Page last updated: 2024-11-01

octopamine and Muscle Contraction

octopamine has been researched along with Muscle Contraction in 54 studies

Octopamine: An alpha-adrenergic sympathomimetic amine, biosynthesized from tyramine in the CNS and platelets and also in invertebrate nervous systems. It is used to treat hypotension and as a cardiotonic. The natural D(-) form is more potent than the L(+) form in producing cardiovascular adrenergic responses. It is also a neurotransmitter in some invertebrates.
octopamine : A member of the class of phenylethanolamines that is phenol which is substituted at the para- position by a 2-amino-1-hydroxyethyl group. A biogenic phenylethanolamine which has been found to act as a neurotransmitter, neurohormone or neuromodulator in invertebrates.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"Octopamine was identified in the spermathecal tissue of Locusta migratoria using HPLC and immunohistochemical techniques."5.32Octopamine modulates spermathecal muscle contractions in Locusta migratoria. ( Clark, J; Lange, AB, 2003)
"The biogenic amines, serotonin, octopamine, tyramine and dopamine regulate many essential processes in parasitic nematodes, such as pharyngeal pumping, muscle contraction, and egg-laying, as well as more complex behaviors, such as mechanosensation and foraging, making biogenic amine receptors excellent targets for drug discovery."4.82Biogenic amine receptors in parasitic nematodes: what can be learned from Caenorhabditis elegans? ( Hapiak, VM; Hobson, RJ; Komuniecki, PR; Komuniecki, RW; Rex, EB, 2004)
"Both octopamine and proctolin potentiate nerve-evoked skeletal muscle contractions in the horseshoe crab, Limulus."3.67Neuromuscular modulation in Limulus by both octopamine and proctolin. ( Gerlach, PH; Rane, SG; Wyse, GA, 1984)
"Octopamine was identified in the spermathecal tissue of Locusta migratoria using HPLC and immunohistochemical techniques."1.32Octopamine modulates spermathecal muscle contractions in Locusta migratoria. ( Clark, J; Lange, AB, 2003)
"3."1.28Tyramine antagonizes proctolin-induced contraction of the isolated foregut of the locust Schistocerca gregaria by an interaction with octopamine2 receptors. ( Banner, SE; Cattell, KJ; Osborne, RH; Wood, SJ, 1990)
"Octopamine can increase the strength of contraction of exoskeletal muscles and, at higher concentrations, can induce contractures in these muscles."1.26Octopamine neurons in lobsters: location, morphology, release of octopamine and possible physiological role. ( Battelle, BA; Evans, PD; Kravitz, EA; Talamo, BR; Wallace, BG, 1976)
" Systemic administration of alpha-methyldopa to rats for 15 days shifted the log dose-response curves for all three catecholamines, but not vasopressin or potassium chloride, to the right of all three blood vessel types; the maximal contractile responses to these amines were, however, not affected by chronic treatment with alpha-methyldopa."1.25Pharmacological effects of alpha-methyldopa, alpha-methylnorepinephrine, and octopamine on rat arteriolar, arterial, and terminal vascular smooth. ( Altura, BM, 1975)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199040 (74.07)18.7374
1990's4 (7.41)18.2507
2000's5 (9.26)29.6817
2010's4 (7.41)24.3611
2020's1 (1.85)2.80

Authors

AuthorsStudies
Leclerc, G1
Bizec, JC1
Bieth, N1
Schwartz, J1
de Oliveira, DMN1
Oliveira-Silva, CA1
Pinheiro, CG1
de Carvalho, EF1
Gadelha, KKL1
Lima-Silva, K1
Cavalcante, AKM1
Belém, MO1
Paula, SM1
Dos Santos, AA1
Magalhães, PJC1
Solari, P1
Rivelli, N1
De Rose, F1
Picciau, L1
Murru, L1
Stoffolano, JG1
Liscia, A1
Ormerod, KG1
Hadden, JK1
Deady, LD1
Mercier, AJ2
Krans, JL1
Tamashiro, H1
Yoshino, M1
Hana, S1
Lange, AB4
Clark, J1
Komuniecki, RW1
Hobson, RJ1
Rex, EB1
Hapiak, VM1
Komuniecki, PR1
Middleton, CA1
Nongthomba, U1
Parry, K1
Sweeney, ST1
Sparrow, JC1
Elliott, CJ1
Rodríguez-Valentín, R1
López-González, I1
Jorquera, R1
Labarca, P1
Zurita, M1
Reynaud, E1
Kobayashi, M1
Muneoka, Y3
Kravitz, EA4
Glusman, S1
Harris-Warrick, RM2
Livingstone, MS1
Schwarz, T1
Goy, MF1
Olsson, OA2
Ahlquist, B1
Gustafsson, B2
Kamura, M2
Tanaka, KR2
Webb, RA2
Matsuura, M1
Hoyle, G3
Rane, SG1
Gerlach, PH1
Wyse, GA1
Reimann, W1
Evans, PD6
Gee, JD1
Anderson, WG1
Field, LH1
Siegler, MV1
Ségalat, L1
Elkes, DA1
Kaplan, JM1
Vidal, AM1
del Castillo, J1
Smith, DS1
Mizutani, K1
Ogawa, H1
Saito, J1
Oka, K1
O'Shea, M1
Ruben, PC1
Swann, JW1
Carpenter, DO1
Battelle, BA2
Gardner, CR1
Talamo, BR1
Wallace, BG1
Altura, BM1
Cook, BJ1
Wagner, RM1
Banner, SE1
Wood, SJ1
Osborne, RH1
Cattell, KJ1
Orchard, I2
Wilkens, JL1
Fischer, L1
Florey, E1
Lafi, MA2
Leake, LD2
Celuch, SM1
Juorio, AV1
Kelly, RJ1
Burks, TF1
Fischer, JE1
Weise, VK1
Kopin, IJ1
Patil, PN1
Tye, A1
LaPidus, JB1
Enright, D1
Choi, YS1
Di Palma, JR1
Antonaccio, MJ1
Smith, CB1
Sentíes, L1
Arellano, G1
Casellas, A1
Ontiveros, E1
Santos, J1
Klepping, J1
Escousse, A1
Truchot, R1
Didier, JP1
Tron-Loisel, H1

Reviews

1 review available for octopamine and Muscle Contraction

ArticleYear
Biogenic amine receptors in parasitic nematodes: what can be learned from Caenorhabditis elegans?
    Molecular and biochemical parasitology, 2004, Volume: 137, Issue:1

    Topics: Animals; Caenorhabditis elegans; Dopamine; Locomotion; Muscle Contraction; Nematoda; Octopamine; Pha

2004

Other Studies

53 other studies available for octopamine and Muscle Contraction

ArticleYear
Synthesis and structure-activity relationships among alpha-adrenergic receptor agonists of the phenylethanolamine type.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:7

    Topics: Adrenergic alpha-Agonists; Animals; Aorta; Ethanolamines; In Vitro Techniques; Muscle Contraction; M

1980
Differential effects of β-methylphenylethylamine and octopamine on contractile parameters of the rat gastrointestinal tract.
    European journal of pharmacology, 2021, Oct-05, Volume: 908

    Topics: Amphetamines; Animals; Gastric Fundus; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Octopa

2021
Opposite effects of 5-HT/AKH and octopamine on the crop contractions in adult Drosophila melanogaster: Evidence of a double brain-gut serotonergic circuitry.
    PloS one, 2017, Volume: 12, Issue:3

    Topics: Animals; Brain; Digestive System; Drosophila melanogaster; Insect Hormones; Male; Muscle Contraction

2017
Action of octopamine and tyramine on muscles of Drosophila melanogaster larvae.
    Journal of neurophysiology, 2013, Volume: 110, Issue:8

    Topics: Animals; Drosophila melanogaster; Larva; Membrane Potentials; Muscle Contraction; Muscle, Skeletal;

2013
Signaling pathway underlying the octopaminergic modulation of myogenic contraction in the cricket lateral oviduct.
    Journal of insect physiology, 2014, Volume: 71

    Topics: Animals; Female; Gryllidae; Muscle Contraction; Neurotransmitter Agents; Octopamine; Oviducts; Signa

2014
Octopamine and tyramine regulate the activity of reproductive visceral muscles in the adult female blood-feeding bug,
    The Journal of experimental biology, 2017, 05-15, Volume: 220, Issue:Pt 10

    Topics: Animals; Cyclic AMP; Female; Muscle Contraction; Muscle, Smooth; Octopamine; Oviducts; Phentolamine;

2017
Octopamine modulates spermathecal muscle contractions in Locusta migratoria.
    Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2003, Volume: 189, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Electrophysiolog

2003
Neuromuscular organization and aminergic modulation of contractions in the Drosophila ovary.
    BMC biology, 2006, Jun-12, Volume: 4

    Topics: Animals; Drosophila; Female; Muscle Contraction; Muscles; Neuromuscular Junction; Octopamine; Ovary;

2006
Oviduct contraction in Drosophila is modulated by a neural network that is both, octopaminergic and glutamatergic.
    Journal of cellular physiology, 2006, Volume: 209, Issue:1

    Topics: Animals; Drosophila; Drosophila Proteins; Female; Ganglion Cysts; Glutamic Acid; In Vitro Techniques

2006
Modulatory actions of octopamine and serotonin on the contraction of buccal muscles in Rapana thomasiana--I. Enhancement of contraction in radula protractor.
    Comparative biochemistry and physiology. C: Comparative pharmacology, 1980, Volume: 65, Issue:2

    Topics: Acetylcholine; Animals; Biological Assay; Catecholamines; Cheek; Electric Stimulation; Glutamates; M

1980
Amines and a peptide as neurohormones in lobsters: actions on neuromuscular preparations and preliminary behavioural studies.
    The Journal of experimental biology, 1980, Volume: 89

    Topics: Action Potentials; Animals; Calcium; Dopamine; Electric Conductivity; gamma-Aminobutyric Acid; Membr

1980
A new beta 2-adrenoceptor agonist with alpha 1-adrenoceptor blocking properties.
    Acta pharmacologica et toxicologica, 1981, Volume: 48, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Aorta; Dose-Response Relationship,

1981
Actions of noradrenaline and some other biogenic amines on the body-wall muscles of an echiuroid, Urechis unicinctus.
    Comparative biochemistry and physiology. C: Comparative pharmacology, 1982, Volume: 72, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Biogenic Amines; Echinodermata; Electric Stimulation; In Vitr

1982
Octopamine action on the spontaneous contractions of the isolated nerve cord of Lumbricus terrestris.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1983, Volume: 76, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug

1983
Pharmacological evidence for the existence of presynaptic alpha-like receptors in Mytilus muscle.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1983, Volume: 76, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bivalvia; Electric Stimulation; Mu

1983
Neuromuscular transmission in a primitive insect: modulation by octopamine, and catch-like tension.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1984, Volume: 77, Issue:2

    Topics: Animals; Membrane Potentials; Muscle Contraction; Neuromuscular Junction; Octopamine; Orthoptera; Sy

1984
Neuromuscular modulation in Limulus by both octopamine and proctolin.
    Journal of neurobiology, 1984, Volume: 15, Issue:3

    Topics: Animals; Aspartic Acid; Biogenic Amines; Calcium; Drug Interactions; Evoked Potentials; Glutamates;

1984
Evidence for neuronal uptake and release of norfenefrine and evaluation of its alpha-agonistic effects in the rabbit pulmonary artery.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:5

    Topics: 2-Hydroxyphenethylamine; Adrenergic alpha-Agonists; alpha-Methyltyrosine; Animals; Calcium; Drug Int

1984
Action of formamidine pesticides on octopamine receptors.
    Nature, 1980, Sep-04, Volume: 287, Issue:5777

    Topics: Amidines; Animals; Chlorphenamidine; Dose-Response Relationship, Drug; Grasshoppers; Muscle Contract

1980
Multiple receptor types for octopamine in the locust.
    The Journal of physiology, 1981, Volume: 318

    Topics: Animals; Dose-Response Relationship, Drug; Female; Grasshoppers; In Vitro Techniques; Male; Muscle C

1981
Octopamine in Lumbricus terrestris: presence, synthesis and effect of octopamine on the spontaneous rhythmic contractions of the ventral nerve cord.
    Brain research, 1983, Jan-31, Volume: 260, Issue:1

    Topics: Animals; Dopamine; Epinephrine; Membrane Potentials; Muscle Contraction; Norepinephrine; Octopamine;

1983
The sympathomimetic activity of N-isopropyloctopamine in vitro.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:3

    Topics: Animals; Aorta; Atrial Function; Biological Assay; Cyclic AMP; Guinea Pigs; Heart Atria; Isoproteren

1983
Elicitation and abrupt termination of behaviorally significant catchlike tension in a primitive insect.
    Journal of neurobiology, 1983, Volume: 14, Issue:4

    Topics: Animals; Female; Ganglia; Male; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscles; Neurom

1983
Cellular mechanisms for modulation of posture by octopamine and serotonin in the lobster.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1984, Volume: 4, Issue:8

    Topics: Animals; Evoked Potentials; Ganglia; Motor Activity; Muscle Contraction; Nephropidae; Nervous System

1984
Octopamine mediated relaxation of maintained and catch tension in locust skeletal muscle.
    The Journal of physiology, 1982, Volume: 324

    Topics: Animals; Evoked Potentials; Female; Grasshoppers; Male; Motor Neurons; Muscle Contraction; Muscle Re

1982
Modulation of serotonin-controlled behaviors by Go in Caenorhabditis elegans.
    Science (New York, N.Y.), 1995, Mar-17, Volume: 267, Issue:5204

    Topics: Animals; Animals, Genetically Modified; Behavior, Animal; Caenorhabditis elegans; Cloning, Molecular

1995
Contractile properties of the articular capsule or ligament, in the primary spines of the sea-urchin Eucidaris tribuloides.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1993, Volume: 106, Issue:3

    Topics: Acetylcholine; Animals; In Vitro Techniques; Ligaments; Muscle Contraction; Nicotine; Octopamine; Pa

1993
Fictive locomotion induced by octopamine in the earthworm.
    The Journal of experimental biology, 2002, Volume: 205, Issue:Pt 2

    Topics: Adrenergic alpha-Agonists; Animals; Electrophysiology; Locomotion; Muscle Contraction; Octopamine; O

2002
The identification of an octopaminergic neurone and the modulation of a myogenic rhythm in the locust.
    The Journal of experimental biology, 1978, Volume: 73

    Topics: Action Potentials; Animals; Extremities; Female; Ganglia; Grasshoppers; Male; Muscle Contraction; Ne

1978
Neurotransmitter receptors on gill muscle fibers and the gill peripheral nerve plexus in Aplysia.
    Canadian journal of physiology and pharmacology, 1979, Volume: 57, Issue:10

    Topics: Animals; Aplysia; Gills; Muscle Contraction; Muscles; Neurotransmitter Agents; Octopamine; Receptors

1979
Targets of octopamine action in the lobster: cyclic nucleotide changes and physiological effects in hemolymph, heart and exoskeletal muscle.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 205, Issue:2

    Topics: Animals; Blood Coagulation; Heart Rate; Hemolymph; Muscle Contraction; Muscles; Myocardial Contracti

1978
Octopamine and synephrine evoke a different response to other monoamines on the body wall of Lumbricus terrestris.
    Neuropharmacology, 1979, Volume: 18, Issue:4

    Topics: Amphetamines; Animals; Biogenic Amines; Electric Stimulation; In Vitro Techniques; Muscle Contractio

1979
Octopamine neurons in lobsters: location, morphology, release of octopamine and possible physiological role.
    Cold Spring Harbor symposia on quantitative biology, 1976, Volume: 40

    Topics: Animals; Electric Stimulation; Evoked Potentials; Ganglia; Kinetics; Mixed Function Oxygenases; Musc

1976
Pharmacological effects of alpha-methyldopa, alpha-methylnorepinephrine, and octopamine on rat arteriolar, arterial, and terminal vascular smooth.
    Circulation research, 1975, Volume: 36, Issue:6 Suppl 1

    Topics: Administration, Topical; Animals; Aorta, Thoracic; Blood Vessels; Dopamine; Dose-Response Relationsh

1975
Evidence that insect dorsal unpaired medican (DUM) neurons are octopaminergic.
    The Journal of experimental zoology, 1975, Volume: 193, Issue:3

    Topics: Action Potentials; Animals; Grasshoppers; Male; Muscle Contraction; Neurons; Octopamine; Orthoptera

1975
Some pharmacological properties of the oviduct muscularis of the stable fly Stomoxys calcitrans.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1992, Volume: 102, Issue:2

    Topics: Animals; Female; Glutamates; Glutamic Acid; Male; Muscidae; Muscle Contraction; Muscle, Smooth; Neur

1992
Tyramine antagonizes proctolin-induced contraction of the isolated foregut of the locust Schistocerca gregaria by an interaction with octopamine2 receptors.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1990, Volume: 95, Issue:2

    Topics: Animals; Caffeine; Digestive System; Digestive System Physiological Phenomena; Dose-Response Relatio

1990
Identified octopaminergic neurons modulate contractions of locust visceral muscle via adenosine 3',5'-monophosphate (cyclic AMP).
    Brain research, 1986, Jan-22, Volume: 363, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Biogenic Amines; Colforsin; Cyclic AMP; Female; Grasshoppers;

1986
The effect of D2343 in transmurally stimulated rabbit isthmus muscle.
    Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Dose-Response Relationship, Drug; E

1985
Modulatory effects of proctolin on a crab ventilatory muscle.
    Journal of neurobiology, 1985, Volume: 16, Issue:5

    Topics: Animals; Brachyura; Dopamine; Gills; Muscle Contraction; Muscles; Neuropeptides; Neurotransmitter Ag

1985
Octopamine action on the contractile system of crustacean skeletal muscle.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1987, Volume: 88, Issue:2

    Topics: Animals; Astacoidea; Caffeine; Calcium; Glutamates; In Vitro Techniques; Muscle Contraction; Muscles

1987
Actions of dopamine and related amines on reserpinized and chronically denervated vasa deferentia of the rat.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1988, Volume: 89, Issue:2

    Topics: Amines; Animals; Denervation; Dopamine; Guanethidine; In Vitro Techniques; Male; Metoclopramide; Mus

1988
Tonic and rhythmic contractions induced by dopamine and related amines in rat vasa deferentia are pharmacologically separable.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1988, Volume: 90, Issue:1

    Topics: Amines; Animals; Calcium; Carbachol; Cocaine; Dopamine; In Vitro Techniques; Male; Methoxamine; Musc

1988
Pre- and postsynaptic effects of p-tyramine and p-octopamine in the prostatic portion of the rat vas deferens.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Male; Muscle Contraction; Muscle, Smoot

1988
Regional differences in responsiveness to octopamine within a locust skeletal muscle.
    The Journal of physiology, 1985, Volume: 366

    Topics: 2-Hydroxyphenethylamine; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Extremities; Grassho

1985
Evidence for octopaminergic modulation of an insect visceral muscle.
    Journal of neurobiology, 1985, Volume: 16, Issue:3

    Topics: Animals; Biogenic Amines; Dose-Response Relationship, Drug; Female; Grasshoppers; Muscle Contraction

1985
Relative vasoconstrictor potencies of norepinephrine, alpha-methylnorepinephrine and octopamine.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 208, Issue:2

    Topics: Acetophenones; Acetylcholine; Adrenergic alpha-Antagonists; Animals; Atropine; Blood Pressure; Cocai

1974
Release of tritiated bretylium by sympathetic nerve stimulation.
    Nature, 1966, Feb-19, Volume: 209, Issue:5025

    Topics: Animals; Bretylium Compounds; Cats; Electric Stimulation; Ethanolamines; Heart Rate; Muscle Contract

1966
"Indirect" sympathomimetic effects of L(+)-isomers and desoxy derivatives.
    The Journal of pharmacy and pharmacology, 1967, Volume: 19, Issue:3

    Topics: Animals; Catecholamines; Dopamine; Ephedrine; In Vitro Techniques; Male; Muscle Contraction; Norepin

1967
Studies on the interaction of norepinephrine with some other drugs on the aortic smooth muscle of the rabbit.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 205, Issue:1

    Topics: Acetylcholine; Animals; Aorta; Atropine; Carbamates; Dose-Response Relationship, Drug; Drug Interact

1973
Effects of chronic pretreatment with pargyline upon responses of the atrial pacemaker and of left atrial strips of guinea pigs to tyramine, mephentermine, d-amphetamine and adrenergic nerve stimulation.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 170, Issue:1

    Topics: Animals; Binding Sites; Dextroamphetamine; Electric Stimulation; Female; Guinea Pigs; Heart Atria; H

1969
Effects of some vasopressor drugs upon uterine contractility in pregnant women.
    American journal of obstetrics and gynecology, 1970, Jul-15, Volume: 107, Issue:6

    Topics: Amniotic Fluid; Anencephaly; Blood Pressure; Female; Fetal Death; Fetal Heart; Heart Rate; Humans; I

1970
[Experimental study of sympathicomimetic properties of various types of amines and their iodinated derivatives. Application of the achieved data to the study of the structure of adrenergic receptors].
    Archives des sciences physiologiques, 1971, Volume: 25, Issue:1

    Topics: Adipose Tissue; Animals; Blood Pressure; Cardiovascular System; Carotid Arteries; Catecholamines; Ca

1971