ofloxacin has been researched along with Blepharitis in 7 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Blepharitis: Inflammation of the eyelids.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5% levofloxacin, with and without eyelid scrub, in patients with chronic blepharoconjunctivitis (CBC)." | 9.14 | A prospective study determining the efficacy of topical 0.5% levofloxacin on bacterial flora of patients with chronic blepharoconjunctivitis. ( He, L; Kampik, A; Kreutzer, TC; Mino de Kaspar, H; Nentwich, MM; Ta, CN; Yactayo-Miranda, Y, 2009) |
| "5% levofloxacin, with and without eyelid scrub, in patients with chronic blepharoconjunctivitis (CBC)." | 5.14 | A prospective study determining the efficacy of topical 0.5% levofloxacin on bacterial flora of patients with chronic blepharoconjunctivitis. ( He, L; Kampik, A; Kreutzer, TC; Mino de Kaspar, H; Nentwich, MM; Ta, CN; Yactayo-Miranda, Y, 2009) |
| "Ofloxacin treatment eradicated or controlled 85% (86/101) of the Gram positive and 89% (17/19) of the Gram negative organisms cultured, compared with 83% (103/124) and 78% (29/37), respectively, after gentamicin treatment." | 2.67 | Topical ofloxacin compared with gentamicin in the treatment of external ocular infection. Ofloxacin Study Group. ( Gwon, A, 1992) |
| "Ofloxacin was found as effective, safe, and comfortable as tobramycin in patients with external ocular infection and may provide earlier symptom relief." | 2.67 | Ofloxacin vs tobramycin for the treatment of external ocular infection. Ofloxacin Study Group II. ( Gwon, A, 1992) |
| "Patients with suspected bacterial ocular infections were evaluated for clinical improvement and were included in drug safety and comfort analyses." | 2.67 | Ofloxacin compared with chloramphenicol in the management of external ocular infection. ( Baig, H; Bron, AJ; Elkington, AR; Harden, A; Kirkby, GR; Leber, G; Leong, T; Neoh, C; Rizk, SN, 1991) |
| "Some marginal blepharitis is related to demodex, but this has not yet been reported in Japan." | 1.36 | [Demodex-related marginal blepharitis in Japan]. ( Ibrahim, O; Kawakita, T; Kawashima, M; Murato, D; Tsubota, K, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matsumoto, Y | 1 |
| Shigeno, Y | 1 |
| Sato, EA | 1 |
| Ibrahim, OM | 1 |
| Saiki, M | 1 |
| Negishi, K | 1 |
| Ogawa, Y | 1 |
| Dogru, M | 1 |
| Tsubota, K | 2 |
| Yactayo-Miranda, Y | 1 |
| Ta, CN | 1 |
| He, L | 1 |
| Kreutzer, TC | 1 |
| Nentwich, MM | 1 |
| Kampik, A | 1 |
| Mino de Kaspar, H | 1 |
| Kawakita, T | 1 |
| Kawashima, M | 1 |
| Ibrahim, O | 1 |
| Murato, D | 1 |
| Friedlaender, MH | 1 |
| Gwon, A | 2 |
| Bron, AJ | 1 |
| Leber, G | 1 |
| Rizk, SN | 1 |
| Baig, H | 1 |
| Elkington, AR | 1 |
| Kirkby, GR | 1 |
| Neoh, C | 1 |
| Harden, A | 1 |
| Leong, T | 1 |
5 trials available for ofloxacin and Blepharitis
| Article | Year |
|---|---|
A prospective study determining the efficacy of topical 0.5% levofloxacin on bacterial flora of patients with chronic blepharoconjunctivitis.
Topics: Administration, Topical; Anti-Bacterial Agents; Blepharitis; Chronic Disease; Colony Count, Microbia | 2009 |
Twice-a-day versus four-times-a-day ofloxacin treatment of external ocular infection.
Topics: Administration, Topical; Anti-Infective Agents; Bacteria; Blepharitis; Colony Count, Microbial; Conj | 1998 |
Topical ofloxacin compared with gentamicin in the treatment of external ocular infection. Ofloxacin Study Group.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Blepharitis; Conjunctivitis; Eye Infections | 1992 |
Ofloxacin vs tobramycin for the treatment of external ocular infection. Ofloxacin Study Group II.
Topics: Blepharitis; Colony Count, Microbial; Conjunctiva; Conjunctivitis, Bacterial; Corneal Ulcer; Double- | 1992 |
Ofloxacin compared with chloramphenicol in the management of external ocular infection.
Topics: Adult; Aged; Aged, 80 and over; Blepharitis; Chloramphenicol; Conjunctivitis; Double-Blind Method; E | 1991 |
2 other studies available for ofloxacin and Blepharitis
| Article | Year |
|---|---|
The evaluation of the treatment response in obstructive meibomian gland disease by in vivo laser confocal microscopy.
Topics: Administration, Oral; Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents | 2009 |
[Demodex-related marginal blepharitis in Japan].
Topics: Adult; Aged; Animals; Blepharitis; Eyelashes; Female; Hair Follicle; Humans; Japan; Male; Middle Age | 2010 |