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ofloxacin and Acute Necrotizing Pancreatitis

ofloxacin has been researched along with Acute Necrotizing Pancreatitis in 2 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"The clinical course and death rate in acute necrotizing pancreatitis (ANP) are largely determined by septic complications as part of bacterial invasion of the necrotic tissues."2.68[Antibiotic use in necrotizing pancreatitis. Results of a controlled study]. ( Beger, HG; Isenmann, R; Meyer, H; Schwarz, M, 1997)
"An early stage of acute necrotizing pancreatitis did not have a major effect on the pancreatic concentrations of the antibiotics."1.30Penetration of antibiotics into the pancreas in rats: an effect of acute necrotizing pancreatitis. ( Martínek, J; Melenovsky, V; Morávek, J; Spicák, J; Závada, F, 1999)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schwarz, M1
Isenmann, R1
Meyer, H1
Beger, HG1
Spicák, J1
Martínek, J1
Závada, F1
Morávek, J1
Melenovsky, V1

Trials

1 trial available for ofloxacin and Acute Necrotizing Pancreatitis

ArticleYear
[Antibiotic use in necrotizing pancreatitis. Results of a controlled study].
    Deutsche medizinische Wochenschrift (1946), 1997, Mar-21, Volume: 122, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacterial Infections; Biopsy, Needle; Drug Th

1997

Other Studies

1 other study available for ofloxacin and Acute Necrotizing Pancreatitis

ArticleYear
Penetration of antibiotics into the pancreas in rats: an effect of acute necrotizing pancreatitis.
    Scandinavian journal of gastroenterology, 1999, Volume: 34, Issue:1

    Topics: Amikacin; Amoxicillin; Animals; Anti-Bacterial Agents; Cefoperazone; Clavulanic Acid; Female; Ofloxa

1999