Page last updated: 2024-11-01

ofloxacin and Brain Inflammation

ofloxacin has been researched along with Brain Inflammation in 2 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"The penetration of ofloxacin was studied in 22 patients with purulent meningitis or ventriculitis treated with conventional antibiotics."7.67Diffusion of ofloxacin into cerebrospinal fluid of patients with purulent meningitis or ventriculitis. ( Clair, B; Laisne, MJ; Pioget, JC; Regnier, B; Singlas, E; Vachon, F; Wolff, M, 1989)
" We diagnosed Legionnaires' pneumonia accompanied by clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS), and started treatment with ciprofloxacin and methylprednisolone at 1 mg/kg/day."3.77[A case of Legionnaires' pneumonia accompanied by clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) with transient altered mental status and cerebellar symptoms, which responded to treatment by antibiotics and corticoste ( Akazawa, K; Hibi, M; Hibino, M; Hikino, K; Oe, M, 2011)
"The penetration of ofloxacin was studied in 22 patients with purulent meningitis or ventriculitis treated with conventional antibiotics."3.67Diffusion of ofloxacin into cerebrospinal fluid of patients with purulent meningitis or ventriculitis. ( Clair, B; Laisne, MJ; Pioget, JC; Regnier, B; Singlas, E; Vachon, F; Wolff, M, 1989)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hibino, M1
Hibi, M1
Akazawa, K1
Hikino, K1
Oe, M1
Pioget, JC1
Wolff, M1
Singlas, E1
Laisne, MJ1
Clair, B1
Regnier, B1
Vachon, F1

Other Studies

2 other studies available for ofloxacin and Brain Inflammation

ArticleYear
[A case of Legionnaires' pneumonia accompanied by clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) with transient altered mental status and cerebellar symptoms, which responded to treatment by antibiotics and corticoste
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2011, Volume: 49, Issue:9

    Topics: Adrenal Cortex Hormones; Cerebellar Ataxia; Corpus Callosum; Encephalitis; Humans; Legionnaires' Dis

2011
Diffusion of ofloxacin into cerebrospinal fluid of patients with purulent meningitis or ventriculitis.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Aged; Cerebral Ventricles; Diffusion; Encephalitis; Female; Half-Life; Humans; Ma

1989