ofloxacin has been researched along with Antibiotic-Associated Colitis in 13 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among hospitalized patients with diarrhea who underwent testing for C difficile toxin, age 75 years or older, hospitalization for 7 days or greater, and recent exposure to cefazolin or levofloxacin were important predictors of a positive CDTT." | 3.74 | Is it Clostridium difficile infection or something else? A case-control study of 352 hospitalized patients with new-onset diarrhea. ( Aradhyula, S; Greisnauer, S; Manian, FA; Meyer, PL; Senkel, D; Setzer, J; Wiechens, M, 2007) |
| "In this controlled before and after observational study, moxifloxacin chemoprophylaxis was used during prolonged neutropenia in haemato-oncological patients (period 2; 282 episodes)." | 3.73 | Moxifloxacin prophylaxis in neutropenic patients. ( Bommer, M; Döhner, H; Kern, P; Kern, WV; Marre, R; Reuter, S; Sigge, A; von Baum, H, 2006) |
| " Although very useful agents, the fluoroquinolones as a class are associated with a number of adverse events, some with considerable clinical significance." | 2.46 | Safety profile of the fluoroquinolones: focus on levofloxacin. ( Liu, HH, 2010) |
| "Patients who are treated for acute leukemia should be offered prophylaxis with ciprofloxacin or levofloxacin." | 2.43 | Antibiotic prophylaxis in neutropenic patients: new evidence, practical decisions. ( Bucaneve, G; Cullen, M; Fraser, A; Gafter-Gvili, A; Kern, WV; Leibovici, L; Paul, M, 2006) |
| "He had had recent chemotherapy for Merkel cell carcinoma of the right ear." | 1.34 | Use of intravenous immunoglobulin for the treatment of severe Clostridium difficile colitis. ( Hassoun, A; Ibrahim, F, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 7 (53.85) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, HH | 1 |
| Kawaratani, H | 1 |
| Tsujimoto, T | 1 |
| Toyohara, M | 1 |
| Kin, K | 1 |
| Taniguchi, T | 1 |
| Shirai, Y | 1 |
| Ikenaka, Y | 1 |
| Nakayama, M | 1 |
| Fujii, H | 1 |
| Fukui, H | 1 |
| Muto, CA | 1 |
| Pokrywka, M | 1 |
| Shutt, K | 1 |
| Mendelsohn, AB | 1 |
| Nouri, K | 1 |
| Posey, K | 1 |
| Roberts, T | 1 |
| Croyle, K | 1 |
| Krystofiak, S | 1 |
| Patel-Brown, S | 1 |
| Pasculle, AW | 1 |
| Paterson, DL | 1 |
| Saul, M | 1 |
| Harrison, LH | 1 |
| von Baum, H | 1 |
| Sigge, A | 1 |
| Bommer, M | 1 |
| Kern, WV | 2 |
| Marre, R | 1 |
| Döhner, H | 1 |
| Kern, P | 1 |
| Reuter, S | 1 |
| Dhalla, IA | 1 |
| Mamdani, MM | 1 |
| Simor, AE | 1 |
| Kopp, A | 1 |
| Rochon, PA | 1 |
| Juurlink, DN | 1 |
| Leibovici, L | 1 |
| Paul, M | 1 |
| Cullen, M | 1 |
| Bucaneve, G | 1 |
| Gafter-Gvili, A | 1 |
| Fraser, A | 1 |
| Biller, P | 1 |
| Shank, B | 1 |
| Lind, L | 1 |
| Brennan, M | 1 |
| Tkatch, L | 1 |
| Killgore, G | 1 |
| Thompson, A | 1 |
| McDonald, LC | 1 |
| Hassoun, A | 1 |
| Ibrahim, F | 1 |
| Manian, FA | 1 |
| Aradhyula, S | 1 |
| Greisnauer, S | 1 |
| Senkel, D | 1 |
| Setzer, J | 1 |
| Wiechens, M | 1 |
| Meyer, PL | 1 |
| Yew, WW | 1 |
| Chau, CH | 1 |
| Wen, KH | 1 |
| Roblin, X | 1 |
| Baudry, C | 1 |
| Becot, F | 1 |
| Abidaner, J | 1 |
| Monnet, D | 1 |
| Dan, M | 1 |
| Samra, Z | 1 |
| Tacke, W | 1 |
| Hausmann, L | 1 |
4 reviews available for ofloxacin and Antibiotic-Associated Colitis
| Article | Year |
|---|---|
Safety profile of the fluoroquinolones: focus on levofloxacin.
Topics: Adult; Aged, 80 and over; Anti-Bacterial Agents; Cardiovascular Diseases; Central Nervous System Dis | 2010 |
Pseudomembranous colitis complicating ulcerative colitis.
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Colitis, Ulcerative; Colonoscopy; Enterocolit | 2010 |
Antibiotic prophylaxis in neutropenic patients: new evidence, practical decisions.
Topics: Acute Disease; Antibiotic Prophylaxis; Antineoplastic Agents; Bone Marrow Transplantation; Ciproflox | 2006 |
[Pseudomembraneous colitis following antibiotic administration--a diagnostic and therapeutic challenge].
Topics: Aged; Anti-Bacterial Agents; Enterocolitis, Pseudomembranous; Female; Humans; Intestinal Mucosa; Mid | 1988 |
9 other studies available for ofloxacin and Antibiotic-Associated Colitis
| Article | Year |
|---|---|
A large outbreak of Clostridium difficile-associated disease with an unexpected proportion of deaths and colectomies at a teaching hospital following increased fluoroquinolone use.
Topics: Anti-Bacterial Agents; Case-Control Studies; Cause of Death; Clindamycin; Clostridioides difficile; | 2005 |
Moxifloxacin prophylaxis in neutropenic patients.
Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Aza Compounds; Bacteremia; Clostridioides difficile; | 2006 |
Are broad-spectrum fluoroquinolones more likely to cause Clostridium difficile-associated disease?
Topics: Aged; Aged, 80 and over; Aza Compounds; Case-Control Studies; Clostridioides difficile; Enterocoliti | 2006 |
Moxifloxacin therapy as a risk factor for Clostridium difficile-associated disease during an outbreak: attempts to control a new epidemic strain.
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Clostridioides difficile; Cross I | 2007 |
Use of intravenous immunoglobulin for the treatment of severe Clostridium difficile colitis.
Topics: Aged; Anti-Bacterial Agents; Carcinoma, Merkel Cell; Clostridioides difficile; Cytotoxins; Diarrhea; | 2007 |
Is it Clostridium difficile infection or something else? A case-control study of 352 hospitalized patients with new-onset diarrhea.
Topics: Aged; Analysis of Variance; Case-Control Studies; Cefazolin; Ceftriaxone; Clostridioides difficile; | 2007 |
Pseudomembranous colitis in a patient treated with ofloxacin for tuberculosis.
Topics: Aged; Antitubercular Agents; Enterocolitis, Pseudomembranous; Humans; Male; Ofloxacin; Tuberculosis, | 1996 |
[Pseudomembranous colitis caused by ofloxacin].
Topics: Enterocolitis, Pseudomembranous; Humans; Male; Ofloxacin | 1990 |
Clostridium difficile colitis associated with ofloxacin therapy.
Topics: Aged; Clostridium; Enterocolitis, Pseudomembranous; Humans; Male; Ofloxacin | 1989 |