Page last updated: 2024-11-01

ofloxacin and Anxiety

ofloxacin has been researched along with Anxiety in 2 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
") had no depression-like effect in the forced swimming test (FST) in rats; exerted anxiety-like effect in the elevated plus maze test in rats; did not alter the locomotor activity in rats; had no apparent effect on sleep latency but shortened the sleeping time on pentobarbital sleeping time in mice; and showed analgesic activity in acetic acid writhing and hot plate test in mice."3.71Antidepressant, anxiogenic, and antinociceptive properties of levofloxacin in rats and mice. ( Erden, BF; Gacar, N; Ozdemirci, S; Ulak, G; Utkan, T; Yildiz, F, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Prabhu, S1
Rewari, S1
Erden, BF1
Ulak, G1
Yildiz, F1
Utkan, T1
Ozdemirci, S1
Gacar, N1

Other Studies

2 other studies available for ofloxacin and Anxiety

ArticleYear
A comparative study of anxiogenic effects of fluoroquinolones in rats.
    Indian journal of physiology and pharmacology, 1998, Volume: 42, Issue:1

    Topics: Animals; Anti-Infective Agents; Anxiety; Ciprofloxacin; Female; Injections, Intraperitoneal; Male; O

1998
Antidepressant, anxiogenic, and antinociceptive properties of levofloxacin in rats and mice.
    Pharmacology, biochemistry, and behavior, 2001, Volume: 68, Issue:3

    Topics: Analgesics; Animals; Anti-Infective Agents; Antidepressive Agents; Anxiety; Hypnotics and Sedatives;

2001