ofloxacin has been researched along with Abnormalities, Drug-Induced in 2 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "(4) Grepafloxacin was the most active quinolone in this assay." | 1.31 | Ultrastructural characterization of murine limb buds after in vitro exposure to grepafloxacin and other fluoroquinolones. ( Baumann-Wilschke, I; Rücker, M; Shakibaei, M; Stahlmann, R, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shakibaei, M | 1 |
| Baumann-Wilschke, I | 1 |
| Rücker, M | 1 |
| Stahlmann, R | 1 |
| Davis, GJ | 1 |
| McKenzie, BE | 1 |
1 review available for ofloxacin and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Toxicologic evaluation of ofloxacin.
Topics: Abnormalities, Drug-Induced; Acute Disease; Animals; Chronic Disease; Dogs; Ofloxacin; Rats | 1989 |
1 other study available for ofloxacin and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Ultrastructural characterization of murine limb buds after in vitro exposure to grepafloxacin and other fluoroquinolones.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Infective Agents; Calcium; Dose-Response Relationship, Dr | 2002 |