Page last updated: 2024-10-17

octanoic acid and Graves Disease

octanoic acid has been researched along with Graves Disease in 1 studies

octanoic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #1764
octanoic acid : A straight-chain saturated fatty acid that is heptane in which one of the hydrogens of a terminal methyl group has been replaced by a carboxy group. Octanoic acid is also known as caprylic acid.

Graves Disease: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).

Research Excerpts

ExcerptRelevanceReference
"Graves' disease is attributed to the presence of autoantibodies with agonist activity which interact with the TSH receptor causing thyroid hyperstimulation and hyperthyroidism."1.29The antibodies causing thyroid stimulating hormone-binding inhibition (TSH-BI) are not responsible for the specific inhibition of gonadal steroidogenesis by Graves' sera. ( Castel, MA; Hunt, N; Leidenberger, F; Willey, KP, 1996)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Castel, MA1
Willey, KP1
Hunt, N1
Leidenberger, F1

Other Studies

1 other study available for octanoic acid and Graves Disease

ArticleYear
The antibodies causing thyroid stimulating hormone-binding inhibition (TSH-BI) are not responsible for the specific inhibition of gonadal steroidogenesis by Graves' sera.
    Journal of reproductive immunology, 1996, Volume: 30, Issue:1

    Topics: Ammonium Sulfate; Autoantibodies; Caprylates; Graves Disease; HeLa Cells; Humans; Immunoglobulin G;

1996