ofloxacin has been researched along with Brain Abscess in 5 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Brain Abscess: A circumscribed collection of purulent exudate in the brain, due to bacterial and other infections. The majority are caused by spread of infected material from a focus of suppuration elsewhere in the body, notably the PARANASAL SINUSES, middle ear (see EAR, MIDDLE); HEART (see also ENDOCARDITIS, BACTERIAL), and LUNG. Penetrating CRANIOCEREBRAL TRAUMA and NEUROSURGICAL PROCEDURES may also be associated with this condition. Clinical manifestations include HEADACHE; SEIZURES; focal neurologic deficits; and alterations of consciousness. (Adams et al., Principles of Neurology, 6th ed, pp712-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The therapeutic effects of nimodipine (CAS 66085-59-4) and ofloxacin (CAS 82419-36-1) were investigated against experimental brain abscess formation in rats." | 7.69 | Effects of nimodipine and ofloxacin on staphylococcal brain abscesses in rats. ( Ceviz, A; Ciçek, R; Gül, K; Inalöz, SS; Sanli, A; Sari, I, 1997) |
| "The therapeutic effects of nimodipine (CAS 66085-59-4) and ofloxacin (CAS 82419-36-1) were investigated against experimental brain abscess formation in rats." | 3.69 | Effects of nimodipine and ofloxacin on staphylococcal brain abscesses in rats. ( Ceviz, A; Ciçek, R; Gül, K; Inalöz, SS; Sanli, A; Sari, I, 1997) |
| "We describe multiple brain abscesses due to P." | 1.37 | Brain abscesses during Proteus vulgaris bacteremia. ( Bloch, J; Ferriby, D; Legout, L; Lemaire, X; Senneville, E; Yazdanpanah, Y, 2011) |
| "We report the 1st case of R." | 1.35 | Rhodococcus equi pulmonary-central nervous system syndrome: brain abscess in a patient on high-dose steroids--a case report and review of the literature. ( Roda, RH; Rosen, J; Timpone, J; Young, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roda, RH | 1 |
| Young, M | 1 |
| Timpone, J | 1 |
| Rosen, J | 1 |
| Bloch, J | 1 |
| Lemaire, X | 1 |
| Legout, L | 1 |
| Ferriby, D | 1 |
| Yazdanpanah, Y | 1 |
| Senneville, E | 1 |
| Fukuta, Y | 1 |
| Yildiz-Aktas, IZ | 1 |
| William Pasculle, A | 1 |
| Veldkamp, PJ | 1 |
| Gabriels, P | 1 |
| Joosen, H | 1 |
| Put, E | 1 |
| Verhaegen, J | 1 |
| Magerman, K | 1 |
| Cartuyvels, R | 1 |
| Ceviz, A | 1 |
| Inalöz, SS | 1 |
| Ciçek, R | 1 |
| Sari, I | 1 |
| Gül, K | 1 |
| Sanli, A | 1 |
1 review available for ofloxacin and Brain Abscess
| Article | Year |
|---|---|
Legionella micdadei prosthetic valve endocarditis complicated by brain abscess: case report and review of the literature.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteriological Techniques; Brain; Brain Abscess; Echocardiograp | 2012 |
4 other studies available for ofloxacin and Brain Abscess
| Article | Year |
|---|---|
Rhodococcus equi pulmonary-central nervous system syndrome: brain abscess in a patient on high-dose steroids--a case report and review of the literature.
Topics: Actinomycetales Infections; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents | 2009 |
Brain abscesses during Proteus vulgaris bacteremia.
Topics: Anti-Bacterial Agents; Antiphospholipid Syndrome; Bacteremia; Brain; Brain Abscess; Ceftriaxone; Com | 2011 |
Recurrent Rhodococcus equi infection with fatal outcome in an immunocompetent patient.
Topics: Actinomycetales Infections; Aged; Brain Abscess; Fatal Outcome; Female; Humans; Immunocompetence; Mi | 2006 |
Effects of nimodipine and ofloxacin on staphylococcal brain abscesses in rats.
Topics: Animals; Anti-Infective Agents; Brain Abscess; Calcium Channel Blockers; Male; Nimodipine; Ofloxacin | 1997 |