ofloxacin has been researched along with Bacteriuria in 31 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Bacteriuria: The presence of bacteria in the urine which is normally bacteria-free. These bacteria are from the URINARY TRACT and are not contaminants of the surrounding tissues. Bacteriuria can be symptomatic or asymptomatic. Significant bacteriuria is an indicator of urinary tract infection.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a prospective randomized study ofloxacin (400 mg orally once daily) versus co-trimoxazole (320/1,600 mg orally once daily) were given for 3 weeks in 30 and 22 elderly semimobile patients respectively, suffering from asymptomatic bacteriuria." | 9.07 | Kinetics and comparative efficacy of ofloxacin versus co-trimoxazole in the asymptomatic bacteriuria of elderly subjects. ( Dontas, A; Giamarellou, H; Iakovou, M; Petrikkos, G; Pistoni, M; Sfikakis, P, 1991) |
| "In order to reduce the dosage of aminoglycoside in the treatment of patients with complicated urinary tract infections (UTI) in outpatient clinics and to improve cost benefits, we tried both ofloxacin (OFX) treatment and a combination treatment with OFX and a single dose of aminoglycoside (isepamicin)." | 9.07 | Treatment of complicated urinary tract infections with ofloxacin following an aminoglycoside. ( Eto, K; Ishii, T; Kumazawa, J; Matsumoto, T; Saito, Y; Sawae, Y; Ueda, S; Yushita, Y, 1991) |
| "The efficacies of ofloxacin and norfloxacin in the treatment of chronic complicated urinary tract infections were compared." | 9.06 | Open randomised comparison of ofloxacin and norfloxacin in the treatment of complicated urinary tract infections. ( Rugendorff, EW, 1987) |
| "In a prospective study, 70 men suffering from uncomplicated acute unilateral epididymitis were treated initially with 2 x 200 mg ofloxacin p." | 7.68 | [Initial therapy of acute unilateral epididymitis using ofloxacin. I. Clinical and microbiological findings]. ( Friedrich, HJ; Garbe, C; Harbrecht, J; Kleinschmidt, K; Schiefer, HG; Weidner, W; Weissbach, L, 1990) |
| "The objective of this multicenter, randomized, controlled, parallel group trial was to evaluate the efficacy of levofloxacin 250 mg oral, once daily (LVFX), placebo one tablet oral once daily (Placebo [P] group) and ciprofloxacin (CPFX) 500 mg oral, twice daily (single blind), prophylaxis in preventing bacteriuria (> or = 10(3) CFU/ml) in post-surgical catheterized patients." | 5.12 | A pilot study on prevention of catheter-related urinary tract infections with fluoroquinolones. ( Drago, L; Esposito, S; Leone, S; Marchetti, F; Marvaso, A; Noviello, S, 2006) |
| " Overall bacteriuria rate at day 5 to 7 was 22% (levofloxacin 21%; TMP/SMZ 20%; control group 30%)." | 5.11 | Prospective, randomized, multicentric, open, comparative study on the efficacy of a prophylactic single dose of 500 mg levofloxacin versus 1920 mg trimethoprim/sulfamethoxazole versus a control group in patients undergoing TUR of the prostate. ( Naber, KG; Schinzel, S; Wagenlehner, C; Wagenlehner, FM, 2005) |
| "In a prospective randomized study ofloxacin (400 mg orally once daily) versus co-trimoxazole (320/1,600 mg orally once daily) were given for 3 weeks in 30 and 22 elderly semimobile patients respectively, suffering from asymptomatic bacteriuria." | 5.07 | Kinetics and comparative efficacy of ofloxacin versus co-trimoxazole in the asymptomatic bacteriuria of elderly subjects. ( Dontas, A; Giamarellou, H; Iakovou, M; Petrikkos, G; Pistoni, M; Sfikakis, P, 1991) |
| "In order to reduce the dosage of aminoglycoside in the treatment of patients with complicated urinary tract infections (UTI) in outpatient clinics and to improve cost benefits, we tried both ofloxacin (OFX) treatment and a combination treatment with OFX and a single dose of aminoglycoside (isepamicin)." | 5.07 | Treatment of complicated urinary tract infections with ofloxacin following an aminoglycoside. ( Eto, K; Ishii, T; Kumazawa, J; Matsumoto, T; Saito, Y; Sawae, Y; Ueda, S; Yushita, Y, 1991) |
| "The efficacies of ofloxacin and norfloxacin in the treatment of chronic complicated urinary tract infections were compared." | 5.06 | Open randomised comparison of ofloxacin and norfloxacin in the treatment of complicated urinary tract infections. ( Rugendorff, EW, 1987) |
| "Strains isolated in health-related bacteriuria are more frequently ofloxacin resistant principally because of the greater proportion of Gram positive bacteria and because of a non-significant higher ofloxacin resistance rate among Enterobacteriaceae." | 3.78 | [Differences between species involved and fluoroquinolone resistance patterns of strains isolated from bacteriuria according to nosocomial, health-related or community-acquired onset]. ( Batalla, AS; De Champs, C; Duval, V; Guillard, T; N'Guyen, Y; Strady, C; Tassain, J, 2012) |
| "In a prospective study, 70 men suffering from uncomplicated acute unilateral epididymitis were treated initially with 2 x 200 mg ofloxacin p." | 3.68 | [Initial therapy of acute unilateral epididymitis using ofloxacin. I. Clinical and microbiological findings]. ( Friedrich, HJ; Garbe, C; Harbrecht, J; Kleinschmidt, K; Schiefer, HG; Weidner, W; Weissbach, L, 1990) |
| "In the group of the patients with wound infection complicated by respiratory or urinary tract infection the clinical and bacteriological efficacies equaled 94-100 per cent." | 1.29 | [Ten-year experience with the use of ofloxacin in the treatment of wound infection]. ( Blatun, LA; Iakovlev, VP; Izotova, GN; Puchkova, LS; Svetukhin, AM, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (16.13) | 18.7374 |
| 1990's | 14 (45.16) | 18.2507 |
| 2000's | 11 (35.48) | 29.6817 |
| 2010's | 1 (3.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tassain, J | 1 |
| N'Guyen, Y | 1 |
| Batalla, AS | 1 |
| Duval, V | 1 |
| Guillard, T | 1 |
| De Champs, C | 1 |
| Strady, C | 1 |
| Doğan, HS | 1 |
| Sahin, A | 1 |
| Cetinkaya, Y | 1 |
| Akdoğan, B | 1 |
| Ozden, E | 1 |
| Kendi, S | 1 |
| Meiland, R | 1 |
| Geerlings, SE | 1 |
| De Neeling, AJ | 1 |
| Hoepelman, AI | 1 |
| Wagenlehner, FM | 1 |
| Wagenlehner, C | 1 |
| Schinzel, S | 1 |
| Naber, KG | 2 |
| Esposito, S | 1 |
| Noviello, S | 1 |
| Leone, S | 1 |
| Marvaso, A | 1 |
| Drago, L | 1 |
| Marchetti, F | 1 |
| Topkaya, AE | 1 |
| Ozakkaş, F | 1 |
| Aksungar, FB | 1 |
| Tülbek, Y | 1 |
| Giamarellou, H | 4 |
| Dontas, AS | 2 |
| Petrikkos, G | 4 |
| Gnardellis, C | 1 |
| Zorbas, P | 3 |
| Philippou, P | 1 |
| Ilker, Y | 1 |
| Türkeri, LN | 1 |
| Korten, V | 1 |
| Tarcan, T | 1 |
| Akdaş, A | 1 |
| Amyes, SG | 1 |
| Baird, DR | 1 |
| Crook, DW | 1 |
| Gillespie, SH | 1 |
| Howard, AJ | 1 |
| Oppenhiem, BA | 1 |
| Pedler, SJ | 1 |
| Paull, A | 1 |
| Tompkins, DS | 1 |
| Lawrie, SA | 1 |
| Morimoto, S | 1 |
| Hirano, A | 1 |
| Ohkawa, T | 1 |
| Doi, J | 1 |
| Suzuki, A | 1 |
| Hagino, K | 1 |
| Kitamura, S | 1 |
| Sawada, Y | 1 |
| Morita, T | 1 |
| Miyazaki, Y | 1 |
| Fica, AE | 1 |
| Horowitz, HW | 1 |
| Lior, H | 1 |
| Cabello, FC | 1 |
| Tatlişen, A | 1 |
| Carpinlioğlu, M | 1 |
| Sümerkan, B | 1 |
| Gülmez, I | 1 |
| Karacagil, M | 1 |
| Kawada, Y | 1 |
| Lee, SE | 1 |
| Chen, C | 1 |
| Limson, BM | 1 |
| Chan, P | 1 |
| Kongkanand, A | 1 |
| Wudhikarn, S | 1 |
| Tung, KH | 1 |
| Rahardjo, P | 1 |
| Saito, I | 1 |
| Staszewska-Pistoni, M | 2 |
| Grammatikou, M | 1 |
| Dontas, AJ | 1 |
| Blatun, LA | 1 |
| Iakovlev, VP | 1 |
| Svetukhin, AM | 1 |
| Puchkova, LS | 1 |
| Izotova, GN | 1 |
| Potts, JM | 1 |
| Ward, AM | 1 |
| Rackley, RR | 1 |
| Fujita, K | 1 |
| Mizuno, T | 1 |
| Ushiyama, T | 1 |
| Suzuki, K | 1 |
| Hadano, S | 1 |
| Satoh, S | 1 |
| Kambayashi, T | 1 |
| Mugiya, S | 1 |
| Nakano, M | 1 |
| Raz, R | 1 |
| Okev, N | 1 |
| Kennes, Y | 1 |
| Gilboa, A | 1 |
| Lavi, I | 1 |
| Bisharat, N | 1 |
| Nickel, JC | 1 |
| Downey, J | 1 |
| Johnston, B | 1 |
| Clark, J | 1 |
| Trinchieri, A | 1 |
| Mangiarotti, B | 1 |
| Lizzano, R | 1 |
| Kumazawa, J | 2 |
| Matsumoto, T | 2 |
| Iakovou, M | 1 |
| Pistoni, M | 1 |
| Dontas, A | 1 |
| Sfikakis, P | 1 |
| Ueda, S | 1 |
| Eto, K | 1 |
| Yushita, Y | 1 |
| Saito, Y | 1 |
| Ishii, T | 1 |
| Sawae, Y | 1 |
| Weidner, W | 1 |
| Garbe, C | 1 |
| Weissbach, L | 1 |
| Harbrecht, J | 1 |
| Kleinschmidt, K | 1 |
| Schiefer, HG | 1 |
| Friedrich, HJ | 1 |
| Thyroff-Friesinger, U | 1 |
| Langsádl, L | 1 |
| Menkyna, R | 1 |
| Golier, J | 1 |
| Silan, L | 1 |
| el-Baz, W | 1 |
| Osman, L | 1 |
| Abd-el-Hamid, T | 1 |
| el-Bokl, M | 1 |
| Sabbour, MS | 1 |
| Soriano, F | 1 |
| Ponte, C | 1 |
| Santamaría, M | 1 |
| Torres, A | 1 |
| Fernández-Roblas, R | 1 |
| Rugendorff, EW | 1 |
| Grima, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neutrophil and Lymphocyte Counts and the Neutrophil-to-lymphocyte Ratio as a Predictor of Fever Following Percutaneous Nephrolithotomy in Patients Without Risk Factors[NCT03774940] | 519 participants (Actual) | Interventional | 2005-01-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ofloxacin and Bacteriuria
| Article | Year |
|---|---|
[Use of levofloxacin in the antibiotic prophylaxis for diagnostic procedures in urology].
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Urinar | 2002 |
15 trials available for ofloxacin and Bacteriuria
| Article | Year |
|---|---|
Antibiotic prophylaxis in percutaneous nephrolithotomy: prospective study in 81 patients.
Topics: Adult; Antibiotic Prophylaxis; Bacteriuria; Dose-Response Relationship, Drug; Drug Administration Sc | 2002 |
Prospective, randomized, multicentric, open, comparative study on the efficacy of a prophylactic single dose of 500 mg levofloxacin versus 1920 mg trimethoprim/sulfamethoxazole versus a control group in patients undergoing TUR of the prostate.
Topics: Aged; Anti-Infective Agents; Anti-Infective Agents, Urinary; Antibiotic Prophylaxis; Bacteriuria; Dr | 2005 |
A pilot study on prevention of catheter-related urinary tract infections with fluoroquinolones.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; | 2006 |
Survival of elderly bacteriuric subjects following long-term quinolone therapy.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Bacteriuria; Female; Greece; Homes for the | 2007 |
Antimicrobial prophylaxis in management of urinary tract stones by extracorporeal shock-wave lithotripsy: is it necessary?
Topics: Adult; Bacteriuria; Female; Humans; Incidence; Kidney Calculi; Lithotripsy; Male; Ofloxacin; Premedi | 1995 |
[Clinical study on antimicrobial prophylaxis following extracorporeal shock wave lithotripsy].
Topics: Adult; Bacteriuria; Cephalosporins; Female; Humans; Lithotripsy; Male; Middle Aged; Ofloxacin; Preme | 1995 |
Evaluation of clinical efficacy of antimicrobials in complicated urinary tract infections. Comparison of Japanese criteria with IDSA guidelines. Infectious Diseases Society of America.
Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Bacteriuria; Female; Gram-Negative Bacteria; | 1995 |
Effectiveness of ofloxacin therapy in preventing functional impairment and increased mortality in elderly patients with bacteriuria.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Bacteriuria; Female; Humans; Male; Ofloxacin | 1995 |
Comparison of 2 oral ofloxacin regimens for the treatment of bacteriuria in elderly subjects.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Bacteriuria; Escherichia coli; Female; Humans; Male; | 1995 |
Complicating risk factors for pyelonephritis after extracorporeal shock wave lithotripsy.
Topics: Adolescent; Adult; Age Distribution; Aged; Anti-Infective Agents, Urinary; Bacteriuria; Humans; Kidn | 2000 |
Predictors of patient response to antibiotic therapy for the chronic prostatitis/chronic pelvic pain syndrome: a prospective multicenter clinical trial.
Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Antibodies, Bacterial; Bacteria; Bacterial In | 2001 |
Kinetics and comparative efficacy of ofloxacin versus co-trimoxazole in the asymptomatic bacteriuria of elderly subjects.
Topics: Aged; Aged, 80 and over; Ambulatory Care; Bacteriuria; Female; Humans; Male; Ofloxacin; Prospective | 1991 |
Treatment of complicated urinary tract infections with ofloxacin following an aminoglycoside.
Topics: Administration, Oral; Adolescent; Aged; Bacteriuria; Drug Therapy, Combination; Gentamicins; Humans; | 1991 |
Fosfomycin trometamol versus ofloxacin/co-trimoxazole as single dose therapy of acute uncomplicated urinary tract infection in females: a multicentre study.
Topics: Adolescent; Adult; Aged; Bacteriuria; Drug Administration Schedule; Drug Therapy, Combination; Drug | 1990 |
Open randomised comparison of ofloxacin and norfloxacin in the treatment of complicated urinary tract infections.
Topics: Adult; Anti-Infective Agents; Bacteriuria; Female; Humans; Male; Microbial Sensitivity Tests; Norflo | 1987 |
15 other studies available for ofloxacin and Bacteriuria
| Article | Year |
|---|---|
[Differences between species involved and fluoroquinolone resistance patterns of strains isolated from bacteriuria according to nosocomial, health-related or community-acquired onset].
Topics: Anti-Bacterial Agents; Bacteriuria; Community-Acquired Infections; Cross Infection; Drug Resistance, | 2012 |
Diabetes mellitus in itself is not a risk factor for antibiotic resistance in Escherichia coli isolated from patients with bacteriuria.
Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Infective Agents; Bacteriuria; Ciprofloxacin; Diabetes Co | 2004 |
[A case of urinary tract infection caused by Flavimonas oryzihabitans].
Topics: Anti-Infective Agents, Urinary; Bacteriuria; Carbapenems; Drug Resistance, Multiple, Bacterial; Fema | 2007 |
A multicentre study of the in-vitro activity of cefotaxime, cefuroxime, ceftazidime, ofloxacin and ciprofloxacin against blood and urinary pathogens.
Topics: Anti-Infective Agents; Bacteremia; Bacteria; Bacteriuria; Cefotaxime; Ceftazidime; Cefuroxime; Cepha | 1994 |
Demonstration of persistence of Salmonella typhimurium in an AIDS patient by molecular methods.
Topics: Adult; AIDS-Related Opportunistic Infections; Bacteriophage Typing; Bacteriuria; Diarrhea; DNA Trans | 1994 |
[Evaluation of 18 epididymo-orchitis cases].
Topics: Adolescent; Adult; Bacteriuria; Brucellosis; Doxycycline; Drug Therapy, Combination; Epididymitis; E | 1993 |
[Ten-year experience with the use of ofloxacin in the treatment of wound infection].
Topics: Administration, Oral; Anti-Infective Agents; Bacteriuria; Drug Administration Schedule; Humans; Infu | 1996 |
Association of chronic urinary symptoms in women and Ureaplasma urealyticum.
Topics: Adolescent; Adult; Aged; Azithromycin; Bacteriological Techniques; Bacteriuria; Chronic Disease; Cys | 2000 |
Demographic characteristics of patients with community-acquired bacteriuria and susceptibility of urinary pathogens to antimicrobials in northern Israel.
Topics: Adolescent; Adult; Aged; Amoxicillin; Bacteriuria; Cephalexin; Child; Child, Preschool; Community-Ac | 2000 |
The dipstick test in the diagnosis of UTI and the effect of pretreatment catheter exchange in catheter-associated UTI.
Topics: Bacteriuria; Esterases; Evaluation Studies as Topic; Humans; Japan; Leukocyte Count; Levofloxacin; N | 1992 |
[Initial therapy of acute unilateral epididymitis using ofloxacin. I. Clinical and microbiological findings].
Topics: Acute Disease; Adult; Bacterial Infections; Bacteriuria; Chlamydia trachomatis; Epididymitis; Follow | 1990 |
[Comparison of the antibacterial effects of ofloxacin, oxolinic acid and nalidixic acid].
Topics: Anti-Bacterial Agents; Bacteriuria; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Nalidix | 1988 |
Ofloxacin therapy of difficult-to-treat infections due to multiresistant organisms.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bacteriuria; Drug Re | 1987 |
Susceptibility of urinary isolates of Corynebacterium group D2 to fifteen antimicrobials and acetohydroxamic acid.
Topics: Anti-Bacterial Agents; Bacteriuria; Corynebacterium; Humans; Hydrogen-Ion Concentration; Hydroxamic | 1987 |
Ofloxacin: in-vitro activity against clinical isolates.
Topics: Bacteriuria; Drug Resistance, Microbial; Enterobacter; Enterobacteriaceae; Microbial Sensitivity Tes | 1985 |