ofloxacin has been researched along with Bone Inflammation in 8 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the pharmacokinetic and pharmacodynamic parameters of levofloxacin and rifampicin in bone and joint infections." | 1.38 | Pharmacokinetic and dynamic study of levofloxacin and rifampicin in bone and joint infections. ( Bensalem, M; Bland, S; Bru, JP; Gaillat, J; Garraffo, R; Guillaume, M; Janssen, C, 2012) |
| "We report the occurrence of idiopathic intracranial hypertension in a patient treated with ofloxacin, a fluoroquinolone antimicrobial agent, for 16 months." | 1.29 | Idiopathic intracranial hypertension after ofloxacin treatment. ( Aimard, G; Croisile, B; Getenet, JC; Goudable, B; Grochowicki, M; Trillet, M; Vighetto, A, 1993) |
| "13 micrograms/ml for a dosage of 8." | 1.27 | [Our experience with ofloxacin in the treatment of osteoarticular infections]. ( Hermet, R; Levai, JP; Lopitaux, R; Sirot, J; Terver, S, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| El Samad, Y | 1 |
| Havet, E | 1 |
| Bentayeb, H | 1 |
| Olory, B | 1 |
| Canarelli, B | 1 |
| Lardanchet, JF | 1 |
| Douadi, Y | 1 |
| Rousseau, F | 1 |
| Lescure, FX | 1 |
| Mertl, P | 1 |
| Eb, F | 1 |
| Schmit, JL | 1 |
| Guillaume, M | 1 |
| Garraffo, R | 2 |
| Bensalem, M | 1 |
| Janssen, C | 1 |
| Bland, S | 1 |
| Gaillat, J | 1 |
| Bru, JP | 1 |
| Getenet, JC | 1 |
| Croisile, B | 1 |
| Vighetto, A | 1 |
| Grochowicki, M | 1 |
| Goudable, B | 1 |
| Aimard, G | 1 |
| Trillet, M | 1 |
| Vittver, V | 1 |
| Ketterl', R | 1 |
| Brouqui, P | 1 |
| Aubaniac, JM | 1 |
| Curvale, G | 1 |
| Groulier, P | 1 |
| Raoult, D | 1 |
| Lopitaux, R | 1 |
| Hermet, R | 1 |
| Sirot, J | 1 |
| Terver, S | 1 |
| Levai, JP | 1 |
| Bernard, E | 1 |
| Etesse, H | 1 |
| Giaume, F | 1 |
| Dellamonica, P | 1 |
| Ketterl, R | 1 |
| Beckurts, T | 1 |
| Stübinger, B | 1 |
| Claudi, B | 1 |
1 trial available for ofloxacin and Bone Inflammation
| Article | Year |
|---|---|
[Chronic osteitis--modern therapy].
Topics: Administration, Oral; Anti-Infective Agents; Chronic Disease; Drug Administration Schedule; Enteroba | 1996 |
7 other studies available for ofloxacin and Bone Inflammation
| Article | Year |
|---|---|
[Treatment of osteoarticular infections with clindamycin in adults].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bone Diseases; Clindamy | 2008 |
Pharmacokinetic and dynamic study of levofloxacin and rifampicin in bone and joint infections.
Topics: Adult; Aged; Anti-Bacterial Agents; Area Under Curve; Arthritis, Infectious; Body Mass Index; Discit | 2012 |
Idiopathic intracranial hypertension after ofloxacin treatment.
Topics: Acetazolamide; Adult; Femoral Fractures; Humans; Intracranial Pressure; Long-Term Care; Male; Ofloxa | 1993 |
[Treatment of osteo-articular infections with ofloxacin. Preliminary study].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Bone Diseases; Drug Therapy, Combi | 1989 |
[Our experience with ofloxacin in the treatment of osteoarticular infections].
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacterial Infections; Female; Hip Prosthesis; | 1988 |
[Bone infections: treatment by ofloxacin. Apropos of 10 cases].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Enterobacteriaceae Infections; | 1987 |
Ofloxacin treatment in the management of chronic osteitis.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteria; Chronic Disease; Female; Humans; Male; Microbial Sensi | 1987 |