Page last updated: 2024-11-01

ofloxacin and Atypical Mycobacterial Infection, Disseminated

ofloxacin has been researched along with Atypical Mycobacterial Infection, Disseminated in 42 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"The case experienced pyothorax due to pulmonary tuberculosis three years before and Mycobacterium avium pleuritis one year before this episode."1.35[Case of pneumothorax associated with pulmonary Mycobacterium fortuitum infection]. ( Baba, T; Endo, T; Hagiwara, E; Komatsu, S; Matsumoto, Y; Nishihira, R; Ogura, T; Sato, T; Sekine, A; Shinohara, T; Sogo, Y; Takahashi, H, 2008)
"Clarithromycin (CAM) was started for M."1.33[A case of Mycobacterium fortuitum meningitis following surgery for meningioma]. ( Eguchi, K; Fujikawa, K; Fukuda, T; Motomura, M; Ooe, N; Suenaga, A, 2006)
"Linezolid was more active against M."1.32In vitro activity of new fluoroquinolones and linezolid against non-tuberculous mycobacteria. ( López, M; Rodriguez Díaz, JC; Royo, G; Ruiz, M, 2003)
"We report a case of Mycobacterium abscessus infection complicated with diabetes mellitus."1.31[Mycobacterium abscessus infection complicated with diabetes mellitus]. ( Harada, H; Iwasaki, Y; Minagawa, T; Nagata, K; Nakagawa, M; Nakanishi, M; Natsuhara, A; Takemura, Y, 2002)
" These laboratory results concur with our experience of the efficacy of once-daily dosing with these drugs in the treatment of infections caused by M."1.29Postantibiotic effects of amikacin and ofloxacin on Mycobacterium fortuitum. ( Chan, CY; Cheng, AF; Li, MS; Tsui, SY; Yew, WW, 1993)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19906 (14.29)18.7374
1990's12 (28.57)18.2507
2000's18 (42.86)29.6817
2010's5 (11.90)24.3611
2020's1 (2.38)2.80

Authors

AuthorsStudies
Flores-Suárez, LF1
Fernández-Sánchez, M1
Ahumada-Topete, VH1
Rodríguez, M1
Charli-Joseph, Y1
Dabas, G1
Sharma, K1
Narang, T1
Sharma, M1
Chatterjee, D1
Dogra, S1
Chen, HW1
Lai, CC1
Tan, CK1
Lin, JN1
Lai, CH1
Chen, YH1
Huang, CK1
Lin, HF1
Eng, HL1
Lin, HH1
Sawahata, M1
Hagiwara, E2
Ogura, T2
Komatsu, S2
Sekine, A2
Tsuchiya, N1
Takahashi, H2
Ota, R1
Iwasawa, MT1
Ohkusu, K1
Kambe, N1
Matsue, H1
Omoruyi, OJ1
Ip, WY1
Fung, BK1
Kobashi, Y1
Mouri, K1
Obase, Y1
Kato, S1
Oka, M1
Fujita, N1
Utani, A1
Matsumoto, F1
Matsushima, H1
Kakuta, M1
Hatamochi, A1
Shinkai, H1
Dauendorffer, JN1
Laurain, C1
Weber, M1
Dailloux, M1
Rodriguez Díaz, JC1
López, M1
Ruiz, M1
Royo, G1
Hisamori, S1
Oida, K1
Taguchi, Y1
Tanaka, E1
Inoue, T1
Katoh, K1
Sakuramoto, M1
Minaguchi, M1
Maeda, Y1
Maniwa, K1
Terada, K1
Ishimaru, H1
Hata, K1
Bormann, G1
Marsch, WC1
Sarayba, MA1
Shamie, N1
Reiser, BJ1
Sweet, PM1
Taban, M1
Graff, JM1
Kesler-Diaz, A1
Osann, KE1
McDonnell, PJ1
Caballero, AR1
Marquart, ME1
O'Callaghan, RJ1
Thibodeaux, BA1
Johnston, KH1
Dajcs, JJ1
Shitrit, D1
Baum, GL1
Priess, R1
Lavy, A1
Shitrit, AB1
Raz, M1
Shlomi, D1
Daniele, B1
Kramer, MR1
Nakagawa, K1
Tsuruta, D1
Ishii, M1
Fujikawa, K1
Suenaga, A1
Motomura, M1
Fukuda, T1
Ooe, N1
Eguchi, K1
Serra, C1
Loi, G1
Saddi, B1
Pautasso, M1
Manzin, A1
Sato, T1
Baba, T1
Shinohara, T1
Endo, T1
Sogo, Y1
Nishihira, R1
Matsumoto, Y1
Moriuchi, R1
Arita, K1
Ujiie, H1
Kodama, K1
Shimizu, T1
Shimizu, H1
Tsui, SY1
Yew, WW5
Li, MS1
Chan, CY1
Cheng, AF1
Komachi, H1
Uchihara, T1
Saito, Y1
Takewaki, S1
Nagai, R1
Furukawa, T1
Iijima, S1
Saito, J1
Otsuka, F1
Fridolijn Jongevos, S1
Prens, EP1
Habets, JM1
de Jong, JJ1
van Gelder, T1
IJzermans, JN1
Endtz, HP1
Weimar, W1
Vacher, S1
Pellegrin, JL1
Leblanc, F1
Fourche, J1
Maugein, J1
Gillespie, SH1
Morrissey, I1
Everett, D1
Schreiber, J1
Burkhardt, U1
Rüsch-Gerdes, S1
Amthor, M1
Richter, E1
Zugehör, M1
Rosahl, W1
Ernst, M1
Takemura, Y1
Iwasaki, Y1
Minagawa, T1
Nakanishi, M1
Nagata, K1
Natsuhara, A1
Harada, H1
Nakagawa, M1
Zwoliński, J1
Gałazka, J1
Hasegawa, T1
Watanabe, R1
Hayashi, K1
Inufusa, A1
Nakagawa, H1
Tomioka, H2
Sato, K2
Saito, H2
Kwan, SY4
Wong, PC1
Lee, J1
Fujimoto, W1
Kanzaki, H1
Fujiwara, H1
Arata, J1
Ma, WK3
Lui, KS1
Suen, HC1
Heap, BJ1
Aung-khin, M1
Mok, CK2
Khin, MA1
Watanabe, T1
Tsukamura, M1
Kita, N1
Shimoide, H1
Yoshimoto, K1
Wada, T1
Mitani, Y1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Clarithromycin or Moxifloxacin Containing Regimen in 6 Months Sputum Conversion of Mycobacterium Xenopi[NCT01298336]Phase 392 participants (Actual)Interventional2011-03-02Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for ofloxacin and Atypical Mycobacterial Infection, Disseminated

ArticleYear
[Pulmonary mycobacteriosis caused by Mycobacterium peregrinum in a young, healthy man].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2010, Volume: 48, Issue:11

    Topics: Clarithromycin; Drug Therapy, Combination; Ethambutol; Humans; Levofloxacin; Male; Mycobacterium Inf

2010
[Cutaneous infection by Mycobacterium fortuitum biovariant "third group"--a case report and bacteriological examination of the isolate].
    Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1990, Volume: 100, Issue:11

    Topics: Adult; Anti-Bacterial Agents; Drug Resistance, Microbial; Female; Humans; Mycobacterium Infections,

1990

Other Studies

40 other studies available for ofloxacin and Atypical Mycobacterial Infection, Disseminated

ArticleYear
After all, still a magnificent impersonator.
    Rheumatology (Oxford, England), 2021, 07-01, Volume: 60, Issue:7

    Topics: Adult; Biopsy; Clofazimine; Diagnostic Errors; Female; Humans; Leprostatic Agents; Mycobacterium; My

2021
Cutaneous non-tubercular mycobacterial infection in pregnancy and treatment consideration.
    European journal of obstetrics, gynecology, and reproductive biology, 2019, Volume: 237

    Topics: Adult; Anti-Bacterial Agents; Female; Humans; Linezolid; Mycobacterium fortuitum; Mycobacterium Infe

2019
Arthritis caused by Mycobacterium terrae in a patient with rheumatoid arthritis.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2009, Volume: 13, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Arthritis, Rheumatoid; Azithromycin; Drug Therapy, Combination; Ethamb

2009
Urinary Mycobacterium szulgai infection in an immunocompetent patient.
    Southern medical journal, 2009, Volume: 102, Issue:9

    Topics: Antitubercular Agents; Drug Therapy, Combination; Female; Humans; Immunocompetence; Isoniazid; Levof

2009
Maximum growth temperature test for cutaneous Mycobacterium chelonae predicts the efficacy of thermal therapy.
    The Journal of dermatology, 2012, Volume: 39, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Colitis, Ulcerative; Humans; Hyperthermia, In

2012
Metachronous Mycobacterium terrae complex tenosynovitis of the hand.
    The Journal of hand surgery, European volume, 2012, Volume: 37, Issue:6

    Topics: Aged; Anti-Bacterial Agents; Blood Sedimentation; C-Reactive Protein; Clarithromycin; Hand; Histiocy

2012
Pulmonary Mycobacterium kyorinense disease showed clinical improvement following combined therapy with clarithromycin and levofloxacin.
    Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:14

    Topics: Anti-Bacterial Agents; Clarithromycin; Drug Therapy, Combination; Humans; Levofloxacin; Male; Microb

2012
Levofloxacin alone efficiently treated a cutaneous mycobacterium fortuitum infection.
    The Journal of dermatology, 2002, Volume: 29, Issue:7

    Topics: Administration, Oral; Adolescent; Anti-Infective Agents; Drug Administration Schedule; Female; Follo

2002
In vitro sensitivity of Mycobacterium xenopi to five antibiotics.
    Pathologie-biologie, 2002, Volume: 50, Issue:10

    Topics: Amikacin; Anti-Bacterial Agents; Clarithromycin; Ethambutol; Microbial Sensitivity Tests; Mycobacter

2002
In vitro activity of new fluoroquinolones and linezolid against non-tuberculous mycobacteria.
    International journal of antimicrobial agents, 2003, Volume: 21, Issue:6

    Topics: Acetamides; Anti-Bacterial Agents; Aza Compounds; Fluoroquinolones; Gatifloxacin; Humans; Levofloxac

2003
[A case of pulmonaly bulla infection with Mycobacterium fortuitum].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 2003, Volume: 77, Issue:6

    Topics: Aged; Blister; Cilastatin; Cilastatin, Imipenem Drug Combination; Clarithromycin; Drug Combinations;

2003
[Sporotrichoid atypical mycobacterial infections. Antibiotic monotherapy].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2004, Volume: 55, Issue:3

    Topics: Adult; Biopsy; Clarithromycin; Diagnosis, Differential; Drug Resistance, Multiple, Bacterial; Female

2004
Fluoroquinolone therapy in Mycobacterium chelonae keratitis after lamellar keratectomy.
    Journal of cataract and refractive surgery, 2005, Volume: 31, Issue:7

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Cornea; Corneal Transplantat

2005
Effectiveness of fluoroquinolones against Mycobacterium abscessus in vivo.
    Current eye research, 2006, Volume: 31, Issue:1

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Colony Count,

2006
Pulmonary Mycobacterium kansasii infection in Israel, 1999-2004: clinical features, drug susceptibility, and outcome.
    Chest, 2006, Volume: 129, Issue:3

    Topics: Adult; Antibiotics, Antitubercular; Ciprofloxacin; Clarithromycin; Cycloserine; Ethambutol; Ethionam

2006
Successful treatment of a widespread cutaneous Mycobacterium fortuitum infection with levofloxacin.
    International journal of dermatology, 2006, Volume: 45, Issue:9

    Topics: Adult; Anti-Bacterial Agents; Female; Humans; Levofloxacin; Mycobacterium; Mycobacterium fortuitum;

2006
[A case of Mycobacterium fortuitum meningitis following surgery for meningioma].
    Rinsho shinkeigaku = Clinical neurology, 2006, Volume: 46, Issue:7

    Topics: Clarithromycin; Female; Humans; Levofloxacin; Meningeal Neoplasms; Meningioma; Meningitis, Bacterial

2006
Unusual clinical presentation of Mycobacterium fortuitum infection in an immunocompetent woman.
    Journal of clinical microbiology, 2007, Volume: 45, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Female; Humans; Immunocompetence; Kidney Diseases; Mycobacterium fortu

2007
[Case of pneumothorax associated with pulmonary Mycobacterium fortuitum infection].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 2008, Volume: 82, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Clarithromycin; Combined Modality Therapy; Drainage; Drug Resistance,

2008
Large subcutaneous abscesses caused by Mycobacterium fortuitum infection.
    Acta dermato-venereologica, 2008, Volume: 88, Issue:3

    Topics: Abscess; Adult; Anti-Bacterial Agents; Female; Humans; Minocycline; Mycobacterium fortuitum; Mycobac

2008
Postantibiotic effects of amikacin and ofloxacin on Mycobacterium fortuitum.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:5

    Topics: Amikacin; Colony Count, Microbial; Culture Media; Drug Administration Schedule; Humans; Microbial Se

1993
Successful treatment of atypical mycobacterial meningitis by fluoroquinolone.
    Journal of the neurological sciences, 1996, Volume: 143, Issue:1-2

    Topics: Administration, Oral; Adult; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, An

1996
Mycobacterium marinum skin infection successfully treated with levofloxacin.
    Archives of dermatology, 1997, Volume: 133, Issue:8

    Topics: Adult; Anti-Infective Agents; Humans; Levofloxacin; Male; Mycobacterium Infections, Nontuberculous;

1997
Successful triple-antibiotic therapy for cutaneous infection due to Mycobacterium chelonae.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1999, Volume: 28, Issue:1

    Topics: Aged; Doxycycline; Drug Therapy, Combination; Ethambutol; Female; Humans; Mycobacterium chelonae; My

1999
Atypical mycobacterium infection with dermatological manifestation in a renal transplant recipient.
    Transplant international : official journal of the European Society for Organ Transplantation, 1999, Volume: 12, Issue:1

    Topics: Clarithromycin; Drug Therapy, Combination; Ethambutol; Foot; Humans; Kidney Transplantation; Male; M

1999
Comparative antimycobacterial activities of ofloxacin, ciprofloxacin and grepafloxacin.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 44, Issue:5

    Topics: Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Fluoroquinolones; Humans; Macrophages

1999
A comparison of the bactericidal activity of quinolone antibiotics in a Mycobacterium fortuitum model.
    Journal of medical microbiology, 2001, Volume: 50, Issue:6

    Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistan

2001
[Non-tubercular mycobacterial infection of the lungs due to Mycobacterium smegmatis].
    Pneumologie (Stuttgart, Germany), 2001, Volume: 55, Issue:5

    Topics: Cardiopulmonary Resuscitation; CD4-Positive T-Lymphocytes; Clarithromycin; Drug Therapy, Combination

2001
[Mycobacterium abscessus infection complicated with diabetes mellitus].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2002, Volume: 40, Issue:1

    Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Cilastatin; Cilastatin, Imipen

2002
[Ofloxacin in the treatment of pulmonary changes caused by Mycobacterium avium and Mycobacterium xenopii].
    Pneumonologia i alergologia polska, 1992, Volume: 60, Issue:5-6

    Topics: Humans; Male; Middle Aged; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection

1992
Postoperative osteomyelitis due to Mycobacterium fortuitum. A case report.
    Archives of orthopaedic and trauma surgery, 1992, Volume: 111, Issue:3

    Topics: Adolescent; Antitubercular Agents; Combined Modality Therapy; Drug Therapy, Combination; Fracture Fi

1992
Comparative in vitro and in vivo activity of fleroxacin and ofloxacin against various mycobacteria.
    Tubercle, 1991, Volume: 72, Issue:3

    Topics: Animals; Disease Models, Animal; Female; Fleroxacin; Leprosy; Mice; Mice, Inbred BALB C; Microbial S

1991
Ofloxacin and imipenem in the treatment of Mycobacterium fortuitum and Mycobacterium chelonae lung infections.
    Tubercle, 1990, Volume: 71, Issue:2

    Topics: Adult; Female; Humans; Imipenem; Male; Middle Aged; Mycobacterium Infections, Nontuberculous; Ofloxa

1990
Ofloxacin therapy of Mycobacterium fortuitum infection: further experience.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 25, Issue:5

    Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Mycobacterium Infections; Mycobacterium Infections,

1990
[Rifabutine in the treatment of mycobacterial infections resistant to rifampicin. Preliminary results. Group for the Study and Treatment of Resistant Mycobacterial Infections (GETIM)].
    Revue des maladies respiratoires, 1989, Volume: 6, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Drug Resistance, Microbial; Drug Therapy, Combinati

1989
Mycobacterium simiae as a cause of intra-abdominal disease: a case report.
    Tubercle, 1989, Volume: 70, Issue:3

    Topics: Abdomen; Adult; Ascitic Fluid; Drug Therapy, Combination; Female; Humans; Isoniazid; Kanamycin; Myco

1989
Combination of ofloxacin and amikacin in the treatment of sternotomy wound infection.
    Chest, 1989, Volume: 95, Issue:5

    Topics: Adult; Aged; Amikacin; Cardiac Surgical Procedures; Drug Combinations; Female; Humans; Injections, I

1989
Single daily-dose ofloxacin monotherapy for Mycobacterium fortuitum sternotomy infection.
    Chest, 1989, Volume: 96, Issue:5

    Topics: Drug Administration Schedule; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mycoba

1989
[In vitro and in vivo activities of norfloxacin, ofloxacin and ciprofloxacin against various mycobacteria].
    Kekkaku : [Tuberculosis], 1987, Volume: 62, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Female; Mice; Mycobacteri

1987
[Lung infections due to Mycobacterium fortuitum and Mycobacterium chelonae. Reports of nine cases of M. fortuitum infection and four cases of M. chelonae infection].
    Kekkaku : [Tuberculosis], 1985, Volume: 60, Issue:8

    Topics: Adolescent; Aged; Female; Humans; Male; Middle Aged; Mycobacterium Infections, Nontuberculous; Nontu

1985