ofloxacin has been researched along with Bleb in 9 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report a case of spontaneous bleb formation in a presumed pellucid marginal corneal degeneration with acute hydrops." | 1.39 | Spontaneous bleb formation in a presumed pellucid marginal corneal degeneration with acute hydrops. ( Higashiura, R; Inoue, T; Maeda, N; Ohashi, Y; Suzuki, T; Toriyama, K, 2013) |
| "Ofloxacin was measured by a high-performance liquid chromatographic assay." | 1.28 | Multiple-dose pharmacokinetics of ofloxacin in serum, saliva, and skin blister fluid of healthy volunteers. ( Korting, HC; Mutschler, E; Schäfer-Korting, M; Warlich, R, 1990) |
| "A study was made of the plasma and distribution kinetics of ofloxacin administered at a dosage of 400 mg orally to a group of healthy volunteers and a group of patients with renal impairment." | 1.28 | Effect of renal impairment on distribution of ofloxacin. ( Domínguez-Gil Hurlé, A; Gomez Sanchez, JC; Martinez Lanao, J; Sanchez Navarro, A; Sanchez Recio, MM; Tabernero Romo, JM; Terreiro Delgado, MM, 1990) |
| " The mean serum elimination half-life was 7 h and 80." | 1.27 | The pharmacokinetics and tissue penetration of ofloxacin. ( Dent, J; Lockley, MR; Wise, R, 1984) |
| " The elimination half-life was 9." | 1.27 | Ofloxacin: serum and skin blister fluid pharmacokinetics in the fasting and non-fasting state. ( Bergan, T; Digranes, A; Kalager, T; Rolstad, T, 1986) |
| "In the fluid of dermal blisters produced by suction, the peak value was 1." | 1.27 | [Transfer of ofloxacin into suction blister fluid after its oral administration]. ( Aoyama, H; Ishii, T; Kasuya, T; Kawauchi, T; Nishizaki, A; Okuda, J; Sugiyama, H, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Toriyama, K | 1 |
| Inoue, T | 2 |
| Suzuki, T | 1 |
| Higashiura, R | 1 |
| Maeda, N | 1 |
| Ohashi, Y | 1 |
| Hisamori, S | 1 |
| Oida, K | 1 |
| Taguchi, Y | 1 |
| Tanaka, E | 1 |
| Katoh, K | 1 |
| Sakuramoto, M | 1 |
| Minaguchi, M | 1 |
| Maeda, Y | 1 |
| Maniwa, K | 1 |
| Terada, K | 1 |
| Ishimaru, H | 1 |
| Hata, K | 1 |
| Lockley, MR | 1 |
| Wise, R | 1 |
| Dent, J | 1 |
| Kawada, A | 1 |
| Hiruma, M | 1 |
| Noguchi, H | 1 |
| Banba, K | 1 |
| Ishibashi, A | 1 |
| Banba, H | 1 |
| Marshall, J | 1 |
| Trampuz, A | 1 |
| Wenk, M | 1 |
| Rajacic, Z | 1 |
| Zimmerli, W | 1 |
| Warlich, R | 1 |
| Korting, HC | 1 |
| Schäfer-Korting, M | 1 |
| Mutschler, E | 1 |
| Sanchez Navarro, A | 1 |
| Martinez Lanao, J | 1 |
| Sanchez Recio, MM | 1 |
| Domínguez-Gil Hurlé, A | 1 |
| Tabernero Romo, JM | 1 |
| Gomez Sanchez, JC | 1 |
| Terreiro Delgado, MM | 1 |
| Kalager, T | 1 |
| Digranes, A | 1 |
| Bergan, T | 1 |
| Rolstad, T | 1 |
| Aoyama, H | 1 |
| Sugiyama, H | 1 |
| Ishii, T | 1 |
| Kawauchi, T | 1 |
| Kasuya, T | 1 |
| Nishizaki, A | 1 |
| Okuda, J | 1 |
9 other studies available for ofloxacin and Bleb
| Article | Year |
|---|---|
Spontaneous bleb formation in a presumed pellucid marginal corneal degeneration with acute hydrops.
Topics: Acute Disease; Anti-Bacterial Agents; Aqueous Humor; Blister; Combined Modality Therapy; Corneal Dis | 2013 |
[A case of pulmonaly bulla infection with Mycobacterium fortuitum].
Topics: Aged; Blister; Cilastatin; Cilastatin, Imipenem Drug Combination; Clarithromycin; Drug Combinations; | 2003 |
The pharmacokinetics and tissue penetration of ofloxacin.
Topics: Adult; Anti-Infective Agents; Blister; Half-Life; Humans; Kinetics; Male; Ofloxacin; Oxazines | 1984 |
Fixed drug eruption induced by ofloxacin.
Topics: Anti-Infective Agents; Blister; Ciprofloxacin; Drug Eruptions; Erythema; Female; Foot Dermatoses; Ha | 1996 |
Pharmacokinetics and pharmacodynamics of levofloxacin against Streptococcus pneumoniae and Staphylococcus aureus in human skin blister fluid.
Topics: Anti-Infective Agents; Blister; Body Fluids; Granulocytes; Humans; Levofloxacin; Microbial Sensitivi | 2000 |
Multiple-dose pharmacokinetics of ofloxacin in serum, saliva, and skin blister fluid of healthy volunteers.
Topics: Adult; Blister; Body Fluids; Female; Half-Life; Humans; Male; Ofloxacin; Saliva | 1990 |
Effect of renal impairment on distribution of ofloxacin.
Topics: Adult; Blister; Extracellular Space; Humans; Kidney; Kidney Diseases; Ofloxacin | 1990 |
Ofloxacin: serum and skin blister fluid pharmacokinetics in the fasting and non-fasting state.
Topics: Adult; Blister; Body Fluids; Fasting; Female; Humans; Kinetics; Ofloxacin; Oxazines | 1986 |
[Transfer of ofloxacin into suction blister fluid after its oral administration].
Topics: Administration, Oral; Adult; Blister; Exudates and Transudates; Humans; Male; Middle Aged; Ofloxacin | 1987 |