ofloxacin has been researched along with Bronchiectasis in 8 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Bronchiectasis: Persistent abnormal dilatation of the bronchi.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A prospective randomized study was performed in order to compare the efficacy of oral levofloxacin, a new S- isomer of ofloxacin, with intravenous ceftazidime in the empirical treatment of acute exacerbations of bronchiectasis." | 9.09 | A comparative study on the efficacy of levofloxacin and ceftazidime in acute exacerbation of bronchiectasis. ( Chan, K; Chan, WM; Ho, PL; Ip, MS; Lam, WK; Tsang, KW, 1999) |
| "Forty-one hospitalized adult patients of bronchiectasis (non-cystic fibrotic) with infective exacerbations were entered into a randomized, double-blind, placebo-controlled study comparing ofloxacin (200 mg tid) and amoxycillin (1 g tid) both orally for ten days." | 9.06 | Ofloxacin compared with amoxycillin in treating infective exacerbations in bronchiectasis. ( Chan, JC; Chau, PY; Ip, M; Lam, WK; Leung, YK; Sham, MK; So, SY, 1989) |
| "32 hospitalized adult patients with infective episodes of bronchiectasis were enrolled in an ongoing double-blind, placebo-controlled study comparing ofloxacin with amoxicillin." | 9.06 | A double-blind randomized study comparing ofloxacin and amoxicillin in treating infective episodes in bronchiectasis. ( Chan, JC; Chau, PY; Lam, WK; Leung, YK; Sham, MK; So, SY, 1986) |
| "A prospective randomized study was performed in order to compare the efficacy of oral levofloxacin, a new S- isomer of ofloxacin, with intravenous ceftazidime in the empirical treatment of acute exacerbations of bronchiectasis." | 5.09 | A comparative study on the efficacy of levofloxacin and ceftazidime in acute exacerbation of bronchiectasis. ( Chan, K; Chan, WM; Ho, PL; Ip, MS; Lam, WK; Tsang, KW, 1999) |
| "Two different oral ofloxacin regimens, daily single-dose treatment with 200 mg (Regimen I) and every two week multidose treatment with 3 x 200 mg/day (Regimen II), were compared to evaluate the efficacy of quinolone regimens in controlling acute exacerbations of chronic respiratory tract infections." | 5.07 | Once daily versus every two week multidose ofloxacin in patients with acute exacerbations of chronic respiratory disease. ( Watanabe, A, 1991) |
| "Forty-one hospitalized adult patients of bronchiectasis (non-cystic fibrotic) with infective exacerbations were entered into a randomized, double-blind, placebo-controlled study comparing ofloxacin (200 mg tid) and amoxycillin (1 g tid) both orally for ten days." | 5.06 | Ofloxacin compared with amoxycillin in treating infective exacerbations in bronchiectasis. ( Chan, JC; Chau, PY; Ip, M; Lam, WK; Leung, YK; Sham, MK; So, SY, 1989) |
| "32 hospitalized adult patients with infective episodes of bronchiectasis were enrolled in an ongoing double-blind, placebo-controlled study comparing ofloxacin with amoxicillin." | 5.06 | A double-blind randomized study comparing ofloxacin and amoxicillin in treating infective episodes in bronchiectasis. ( Chan, JC; Chau, PY; Lam, WK; Leung, YK; Sham, MK; So, SY, 1986) |
| "To explore the effects of Zhikuofang, a TCM prescription, and Ofloxacin on the inflammation and cytostatics of the airway model of bronchiectasis." | 3.71 | [Effects of the zhikuofang on the inflammation and cytostatics of the airway model of bronchiectasis]. ( Bi, JJ; Cao, SH; Wan, YG; Zhou, M; Zhou, Y; Zhu, YH, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pubill-Fondevila, N | 1 |
| Bielsa, S | 1 |
| Porcel, JM | 1 |
| Wan, YG | 1 |
| Cao, SH | 1 |
| Bi, JJ | 1 |
| Zhu, YH | 1 |
| Zhou, Y | 1 |
| Zhou, M | 1 |
| Kobayashi, H | 1 |
| Takamura, K | 1 |
| Kono, K | 1 |
| Onodera, S | 1 |
| Sasaki, N | 1 |
| Nagahama, F | 1 |
| Kawakami, Y | 1 |
| Honma, Y | 1 |
| Matsuzaki, M | 1 |
| Tanimura, K | 1 |
| Tsang, KW | 1 |
| Chan, WM | 1 |
| Ho, PL | 1 |
| Chan, K | 1 |
| Lam, WK | 3 |
| Ip, MS | 1 |
| Habib, MP | 1 |
| Watanabe, A | 1 |
| Chau, PY | 2 |
| So, SY | 2 |
| Leung, YK | 2 |
| Chan, JC | 2 |
| Ip, M | 1 |
| Sham, MK | 2 |
1 review available for ofloxacin and Bronchiectasis
| Article | Year |
|---|---|
Management of clinical failures in non-ICU patients with chronic obstructive pulmonary disease exacerbations.
Topics: Adrenal Cortex Hormones; Anti-Infective Agents; Bronchiectasis; Humans; Male; Ofloxacin; Pulmonary D | 2001 |
5 trials available for ofloxacin and Bronchiectasis
| Article | Year |
|---|---|
[Comparison of DL-8280 and amoxicillin in the treatment of respiratory tract infections].
Topics: Adult; Aged; Amoxicillin; Anti-Infective Agents; Bronchiectasis; Bronchitis; Clinical Trials as Topi | 1984 |
A comparative study on the efficacy of levofloxacin and ceftazidime in acute exacerbation of bronchiectasis.
Topics: Acute Disease; Administration, Oral; Anti-Infective Agents; Bronchiectasis; Ceftazidime; Cephalospor | 1999 |
Once daily versus every two week multidose ofloxacin in patients with acute exacerbations of chronic respiratory disease.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Bacterial Infections; Bronchiectasis; Bronchitis; Chr | 1991 |
Ofloxacin compared with amoxycillin in treating infective exacerbations in bronchiectasis.
Topics: Adult; Amoxicillin; Bacteria; Bacterial Infections; Bronchiectasis; Double-Blind Method; Female; Hum | 1989 |
A double-blind randomized study comparing ofloxacin and amoxicillin in treating infective episodes in bronchiectasis.
Topics: Adult; Aged; Amoxicillin; Anti-Infective Agents; Bronchiectasis; Clinical Trials as Topic; Double-Bl | 1986 |
2 other studies available for ofloxacin and Bronchiectasis
| Article | Year |
|---|---|
[Levofloxacin hepatotoxicity].
Topics: Adult; Alanine Transaminase; Anti-Bacterial Agents; Aspartate Aminotransferases; Bronchiectasis; Bro | 2013 |
[Effects of the zhikuofang on the inflammation and cytostatics of the airway model of bronchiectasis].
Topics: Animals; Anti-Infective Agents; Bronchiectasis; Bronchitis; Drug Combinations; Drugs, Chinese Herbal | 2002 |