octanoic acid has been researched along with Hepatic Encephalopathy in 8 studies
octanoic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #1764
octanoic acid : A straight-chain saturated fatty acid that is heptane in which one of the hydrogens of a terminal methyl group has been replaced by a carboxy group. Octanoic acid is also known as caprylic acid.
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with hepatic encephalopathy and Reye's syndrome have elevated levels of plasma octanoate." | 5.28 | On octanoic acid-induced hyperventilation--implications for hepatic encephalopathy and Reye's syndrome. ( Jumbasova, S; Kostadinova, I; Krustev, A; Mitkov, D; Toreva, D, 1989) |
| "To assess neuronal mechanisms of potential importance in the pathogenesis of hepatic encephalopathy, visual evoked potentials were recorded in rabbits with acute hyperammonemic encephalopathy, postictal coma, and toxin-induced coma resulting from the administration of a combination of subcoma doses of three neurotoxins: ammonia, dimethyldisulfide, and octanoic acid." | 3.67 | Visual evoked potentials in a rabbit model of hepatic encephalopathy. II. Comparison of hyperammonemic encephalopathy, postictal coma, and coma induced by synergistic neurotoxins. ( Ferenci, P; Jones, EA; Pappas, SC; Schafer, DF, 1984) |
| "Patients with hepatic encephalopathy and Reye's syndrome have elevated levels of plasma octanoate." | 1.28 | On octanoic acid-induced hyperventilation--implications for hepatic encephalopathy and Reye's syndrome. ( Jumbasova, S; Kostadinova, I; Krustev, A; Mitkov, D; Toreva, D, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baraldi, M | 1 |
| Pinelli, G | 1 |
| Ricci, P | 1 |
| Zeneroli, ML | 1 |
| Pappas, SC | 1 |
| Ferenci, P | 1 |
| Schafer, DF | 1 |
| Jones, EA | 2 |
| Mitkov, D | 3 |
| Murphy, MG | 1 |
| Crocker, JF | 1 |
| Her, H | 1 |
| Zieve, L | 1 |
| Dozeman, R | 1 |
| Kristev, A | 1 |
| Lukanov, Y | 1 |
| Chapkynov, P | 1 |
| Toreva, D | 1 |
| Krustev, A | 1 |
| Kostadinova, I | 1 |
| Jumbasova, S | 1 |
| Jones, DB | 1 |
| Mullen, KD | 1 |
| Roessle, M | 1 |
| Maynard, T | 1 |
8 other studies available for octanoic acid and Hepatic Encephalopathy
| Article | Year |
|---|---|
Toxins in hepatic encephalopathy: the role of the synergistic effect of ammonia, mercaptans and short chain fatty acids.
Topics: Ammonia; Animals; Caprylates; Drug Synergism; Hepatic Encephalopathy; Kinetics; Rats; Receptors, GAB | 1984 |
Visual evoked potentials in a rabbit model of hepatic encephalopathy. II. Comparison of hyperammonemic encephalopathy, postictal coma, and coma induced by synergistic neurotoxins.
Topics: Ammonia; Animals; Caprylates; Disease Models, Animal; Disulfides; Evoked Potentials, Visual; Galacto | 1984 |
The role of the octanoic fatty acid in the pathogenesis of the metabolic alkalosis in experimental liver failure.
Topics: Alkalosis; Animals; Bicarbonates; Caprylates; Hepatic Encephalopathy; Liver Failure; Muscle Proteins | 1993 |
Abnormalities in hepatic fatty-acid metabolism in a surfactant/influenza B virus mouse model for acute encephalopathy.
Topics: Adenosine Triphosphate; Administration, Cutaneous; Animals; Caprylates; Disease Models, Animal; Emul | 1996 |
Effect of hepatic failure toxins on regenerative enzymes in the liver after injury with galactosamine in the rat.
Topics: Acetaminophen; Ammonium Chloride; Animals; Caprylates; Chemical and Drug Induced Liver Injury; Disul | 1989 |
The effect of octanoic fatty acid on the cardiovascular system of the guinea pig.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Caprylates; Cardiac Output; Cardiovascular Disease | 1989 |
On octanoic acid-induced hyperventilation--implications for hepatic encephalopathy and Reye's syndrome.
Topics: Alkalosis, Respiratory; Animals; Blood Pressure; Caprylates; Electroencephalography; Hepatic Encepha | 1989 |
Hepatic encephalopathy. Application of visual evoked responses to test hypotheses of its pathogenesis in rats.
Topics: Ammonia; Animals; Caprylates; Disulfides; Evoked Potentials, Visual; gamma-Aminobutyric Acid; Hepati | 1987 |