octanoic acid has been researched along with Idiopathic Parkinson Disease in 7 studies
octanoic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #1764
octanoic acid : A straight-chain saturated fatty acid that is heptane in which one of the hydrogens of a terminal methyl group has been replaced by a carboxy group. Octanoic acid is also known as caprylic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rotenone is used to generate Parkinson's disease (PD)-like symptoms in experimental animals." | 1.72 | Amelioration of rotenone-induced alterations in energy/redox system, stress response and cytoskeleton proteins by octanoic acid in zebrafish: A proteomic study. ( Alturfan, AA; Büyükkayhan, D; Cansız, D; Emekli-Alturfan, E; Sürmen, MG; Sürmen, S; Ünal, İ; Üstündağ, ÜV, 2022) |
| "Rotenone is a neurotoxin that is used to induce experimental PD model." | 1.62 | Quantitative phosphoproteomics to resolve the cellular responses to octanoic acid in rotenone exposed zebrafish. ( Alturfan, AA; Cansız, D; Emekli-Alturfan, E; Sürmen, MG; Sürmen, S; Ünal, İ; Üstündağ, ÜV, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Sürmen, MG | 2 |
| Sürmen, S | 2 |
| Cansız, D | 3 |
| Ünal, İ | 3 |
| Üstündağ, ÜV | 3 |
| Alturfan, AA | 3 |
| Emekli-Alturfan, E | 3 |
| Büyükkayhan, D | 1 |
| Altinoz, MA | 1 |
| Elmacı, İ | 1 |
| Joniec-Maciejak, I | 1 |
| Wawer, A | 1 |
| Turzyńska, D | 1 |
| Sobolewska, A | 1 |
| Maciejak, P | 1 |
| Szyndler, J | 1 |
| Mirowska-Guzel, D | 1 |
| Płaźnik, A | 1 |
| Epprecht, L | 1 |
| Schreglmann, SR | 1 |
| Goetze, O | 2 |
| Woitalla, D | 2 |
| Baumann, CR | 1 |
| Waldvogel, D | 1 |
| Müller, T | 1 |
| Erdmann, C | 1 |
| Unger, MM | 1 |
| Möller, JC | 1 |
| Mankel, K | 1 |
| Schmittinger, K | 1 |
| Eggert, KM | 1 |
| Stamelou, M | 1 |
| Stiasny-Kolster, K | 1 |
| Bohne, K | 1 |
| Bodden, M | 1 |
| Mayer, G | 1 |
| Oertel, WH | 1 |
| Tebbe, JJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Orthostatic Dysregulation and Associated Gastrointestinal Dysfunction in Parkinson's Disease - Evolution A Monocentric Study to Investigate the Development of Symptoms of Autonomic Dysregulation in Parkinson's Disease[NCT01518751] | 27 participants (Actual) | Observational | 2011-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for octanoic acid and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Unchanged gastric emptying and visceral perception in early Parkinson's disease after a high caloric test meal.
Topics: Adult; Aged; Appetite; Benserazide; Breath Tests; Caprylates; Dopamine Agents; Drug Combinations; Ga | 2015 |
Entacapone improves absorption of a coadministered salt in patients with Parkinson's disease.
Topics: Adult; Aged; Antiparkinson Agents; Breath Tests; Caprylates; Carbidopa; Carbon Isotopes; Catechol O- | 2008 |
Patients with idiopathic rapid-eye-movement sleep behavior disorder show normal gastric motility assessed by the 13C-octanoate breath test.
Topics: Adult; Aged; Breath Tests; Caprylates; Carbon Isotopes; Enteric Nervous System; Female; Gastric Empt | 2011 |
4 other studies available for octanoic acid and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Quantitative phosphoproteomics to resolve the cellular responses to octanoic acid in rotenone exposed zebrafish.
Topics: Animals; Caprylates; Parkinson Disease; Rotenone; Zebrafish | 2021 |
Amelioration of rotenone-induced alterations in energy/redox system, stress response and cytoskeleton proteins by octanoic acid in zebrafish: A proteomic study.
Topics: Animals; Caprylates; Chromatography, Liquid; Cytoskeletal Proteins; Cytoskeleton; Oxidation-Reductio | 2022 |
Caprylic acid ameliorates rotenone induced inflammation and oxidative stress in the gut-brain axis in Zebrafish.
Topics: Animals; Brain; Brain-Gut Axis; Caprylates; Disease Models, Animal; Gastrointestinal Tract; Glutathi | 2021 |
Octanoic acid prevents reduction of striatal dopamine in the MPTP mouse model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Caprylates; C | 2018 |