ofloxacin has been researched along with Burns in 8 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The experience with lomefloxacin and ofloxacin respectively in the complex therapy of 26 and 40 patients with burns is described." | 9.08 | [Efficacy of lomefloxacin and ofloxacin in complex therapy of infections in patients with burns]. ( Alekseev, AA; Bobrovnikov, AE; Elagina, LV; Grishina, IA; Iakovlev, VP; Izotova, GN; Krutikov, MG, 1998) |
| "Ofloxacin has been used for prevention and treatment of burn infection in 40 burnt subjects." | 5.29 | [Experience in the use of ofloxacin in the prevention and treatment of wound infection in burns]. ( Alekseev, AA; Dutikov, VN; Elagina, LV; Iakovlev, VP; Izotova, GN; Kashin, ID; Krutikov, MG, 1995) |
| "The experience with lomefloxacin and ofloxacin respectively in the complex therapy of 26 and 40 patients with burns is described." | 5.08 | [Efficacy of lomefloxacin and ofloxacin in complex therapy of infections in patients with burns]. ( Alekseev, AA; Bobrovnikov, AE; Elagina, LV; Grishina, IA; Iakovlev, VP; Izotova, GN; Krutikov, MG, 1998) |
| " The pharmacodynamic probability of target attainment (PTA) was evaluated by Monte Carlo simulation." | 1.33 | Levofloxacin pharmacokinetics and pharmacodynamics in patients with severe burn injury. ( Bauling, PC; Fish, DN; Hoody, DW; Kiser, TH; Obritsch, MD; Wegzyn, CO, 2006) |
| "The ofloxacin values were 1798." | 1.29 | Concentration of orally administered antimicrobial agent in burn scar tissue, granulation tissue, normal skin and serum. ( Kudo, M; Ohkubo, T; Sawada, Y; Sugawara, K, 1993) |
| "Ofloxacin has been used for prevention and treatment of burn infection in 40 burnt subjects." | 1.29 | [Experience in the use of ofloxacin in the prevention and treatment of wound infection in burns]. ( Alekseev, AA; Dutikov, VN; Elagina, LV; Iakovlev, VP; Izotova, GN; Kashin, ID; Krutikov, MG, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (75.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jena, J | 1 |
| Debata, NK | 1 |
| Sahoo, RK | 1 |
| Subudhi, E | 1 |
| Kiser, TH | 1 |
| Hoody, DW | 1 |
| Obritsch, MD | 1 |
| Wegzyn, CO | 1 |
| Bauling, PC | 1 |
| Fish, DN | 1 |
| Sawada, Y | 3 |
| Ohkubo, T | 1 |
| Kudo, M | 1 |
| Sugawara, K | 1 |
| Alekseev, AA | 3 |
| Iakovlev, VP | 3 |
| Krutikov, MG | 3 |
| Kashin, ID | 1 |
| Dutikov, VN | 1 |
| Elagina, LV | 3 |
| Izotova, GN | 3 |
| Bobrovnikov, AE | 1 |
| Grishina, IA | 1 |
| Ara, M | 2 |
| Yotsuyanagi, T | 2 |
| Sone, K | 2 |
2 trials available for ofloxacin and Burns
| Article | Year |
|---|---|
[Ofloxacin in comprehensive treatment of infections in burn patients].
Topics: Adult; Aged; Anti-Infective Agents; Burns; Female; Humans; Male; Microbial Sensitivity Tests; Middle | 1996 |
[Efficacy of lomefloxacin and ofloxacin in complex therapy of infections in patients with burns].
Topics: Adolescent; Adult; Anti-Infective Agents; Burns; Drug Resistance, Microbial; Drug Resistance, Multip | 1998 |
6 other studies available for ofloxacin and Burns
| Article | Year |
|---|---|
Phylogenetic study of metallo-β-lactamase producing multidrug resistant Pseudomonas aeruginosa isolates from burn patients.
Topics: Amikacin; Anti-Bacterial Agents; beta-Lactamases; Burns; Ceftazidime; Ceftriaxone; Cilastatin; Clavu | 2015 |
Levofloxacin pharmacokinetics and pharmacodynamics in patients with severe burn injury.
Topics: Adult; Anti-Bacterial Agents; Area Under Curve; Burns; Computer Simulation; Female; Half-Life; Human | 2006 |
Concentration of orally administered antimicrobial agent in burn scar tissue, granulation tissue, normal skin and serum.
Topics: Administration, Oral; Adolescent; Adult; Aged; Burns; Chromatography, High Pressure Liquid; Cicatrix | 1993 |
[Experience in the use of ofloxacin in the prevention and treatment of wound infection in burns].
Topics: Adult; Aged; Anti-Infective Agents; Bacteria; Bacteriological Techniques; Burns; Female; Humans; Mal | 1995 |
Treatment of dermal depth burn wounds with an antimicrobial agent-releasing silicone gel sheet.
Topics: Adolescent; Adult; Aged; Burns; Child; Child, Preschool; Delayed-Action Preparations; Female; Gels; | 1990 |
Experiences using silicone gel tie-over dressings following skin grafting.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Burns; Child; Child, Preschool; Female; Gels; Hematoma; | 1990 |