Page last updated: 2024-10-17

octanoic acid and Gastroparesis

octanoic acid has been researched along with Gastroparesis in 11 studies

octanoic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #1764
octanoic acid : A straight-chain saturated fatty acid that is heptane in which one of the hydrogens of a terminal methyl group has been replaced by a carboxy group. Octanoic acid is also known as caprylic acid.

Gastroparesis: Chronic delayed gastric emptying. Gastroparesis may be caused by motor dysfunction or paralysis of STOMACH muscles or may be associated with other systemic diseases such as DIABETES MELLITUS.

Research Excerpts

ExcerptRelevanceReference
"In this double-blind cross-over study, we assessed whether erythromycin infusion is effective as a prokinetic drug against gastroparesis from acute pain."9.12Erythromycin promotes gastric emptying during acute pain in volunteers. ( Allaouchiche, B; Bleyzac, N; Boselli, E; Bouvet, L; Chassard, D; Duflo, F; Mion, F, 2006)
"In this double-blind cross-over study, we assessed whether erythromycin infusion is effective as a prokinetic drug against gastroparesis from acute pain."5.12Erythromycin promotes gastric emptying during acute pain in volunteers. ( Allaouchiche, B; Bleyzac, N; Boselli, E; Bouvet, L; Chassard, D; Duflo, F; Mion, F, 2006)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (27.27)18.2507
2000's4 (36.36)29.6817
2010's4 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nguyen, NQ1
Bryant, LK1
Burgstad, CM1
Chapman, M1
Deane, A1
Bellon, M1
Lange, K1
Bartholomeuz, D1
Horowitz, M1
Holloway, RH1
Fraser, RJ1
Bruno, G1
Lopetuso, LR1
Ianiro, G1
Laterza, L1
Gerardi, V1
Petito, V1
Poscia, A1
Gasbarrini, A1
Ojetti, V1
Scaldaferri, F1
Gourcerol, G1
Tissier, F1
Melchior, C1
Touchais, JY1
Huet, E1
Prevost, G1
Leroi, AM1
Ducrotte, P1
Braden, B1
Caspary, W1
Börner, N1
Vinson, B1
Schneider, AR1
Perri, F1
Bellini, M1
Portincasa, P1
Parodi, A1
Bonazzi, P1
Marzio, L1
Galeazzi, F1
Usai, P1
Citrino, A1
Usai-Satta, P1
Zahn, A1
Langhans, CD1
Hoffner, S1
Haberkorn, U1
Rating, D1
Haass, M1
Enck, P1
Stremmel, W1
Rühl, A1
Bouvet, L1
Duflo, F1
Bleyzac, N1
Mion, F1
Boselli, E1
Allaouchiche, B1
Chassard, D1
Pfaffenbach, B1
Wegener, M1
Adamek, RJ1
Wissuwa, H1
Schaffstein, J1
Aygen, S1
Hennemann, O1
Schadewaldt, P2
Schommartz, B2
Wienrich, G1
Brösicke, H1
Piolot, R1
Ziegler, D2
Lee, JS1
Camilleri, M1
Zinsmeister, AR1
Burton, DD1
Choi, MG1
Nair, KS1
Verlinden, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Use of Endoscopic Functional Lumen Imaging Probe (EndoFLIP) and Antroduodenal Manometry (ADM) in Predicting Clinical Response to Gastric Peroral Endoscopic Myotomy (G-POEM): A Pilot Study[NCT04844190]20 participants (Anticipated)Interventional2021-09-15Recruiting
Effect of a 5-day Adaptation and Deadaptation Periods to a High-fat Diet Supplemented With Specific Fatty Acids on Gastrointestinal Transit, Appetite and Substrate Utilisation[NCT01510223]24 participants (Actual)Interventional2010-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for octanoic acid and Gastroparesis

ArticleYear
13C-octanoic acid breath test to study gastric emptying time.
    European review for medical and pharmacological sciences, 2013, Volume: 17 Suppl 2

    Topics: Biomarkers; Breath Tests; Caprylates; Carbon Dioxide; Carbon Isotopes; Gases; Gastric Emptying; Gast

2013

Trials

3 trials available for octanoic acid and Gastroparesis

ArticleYear
Clinical effects of STW 5 (Iberogast) are not based on acceleration of gastric emptying in patients with functional dyspepsia and gastroparesis.
    Neurogastroenterology and motility, 2009, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Breath Tests; Caprylates; Double-Blind Method; Dyspepsia

2009
Measurement of gastric emptying by 13C-octanoic acid breath test versus scintigraphy in diabetics.
    Zeitschrift fur Gastroenterologie, 2003, Volume: 41, Issue:5

    Topics: Adult; Aged; Autonomic Nervous System; Autonomic Nervous System Diseases; Breath Tests; Caprylates;

2003
Erythromycin promotes gastric emptying during acute pain in volunteers.
    Anesthesia and analgesia, 2006, Volume: 102, Issue:6

    Topics: Acetaminophen; Acute Disease; Adult; Breath Tests; Caprylates; Cold Temperature; Cross-Over Studies;

2006

Other Studies

7 other studies available for octanoic acid and Gastroparesis

ArticleYear
Gastric emptying measurement of liquid nutrients using the (13)C-octanoate breath test in critically ill patients: a comparison with scintigraphy.
    Intensive care medicine, 2013, Volume: 39, Issue:7

    Topics: Breath Tests; Caprylates; Carbon Isotopes; Critical Illness; Enteral Nutrition; Female; Gastric Empt

2013
Impaired fasting pyloric compliance in gastroparesis and the therapeutic response to pyloric dilatation.
    Alimentary pharmacology & therapeutics, 2015, Volume: 41, Issue:4

    Topics: Adult; Breath Tests; Caprylates; Dilatation; Esophagectomy; Fasting; Female; Gastric Emptying; Gastr

2015
(13)C-octanoic acid breath test (OBT) with a new test meal (EXPIROGer): Toward standardization for testing gastric emptying of solids.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2010, Volume: 42, Issue:8

    Topics: Adult; Breath Tests; Caprylates; Carbon Isotopes; Celiac Disease; Diabetic Neuropathies; Diagnostic

2010
[Non-invasive 13C octanoic acid breath test for measuring stomach emptying of a solid test meal--correlation with scintigraphy in diabetic patients and reproducibility in healthy probands].
    Zeitschrift fur Gastroenterologie, 1995, Volume: 33, Issue:3

    Topics: Aged; Aged, 80 and over; Caprylates; Carbon Radioisotopes; Diabetes Mellitus; Diabetic Neuropathies;

1995
Application of isotope-selective nondispersive infrared spectrometry (IRIS) for evaluation of [13C]octanoic acid gastric-emptying breath tests: comparison with isotope ratio-mass spectrometry (IRMS).
    Clinical chemistry, 1997, Volume: 43, Issue:3

    Topics: Adult; Antihypertensive Agents; Breath Tests; Caprylates; Carbon Dioxide; Carbon Isotopes; Diabetes

1997
Significance of diagnostic parameters in [13C]octanoic acid gastric emptying breath tests.
    Isotopes in environmental and health studies, 1998, Volume: 34, Issue:1-2

    Topics: Adult; Breath Tests; Caprylates; Carbon Dioxide; Carbon Isotopes; Case-Control Studies; Diabetes Mel

1998
Toward office-based measurement of gastric emptying in symptomatic diabetics using [13C]octanoic acid breath test.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:10

    Topics: Adult; Aged; Ambulatory Care; Breath Tests; Caprylates; Carbon Radioisotopes; Diabetes Mellitus, Typ

2000