ofloxacin has been researched along with Albinism in 2 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Albinism: General term for a number of inherited defects of amino acid metabolism in which there is a deficiency or absence of pigment in the eyes, skin, or hair.
| Excerpt | Relevance | Reference |
|---|---|---|
| " g(-1) at 24 h after dosing and declined slowly with a terminal half-life of 468." | 1.32 | Absorption, distribution and excretion of 14C-levofloxacin after single oral administration in albino and pigmented rats: binding characteristics of levofloxacin-related radioactivity to melanin in vivo. ( Ono, C; Tanaka, M; Yamada, M, 2004) |
| " The pharmacokinetic parameters were determined with RSTRIP, an iterative, nonlinear, weighted, least-squares regression program." | 1.29 | Pharmacokinetics of ofloxacin in serum and vitreous humor of albino and pigmented rabbits. ( Drusano, G; Liu, W; Madu, A; Madu, C; Mayers, M; Miller, MH; Perkins, RJ, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tanaka, M | 1 |
| Ono, C | 1 |
| Yamada, M | 1 |
| Perkins, RJ | 1 |
| Liu, W | 1 |
| Drusano, G | 1 |
| Madu, A | 1 |
| Mayers, M | 1 |
| Madu, C | 1 |
| Miller, MH | 1 |
2 other studies available for ofloxacin and Albinism
| Article | Year |
|---|---|
Absorption, distribution and excretion of 14C-levofloxacin after single oral administration in albino and pigmented rats: binding characteristics of levofloxacin-related radioactivity to melanin in vivo.
Topics: Albinism; Animals; Anti-Infective Agents; Area Under Curve; Carbon Radioisotopes; Chloroquine; Levof | 2004 |
Pharmacokinetics of ofloxacin in serum and vitreous humor of albino and pigmented rabbits.
Topics: Albinism; Animals; Male; Ofloxacin; Pigmentation; Rabbits; Retinal Pigments; Vitreous Body | 1995 |