Page last updated: 2024-11-01

ofloxacin and Bilirubinemia

ofloxacin has been researched along with Bilirubinemia in 2 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"Grepafloxacin (GPFX) has a comparatively greater hepatobiliary transport than other quinolone antibiotics."1.30Carrier-mediated mechanism for the biliary excretion of the quinolone antibiotic grepafloxacin and its glucuronide in rats. ( Sasabe, H; Sugiyama, Y; Tsuji, A, 1998)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sasabe, H1
Tsuji, A1
Sugiyama, Y1
Pubill-Fondevila, N1
Bielsa, S1
Porcel, JM1

Other Studies

2 other studies available for ofloxacin and Bilirubinemia

ArticleYear
Carrier-mediated mechanism for the biliary excretion of the quinolone antibiotic grepafloxacin and its glucuronide in rats.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:3

    Topics: Animals; Anti-Infective Agents; Bile; Biological Transport, Active; Fluoroquinolones; Glucuronates;

1998
[Levofloxacin hepatotoxicity].
    Medicina clinica, 2013, Mar-16, Volume: 140, Issue:6

    Topics: Adult; Alanine Transaminase; Anti-Bacterial Agents; Aspartate Aminotransferases; Bronchiectasis; Bro

2013