octopamine has been researched along with Parkinson Disease in 3 studies
Octopamine: An alpha-adrenergic sympathomimetic amine, biosynthesized from tyramine in the CNS and platelets and also in invertebrate nervous systems. It is used to treat hypotension and as a cardiotonic. The natural D(-) form is more potent than the L(+) form in producing cardiovascular adrenergic responses. It is also a neurotransmitter in some invertebrates.
octopamine : A member of the class of phenylethanolamines that is phenol which is substituted at the para- position by a 2-amino-1-hydroxyethyl group. A biogenic phenylethanolamine which has been found to act as a neurotransmitter, neurohormone or neuromodulator in invertebrates.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (66.67) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
D'Andrea, G | 1 |
Nordera, G | 1 |
Pizzolato, G | 1 |
Bolner, A | 1 |
Colavito, D | 1 |
Flaibani, R | 1 |
Leon, A | 1 |
Boulton, AA | 1 |
Wu, PH | 1 |
Boulton, A | 1 |
Marjerrison, L | 1 |
Majer, D | 1 |
3 other studies available for octopamine and Parkinson Disease
Article | Year |
---|---|
Trace amine metabolism in Parkinson's disease: low circulating levels of octopamine in early disease stages.
Topics: Aged; Amines; Biomarkers; Disease Progression; Female; Humans; Male; Middle Aged; Norepinephrine; Oc | 2010 |
Effect of L-DOPA on the synthesis and excretion of tyramine.
Topics: Animals; Brain Stem; Caudate Nucleus; Cerebellum; Dopamine; Humans; Hypothalamus; Levodopa; Octopami | 1974 |
[Excretion, metabolism and central distribution of non-catecholic primary amines].
Topics: Animals; Brain; Humans; Octopamine; Parkinson Disease; Phenethylamines; Phenylacetates; Rats; Schizo | 1971 |