Page last updated: 2024-11-01

ofloxacin and Anemia, Aplastic

ofloxacin has been researched along with Anemia, Aplastic in 3 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Anemia, Aplastic: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.

Research Excerpts

ExcerptRelevanceReference
"These findings suggest that, despite increasing rates of antimicrobial resistance, levofloxacin prophylaxis during neutropenia may have a beneficial impact on morbidity and infection-related mortality."5.11Impact of fluoroquinolone prophylaxis on reduced infection-related mortality among patients with neutropenia and hematologic malignancies. ( Döhner, H; Kern, P; Kern, WV; Marre, R; Reuter, S; Sigge, A; von Baum, H, 2005)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Postnikov, SS1
Semykin, SIu1
Nazhimov, VP1
Novichkova, GA1
Reuter, S1
Kern, WV1
Sigge, A1
Döhner, H1
Marre, R1
Kern, P1
von Baum, H1
Weber, C1
Maas, R1
Steiner, P1
Kramer, J1
Bumann, D1
Zander, AR1
Bücheler, E1

Trials

2 trials available for ofloxacin and Anemia, Aplastic

ArticleYear
[On fluoroquinolones treatment safety in children (clinical, morphological and catamnesis data)].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2002, Volume: 47, Issue:9

    Topics: Adolescent; Age Factors; Anemia, Aplastic; Anti-Infective Agents; Body Height; Cartilage; Child; Chi

2002
Impact of fluoroquinolone prophylaxis on reduced infection-related mortality among patients with neutropenia and hematologic malignancies.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Apr-15, Volume: 40, Issue:8

    Topics: Amyloidosis; Anemia, Aplastic; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections;

2005

Other Studies

1 other study available for ofloxacin and Anemia, Aplastic

ArticleYear
[Importance of digital thoracic radiography in the diagnosis of pulmonary infiltrates in patients with bone marrow transplantation during aplasia].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1999, Volume: 171, Issue:4

    Topics: Adult; Anemia, Aplastic; Anti-Infective Agents; Antibiotic Prophylaxis; Antifungal Agents; Bone Marr

1999