ofloxacin has been researched along with Adenoma, Prostatic in 10 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This multicenter clinical study was designed to compare FRPM 300 mg 3 times daily to Levofloxacin (LVFX), which is the standard treatment for patients with UTI, 100 mg 3 times daily for 7 days in the treatment of urinary tract infections in patients with neurogenic bladder and/or benign prostatic hypertrophy." | 9.10 | [Faropenem 300 mg 3 times daily versus levofloxacin 100 mg 3 times daily in the treatment of urinary tract infections in patients with neurogenic bladder and/or benign prostatic hypertrophy]. ( Fujimoto, N; Iihara, K; Inatomi, H; Kobayashi, T; Matsumoto, T; Muratani, T; Nishimura, T; Takahashi, K; Yamada, Y, 2002) |
| "The minimal inhibitory concentrations (MIC) of ofloxacin against 400 isolates cultured from the urine of urological patients with complicated urinary tract infections (UTI) resulted in an inhibition of 94% (99%) of the gram-negative strains at a concentration of 1 mg/l (2 mg/l) and an inhibition of 59% (100%) of the gram-positive strains at a concentration of 1 mg/l (4 mg/l)." | 7.67 | [In vitro activity, serum, urine and prostatic adenoma concentrations of ofloxacin in urologic patients with complicated urinary tract infections]. ( Adam, D; Bartosik-Wich, B; Naber, KG; Wittenberger, R, 1986) |
| " This multicenter clinical study was designed to compare FRPM 300 mg 3 times daily to Levofloxacin (LVFX), which is the standard treatment for patients with UTI, 100 mg 3 times daily for 7 days in the treatment of urinary tract infections in patients with neurogenic bladder and/or benign prostatic hypertrophy." | 5.10 | [Faropenem 300 mg 3 times daily versus levofloxacin 100 mg 3 times daily in the treatment of urinary tract infections in patients with neurogenic bladder and/or benign prostatic hypertrophy]. ( Fujimoto, N; Iihara, K; Inatomi, H; Kobayashi, T; Matsumoto, T; Muratani, T; Nishimura, T; Takahashi, K; Yamada, Y, 2002) |
| "The minimal inhibitory concentrations (MIC) of ofloxacin against 400 isolates cultured from the urine of urological patients with complicated urinary tract infections (UTI) resulted in an inhibition of 94% (99%) of the gram-negative strains at a concentration of 1 mg/l (2 mg/l) and an inhibition of 59% (100%) of the gram-positive strains at a concentration of 1 mg/l (4 mg/l)." | 3.67 | [In vitro activity, serum, urine and prostatic adenoma concentrations of ofloxacin in urologic patients with complicated urinary tract infections]. ( Adam, D; Bartosik-Wich, B; Naber, KG; Wittenberger, R, 1986) |
| "The present study was undertaken to evaluate the clinical efficacy of long-term administration of ofloxacin (OFLX) to the patients following transurethral resection of the prostate." | 2.67 | [Study of the long-term administration of ofloxacin to the patients following transurethral resection of the prostate]. ( Hasuda, A; Morita, M; Suzuki, K, 1991) |
| "Ten patients with clinical symptoms of benign prostatic hyperplasia undergoing TUR-P received 200 mg of both drugs per os simultaneously 2 hours before surgery." | 1.31 | Comparison of ofloxacin and norfloxacin concentration in prostatic tissues in patients undergoing transurethral resection of the prostate. ( Chen, J; Chen, RR; Huang, HS, 2001) |
| "Ofloxacin has the advantage against ciprofloxacin of exceeding the MICs for Staphylococcus and Chlamydia." | 1.30 | A comparative study of the distribution of ofloxacin and ciprofloxacin in prostatic tissues after simultaneous oral ingestion. ( Cheng, C; Foo, KT; Li, MK; Png, JC; Rekhraj, IR; Tan, E, 1997) |
| "Ofloxacin was administered orally at a dose of 200 mg several hours before subcapsular prostatectomy." | 1.29 | [Ofloxacin concentration in prostatic tissue]. ( Imada, N; Kamoi, K; Kawauchi, A; Kitamori, T; Ohne, T; Terasaki, T; Watanabe, H, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muratani, T | 1 |
| Iihara, K | 1 |
| Nishimura, T | 1 |
| Inatomi, H | 1 |
| Fujimoto, N | 1 |
| Kobayashi, T | 1 |
| Yamada, Y | 1 |
| Takahashi, K | 1 |
| Matsumoto, T | 1 |
| Tash, K | 1 |
| Kawauchi, A | 1 |
| Kamoi, K | 1 |
| Ohne, T | 1 |
| Imada, N | 1 |
| Kitamori, T | 1 |
| Terasaki, T | 1 |
| Watanabe, H | 1 |
| Png, JC | 1 |
| Tan, E | 1 |
| Foo, KT | 1 |
| Li, MK | 1 |
| Cheng, C | 1 |
| Rekhraj, IR | 1 |
| Chen, J | 1 |
| Chen, RR | 1 |
| Huang, HS | 1 |
| Morita, M | 2 |
| Ito, S | 1 |
| Suzuki, K | 2 |
| Uchibayashi, T | 1 |
| Nagano, K | 1 |
| Shoda, R | 1 |
| Hisazumi, H | 1 |
| Sawaki, M | 1 |
| Yamaguchi, K | 1 |
| Kawaguchi, K | 1 |
| Komatsu, K | 1 |
| Kobashi, K | 1 |
| Koizumi, H | 1 |
| Hasuda, A | 1 |
| Naber, KG | 1 |
| Adam, D | 1 |
| Wittenberger, R | 1 |
| Bartosik-Wich, B | 1 |
| Asakawa, M | 1 |
| Yasumoto, R | 1 |
2 trials available for ofloxacin and Adenoma, Prostatic
| Article | Year |
|---|---|
[Faropenem 300 mg 3 times daily versus levofloxacin 100 mg 3 times daily in the treatment of urinary tract infections in patients with neurogenic bladder and/or benign prostatic hypertrophy].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; b | 2002 |
[Study of the long-term administration of ofloxacin to the patients following transurethral resection of the prostate].
Topics: Aged; Drug Administration Schedule; Drug Evaluation; Humans; Male; Middle Aged; Ofloxacin; Postopera | 1991 |
8 other studies available for ofloxacin and Adenoma, Prostatic
| Article | Year |
|---|---|
Rahnella aquatilis bacteremia from a suspected urinary source.
Topics: Aged; Anti-Bacterial Agents; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Lev | 2005 |
[Ofloxacin concentration in prostatic tissue].
Topics: Aged; Aged, 80 and over; Humans; Male; Middle Aged; Ofloxacin; Permeability; Prostate; Prostatic Hyp | 1993 |
A comparative study of the distribution of ofloxacin and ciprofloxacin in prostatic tissues after simultaneous oral ingestion.
Topics: Administration, Oral; Anti-Infective Agents; Anti-Infective Agents, Urinary; Chromatography, High Pr | 1997 |
Comparison of ofloxacin and norfloxacin concentration in prostatic tissues in patients undergoing transurethral resection of the prostate.
Topics: Aged; Anti-Infective Agents; Humans; Male; Middle Aged; Norfloxacin; Ofloxacin; Postoperative Compli | 2001 |
[Clinical evaluation of oral ofloxacin in 3-day therapy for transurethral resection of the prostate].
Topics: Administration, Oral; Aged; Aged, 80 and over; Drug Administration Schedule; Humans; Male; Middle Ag | 1992 |
[Diffusion of ofloxacin (OFLX) into prostatic tissue in patients with benign prostatic hypertrophy].
Topics: Administration, Oral; Aged; Aged, 80 and over; Humans; Male; Middle Aged; Ofloxacin; Prostate; Prost | 1990 |
[In vitro activity, serum, urine and prostatic adenoma concentrations of ofloxacin in urologic patients with complicated urinary tract infections].
Topics: Aged; Anti-Infective Agents, Urinary; Bacteria; Cross Infection; Dose-Response Relationship, Drug; F | 1986 |
Ofloxacin concentration in human benign prostatic tissue after oral administration.
Topics: Administration, Oral; Aged; Aged, 80 and over; Humans; Male; Ofloxacin; Prostate; Prostatic Hyperpla | 1988 |