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octanoic acid and Envenomation, Snakebite

octanoic acid has been researched along with Envenomation, Snakebite in 6 studies

octanoic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #1764
octanoic acid : A straight-chain saturated fatty acid that is heptane in which one of the hydrogens of a terminal methyl group has been replaced by a carboxy group. Octanoic acid is also known as caprylic acid.

Research Excerpts

ExcerptRelevanceReference
"51) in the incidence of early adverse reactions to antivenom administration (28."2.77Comparative study of the efficacy and safety of two polyvalent, caprylic acid fractionated [IgG and F(ab')2] antivenoms, in Bothrops asper bites in Colombia. ( Angulo, Y; Arrieta, AB; Arroyo, Y; Barona, J; Betancur, D; Conrado, NL; Córdoba, EA; Díaz, A; Estrada, S; Fabra, P; Fernández, D; Fernández, J; Gómez, JP; Gutiérrez, JM; Herrera, M; León, G; Mosquera, DC; Ortiz, R; Otero-Patiño, R; Perea, M; Pereañez, A; Pupo, L; Quintana, JC; Ramírez, CE; Ramírez, P; Rivero, A; Segura, A; Suárez, AM; Vargas, LJ, 2012)
" The incidence of early adverse reactions (all mild) was similar for both antivenoms (15% and 24%; P>0."2.72Efficacy and safety of two whole IgG polyvalent antivenoms, refined by caprylic acid fractionation with or without beta-propiolactone, in the treatment of Bothrops asper bites in Colombia. ( Alzate, C; Arrieta, AB; Arroyo, Y; Ayala, S; Barona, J; Conrado, LL; Córdoba, E; Díaz, A; Fabra, PE; Fernández, D; Fernández, J; Gutiérrez, JM; León, G; López, M; Meza, JJ; Mosquera, D; Núñez, V; Ospina, CE; Otero, R; Paniagua, CA; Quintana, JC; Ramírez, E; Ramírez, P; Rodríguez, V; Rojas, G; Silva, JF; Theakston, RD; Toro, MF; Warrell, DA, 2006)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Zurbano, BN1
Tavarone, E1
Viacava, BG1
Dokmetjian, JC1
Cascone, O1
Fingermann, M1
Vargas, M1
Segura, A2
Herrera, M2
Villalta, M1
Estrada, R1
Cerdas, M1
Paiva, O1
Matainaho, T1
Jensen, SD1
Winkel, KD1
León, G5
Gutiérrez, JM5
Williams, DJ1
Otero-Patiño, R1
Angulo, Y1
Barona, J2
Estrada, S1
Pereañez, A1
Quintana, JC2
Vargas, LJ1
Gómez, JP1
Díaz, A3
Suárez, AM1
Fernández, J2
Ramírez, P2
Fabra, P1
Perea, M1
Fernández, D2
Arroyo, Y2
Betancur, D1
Pupo, L1
Córdoba, EA1
Ramírez, CE1
Arrieta, AB2
Rivero, A1
Mosquera, DC1
Conrado, NL1
Ortiz, R1
García, M2
Monge, M1
Lizano, S2
Segura, E1
Solano, G1
Rojas, G3
Otero, R2
Toro, MF2
Rodríguez, V1
Núñez, V2
Ayala, S1
Mosquera, D1
Conrado, LL1
Paniagua, CA1
López, M1
Ospina, CE1
Alzate, C1
Meza, JJ1
Silva, JF2
Fabra, PE1
Ramírez, E1
Córdoba, E1
Warrell, DA1
Theakston, RD1
Miranda, E1
Uribe, AF1
Ospina, JG1
Medina, Y1
García, ME1
De La Torre, J1
Márquez, J1
Mena, Y1
González, N1
Arenas, LC1
Puzón, A1
Blanco, N1
Sierra, A1
Espinal, ME1
Lozano, R1

Trials

3 trials available for octanoic acid and Envenomation, Snakebite

ArticleYear
Comparative study of the efficacy and safety of two polyvalent, caprylic acid fractionated [IgG and F(ab')2] antivenoms, in Bothrops asper bites in Colombia.
    Toxicon : official journal of the International Society on Toxinology, 2012, Volume: 59, Issue:2

    Topics: Adolescent; Animals; Antivenins; Blood Coagulation; Blood Coagulation Disorders; Bothrops; Caprylate

2012
Efficacy and safety of two whole IgG polyvalent antivenoms, refined by caprylic acid fractionation with or without beta-propiolactone, in the treatment of Bothrops asper bites in Colombia.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2006, Volume: 100, Issue:12

    Topics: Adolescent; Adult; Aged; Animals; Antivenins; Blood Coagulation Disorders; Bothrops; Caprylates; Che

2006
A randomized blinded clinical trial of two antivenoms, prepared by caprylic acid or ammonium sulphate fractionation of IgG, in Bothrops and Porthidium snake bites in Colombia: correlation between safety and biochemical characteristics of antivenoms.
    Toxicon : official journal of the International Society on Toxinology, 1999, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Aged; Ammonium Sulfate; Animals; Antivenins; Bothrops; Caprylates; Chemical Fract

1999

Other Studies

3 other studies available for octanoic acid and Envenomation, Snakebite

ArticleYear
Critical aspects on traditional antivenom production processes and their optimization by factorial analysis.
    Biologicals : journal of the International Association of Biological Standardization, 2020, Volume: 68

    Topics: Ammonium Sulfate; Animals; Antivenins; Blood Proteins; Caprylates; Chromatography, Gel; Chromatograp

2020
Preclinical evaluation of caprylic acid-fractionated IgG antivenom for the treatment of Taipan (Oxyuranus scutellatus) envenoming in Papua New Guinea.
    PLoS neglected tropical diseases, 2011, Volume: 5, Issue:5

    Topics: Animals; Antivenins; Caprylates; Chemical Fractionation; Elapidae; Female; Horses; Immunoglobulin G;

2011
Effect of preservatives on IgG aggregation, complement-activating effect and hypotensive activity of horse polyvalent antivenom used in snakebite envenomation.
    Biologicals : journal of the International Association of Biological Standardization, 2002, Volume: 30, Issue:2

    Topics: Animals; Antihypertensive Agents; Antivenins; Caprylates; Chromatography, Gel; Complement Activation

2002