin.
Topics: Animals; Cataract; Diabetes Mellitus, Experimental; Disease Models, Animal; Evaluation Studies as To | 1990 |