Page last updated: 2024-11-01

ofloxacin and Arrhythmia

ofloxacin has been researched along with Arrhythmia in 4 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
" Evidence of association between exposure to drugs (erythromycin and ciprofloxacin) and the risk of arrhythmia was consistently found by the three approaches."3.73Generating signals of drug-adverse effects from prescription databases and application to the risk of arrhythmia associated with antibacterials. ( Bagnardi, V; Botteri, E; Carobbio, A; Corrao, G; Falcone, C; Leoni, O; Zambon, A, 2005)
"Levofloxacin was predominantly prescribed for treating community-acquired infections (67."1.32[Observational study investigating the use of levofloxacin in ICU patients]. ( Alvarez-Lerma, F; Bermejo, B; León, C; Olaechea, P; Palomar, M; Sánchez, M, 2004)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jia, L1
Sun, H1
Alvarez-Lerma, F1
Palomar, M1
Olaechea, P1
León, C1
Sánchez, M1
Bermejo, B1
Corrao, G1
Botteri, E1
Bagnardi, V1
Zambon, A1
Carobbio, A1
Falcone, C1
Leoni, O1
Clark, DW1
Layton, D1
Wilton, LV1
Pearce, GL1
Shakir, SA1

Other Studies

4 other studies available for ofloxacin and Arrhythmia

ArticleYear
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant

2008
[Observational study investigating the use of levofloxacin in ICU patients].
    Enfermedades infecciosas y microbiologia clinica, 2004, Volume: 22, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Arrhythmias, Cardiac; B

2004
Generating signals of drug-adverse effects from prescription databases and application to the risk of arrhythmia associated with antibacterials.
    Pharmacoepidemiology and drug safety, 2005, Volume: 14, Issue:1

    Topics: Adverse Drug Reaction Reporting Systems; Anti-Bacterial Agents; Arrhythmias, Cardiac; Case-Control S

2005
Profiles of hepatic and dysrhythmic cardiovascular events following use of fluoroquinolone antibacterials: experience from large cohorts from the Drug Safety Research Unit Prescription-Event Monitoring database.
    Drug safety, 2001, Volume: 24, Issue:15

    Topics: Adult; Aged; Anti-Infective Agents; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Ci

2001