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ofloxacin and Campylobacter Infection

ofloxacin has been researched along with Campylobacter Infection in 16 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"The recommended treatment for traveler's diarrhea is the combination of an appropriate antibiotic (usually a fluoroquinolone) and loperamide."9.12Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey. ( Frenck, RW; Johnston, JR; Monteville, MR; Putnam, SD; Riddle, MS; Rockabrand, DM; Sanders, JW; Tribble, DR; Ulukan, S, 2007)
"The clinical efficacy, safety and usefulness of Rokitamycin (RKM), a new macrolide antibiotic, were compared with those of Ofloxacin (OFLX) for the treatment of Campylobacter enteritis by a double blind method."9.07[Comparison of clinical efficacy of rokitamycin (RKM) and ofloxacin (OFLX) for the treatment of Campylobacter enteritis by a double-blind method. The Research Committee for the Effect of Rokitamycin, Research Group for Infectious Enteritis]. ( Machii, A; Nitta, Y; Obana, M; Ota, S; Sagara, H; Sato, J; Seo, T; Takizawa, Y; Tomizawa, I; Tsunoda, T, 1991)
" The therapeutic combination of H2-receptor-antagonists (= H2-RA) and ofloxacin (Tarivid) has shown to heal resistant duodenal ulcers in some preliminary cases, which did not respond to a three month standard dosage treatment with H2-RA."5.27[Ofloxacin in therapy of "resistant" duodenal ulcer. A pilot study]. ( Bayerdörffer, E; Kasper, G; Ottenjann, R; Pirlet, T; Sommer, A, 1988)
"The recommended treatment for traveler's diarrhea is the combination of an appropriate antibiotic (usually a fluoroquinolone) and loperamide."5.12Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey. ( Frenck, RW; Johnston, JR; Monteville, MR; Putnam, SD; Riddle, MS; Rockabrand, DM; Sanders, JW; Tribble, DR; Ulukan, S, 2007)
"The clinical efficacy, safety and usefulness of Rokitamycin (RKM), a new macrolide antibiotic, were compared with those of Ofloxacin (OFLX) for the treatment of Campylobacter enteritis by a double blind method."5.07[Comparison of clinical efficacy of rokitamycin (RKM) and ofloxacin (OFLX) for the treatment of Campylobacter enteritis by a double-blind method. The Research Committee for the Effect of Rokitamycin, Research Group for Infectious Enteritis]. ( Machii, A; Nitta, Y; Obana, M; Ota, S; Sagara, H; Sato, J; Seo, T; Takizawa, Y; Tomizawa, I; Tsunoda, T, 1991)
"Levofloxacin's efficacy was inferior to azithromycin's efficacy, except in patients with no pathogen identified during the first 24 h of treatment or in patients with levofloxacin-susceptible Campylobacter isolates, in whom it appeared to be equal to azithromycin."2.73Traveler's diarrhea in Thailand: randomized, double-blind trial comparing single-dose and 3-day azithromycin-based regimens with a 3-day levofloxacin regimen. ( Armstrong, A; Baqar, S; Bodhidatta, L; Faix, DJ; Fox, A; Hshieh, P; Lawler, JV; Lebron, C; Lewis, M; Maley, EA; Mason, C; Nayak, G; Pang, LW; Pitarangsi, C; Sanders, JW; Scott, DA; Tribble, DR, 2007)
"Its efficacy for the treatment of human campylobacteriosis should be evaluated in clinical trials."1.36Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. ( Hakanen, AJ; Huovinen, P; Kotilainen, P; Lehtopolku, M; Nakari, UM; Siitonen, A, 2010)
" The therapeutic combination of H2-receptor-antagonists (= H2-RA) and ofloxacin (Tarivid) has shown to heal resistant duodenal ulcers in some preliminary cases, which did not respond to a three month standard dosage treatment with H2-RA."1.27[Ofloxacin in therapy of "resistant" duodenal ulcer. A pilot study]. ( Bayerdörffer, E; Kasper, G; Ottenjann, R; Pirlet, T; Sommer, A, 1988)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19905 (31.25)18.7374
1990's4 (25.00)18.2507
2000's4 (25.00)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lehtopolku, M1
Nakari, UM1
Kotilainen, P1
Huovinen, P1
Siitonen, A1
Hakanen, AJ1
Kuuliala, A1
Julkunen, H1
Paimela, L1
Peltomaa, R1
Kautiainen, H1
Repo, H1
Leirisalo-Repo, M1
Sanders, JW2
Frenck, RW1
Putnam, SD1
Riddle, MS1
Johnston, JR1
Ulukan, S1
Rockabrand, DM1
Monteville, MR1
Tribble, DR2
Aggarwal, H1
Kushnir, L1
Conti, D1
Gallichio, M1
Tobin, E1
Pang, LW1
Mason, C1
Pitarangsi, C1
Baqar, S1
Armstrong, A1
Hshieh, P1
Fox, A1
Maley, EA1
Lebron, C1
Faix, DJ1
Lawler, JV1
Nayak, G1
Lewis, M1
Bodhidatta, L1
Scott, DA1
DuPont, HL1
Saito, M1
Seo, T2
Matsubara, Y1
Tomizawa, I2
Takizawa, Y2
Ito, K1
Konishi, K1
Matsunaga, M1
Yanagishita, T1
Kosugi, M1
Landau, Z1
Agmon, NL1
Argas, D1
Arcavi, L1
Simon, D1
Miskin, A1
Schwartz, D1
Goossens, H1
Levy, J1
Butzler, JP1
Goldhar, J1
Chuma, T1
Ikeda, T1
Maeda, T1
Niwa, H1
Okamoto, K1
Obana, M1
Nitta, Y1
Sagara, H1
Sato, J1
Tsunoda, T1
Ota, S1
Machii, A1
Zelenková, J1
Toman, R1
Bielaszewská, M1
Hanika, J1
Zeman, V1
Glupczynski, Y1
Labbe, M1
Burette, A1
Delmee, M1
Avesani, V1
Bruck, C1
Bayerdörffer, E3
Simon, T1
Bästlein, C1
Ottenjann, R3
Kasper, G3
Pirlet, T2
Sommer, A2

Reviews

1 review available for ofloxacin and Campylobacter Infection

ArticleYear
Acute cholecystitis caused by Campylobacter jejuni.
    Israel journal of medical sciences, 1995, Volume: 31, Issue:11

    Topics: Acute Disease; Aged; Aged, 80 and over; Anti-Infective Agents; Campylobacter Infections; Campylobact

1995

Trials

8 trials available for ofloxacin and Campylobacter Infection

ArticleYear
Double-blind, randomized, placebo-controlled study of three-month treatment with the combination of ofloxacin and roxithromycin in recent-onset reactive arthritis.
    Rheumatology international, 2013, Volume: 33, Issue:11

    Topics: Adult; Anti-Bacterial Agents; Arthritis, Reactive; Campylobacter Infections; Chlamydia Infections; D

2013
Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Volume: 45, Issue:3

    Topics: Adult; Azithromycin; Campylobacter Infections; Diarrhea; Double-Blind Method; Drug Therapy, Combinat

2007
Traveler's diarrhea in Thailand: randomized, double-blind trial comparing single-dose and 3-day azithromycin-based regimens with a 3-day levofloxacin regimen.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Feb-01, Volume: 44, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Azithromycin; Campylobacter Infections; Campylobacter jejuni; Communit

2007
[Comparison of clinical efficacy of ofloxacin COFLX: DL-8280) and pipemidic acid (PPA) in acute infectious diarrhea by a double-blind method. The Japan Research Committee of Ofloxacin, Research Group for Acute Infectious Diarrhea].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1984, Volume: 58, Issue:10

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Campylobacter I

1984
[Comparison of clinical efficacy of rokitamycin (RKM) and ofloxacin (OFLX) for the treatment of Campylobacter enteritis by a double-blind method. The Research Committee for the Effect of Rokitamycin, Research Group for Infectious Enteritis].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1991, Volume: 65, Issue:9

    Topics: Adolescent; Adult; Aged; Campylobacter coli; Campylobacter Infections; Campylobacter jejuni; Double-

1991
Treatment failure of ofloxacin in Campylobacter pylori infection.
    Lancet (London, England), 1987, May-09, Volume: 1, Issue:8541

    Topics: Anti-Bacterial Agents; Campylobacter; Campylobacter Infections; Clinical Trials as Topic; Double-Bli

1987
Bismuth/ofloxacin combination for duodenal ulcer.
    Lancet (London, England), 1987, Dec-19, Volume: 2, Issue:8573

    Topics: Anti-Infective Agents; Bismuth; Campylobacter Infections; Clinical Trials as Topic; Drug Therapy, Co

1987
[Ofloxacin in the therapy of Campylobacter pylori-positive duodenal ulcer. A prospective controlled randomized study].
    Deutsche medizinische Wochenschrift (1946), 1987, Sep-11, Volume: 112, Issue:37

    Topics: Adult; Aged; Aged, 80 and over; Campylobacter Infections; Clinical Trials as Topic; Drug Therapy, Co

1987

Other Studies

7 other studies available for ofloxacin and Campylobacter Infection

ArticleYear
Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3

    Topics: Anti-Bacterial Agents; Campylobacter coli; Campylobacter Infections; Campylobacter jejuni; Carbapene

2010
A case of Campylobacter jejuni bacteremia in a renal transplant patient.
    Transplant infectious disease : an official journal of the Transplantation Society, 2010, Volume: 12, Issue:6

    Topics: Anti-Bacterial Agents; Bacteremia; Campylobacter Infections; Campylobacter jejuni; Diarrhea; Female;

2010
Azithromycin for the self-treatment of traveler's diarrhea.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Feb-01, Volume: 44, Issue:3

    Topics: Anti-Bacterial Agents; Azithromycin; Campylobacter Infections; Campylobacter jejuni; Community-Acqui

2007
Plasmid profiles and antimicrobial susceptibility of Campylobacter jejuni isolated from Israeli children with diarrhea.
    Zentralblatt fur Bakteriologie : international journal of medical microbiology, 1993, Volume: 279, Issue:3

    Topics: Amoxicillin; Anti-Bacterial Agents; Campylobacter Infections; Campylobacter jejuni; Child; Ciproflox

1993
Antimicrobial susceptibilities of Campylobacter strains isolated from broilers in the southern part of Japan from 1995 to 1999.
    The Journal of veterinary medical science, 2001, Volume: 63, Issue:9

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Campylobacter coli; Campylobacter

2001
[Campylobacter pylori and treatment of duodenal ulcer].
    Vnitrni lekarstvi, 1990, Volume: 36, Issue:6

    Topics: Adult; Campylobacter; Campylobacter Infections; Duodenal Ulcer; Female; Gastritis; Humans; Male; Mid

1990
[Ofloxacin in therapy of "resistant" duodenal ulcer. A pilot study].
    Zeitschrift fur Gastroenterologie, 1988, Volume: 26, Issue:3

    Topics: Adult; Aged; Anti-Bacterial Agents; Campylobacter; Campylobacter Infections; Duodenal Ulcer; Duodeno

1988