ofloxacin has been researched along with Acute Necrotizing Pancreatitis in 2 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The clinical course and death rate in acute necrotizing pancreatitis (ANP) are largely determined by septic complications as part of bacterial invasion of the necrotic tissues." | 2.68 | [Antibiotic use in necrotizing pancreatitis. Results of a controlled study]. ( Beger, HG; Isenmann, R; Meyer, H; Schwarz, M, 1997) |
| "An early stage of acute necrotizing pancreatitis did not have a major effect on the pancreatic concentrations of the antibiotics." | 1.30 | Penetration of antibiotics into the pancreas in rats: an effect of acute necrotizing pancreatitis. ( Martínek, J; Melenovsky, V; Morávek, J; Spicák, J; Závada, F, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schwarz, M | 1 |
| Isenmann, R | 1 |
| Meyer, H | 1 |
| Beger, HG | 1 |
| Spicák, J | 1 |
| Martínek, J | 1 |
| Závada, F | 1 |
| Morávek, J | 1 |
| Melenovsky, V | 1 |
1 trial available for ofloxacin and Acute Necrotizing Pancreatitis
| Article | Year |
|---|---|
[Antibiotic use in necrotizing pancreatitis. Results of a controlled study].
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacterial Infections; Biopsy, Needle; Drug Th | 1997 |
1 other study available for ofloxacin and Acute Necrotizing Pancreatitis
| Article | Year |
|---|---|
Penetration of antibiotics into the pancreas in rats: an effect of acute necrotizing pancreatitis.
Topics: Amikacin; Amoxicillin; Animals; Anti-Bacterial Agents; Cefoperazone; Clavulanic Acid; Female; Ofloxa | 1999 |