Page last updated: 2024-11-01

octopamine and Parkinson Disease

octopamine has been researched along with Parkinson Disease in 3 studies

Octopamine: An alpha-adrenergic sympathomimetic amine, biosynthesized from tyramine in the CNS and platelets and also in invertebrate nervous systems. It is used to treat hypotension and as a cardiotonic. The natural D(-) form is more potent than the L(+) form in producing cardiovascular adrenergic responses. It is also a neurotransmitter in some invertebrates.
octopamine : A member of the class of phenylethanolamines that is phenol which is substituted at the para- position by a 2-amino-1-hydroxyethyl group. A biogenic phenylethanolamine which has been found to act as a neurotransmitter, neurohormone or neuromodulator in invertebrates.

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
D'Andrea, G1
Nordera, G1
Pizzolato, G1
Bolner, A1
Colavito, D1
Flaibani, R1
Leon, A1
Boulton, AA1
Wu, PH1
Boulton, A1
Marjerrison, L1
Majer, D1

Other Studies

3 other studies available for octopamine and Parkinson Disease

ArticleYear
Trace amine metabolism in Parkinson's disease: low circulating levels of octopamine in early disease stages.
    Neuroscience letters, 2010, Jan-29, Volume: 469, Issue:3

    Topics: Aged; Amines; Biomarkers; Disease Progression; Female; Humans; Male; Middle Aged; Norepinephrine; Oc

2010
Effect of L-DOPA on the synthesis and excretion of tyramine.
    Advances in neurology, 1974, Volume: 5

    Topics: Animals; Brain Stem; Caudate Nucleus; Cerebellum; Dopamine; Humans; Hypothalamus; Levodopa; Octopami

1974
[Excretion, metabolism and central distribution of non-catecholic primary amines].
    Vestnik Akademii meditsinskikh nauk SSSR, 1971, Volume: 26, Issue:5

    Topics: Animals; Brain; Humans; Octopamine; Parkinson Disease; Phenethylamines; Phenylacetates; Rats; Schizo

1971