octanoic acid has been researched along with Brain Edema in 2 studies
octanoic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #1764
octanoic acid : A straight-chain saturated fatty acid that is heptane in which one of the hydrogens of a terminal methyl group has been replaced by a carboxy group. Octanoic acid is also known as caprylic acid.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Brain edema is a leading cause of death in fulminant hepatic failure (FHP)." | 2.38 | Brain edema in acute liver failure. Insight from experimental studies. ( Andres, T; Blei, MD; Cho, MD; Judy, R, 1990) |
| "Octanoic acid has been implicated in the pathogenesis of cytotoxic cerebral edema in Reye's syndrome." | 1.28 | Octanoic acid inhibits astrocyte volume control: implications for cerebral edema in Reye's syndrome. ( Holtzman, D; Lawson, C; Olson, JE; Rosenberg, R; Sankar, R, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andres, T | 1 |
| Blei, MD | 1 |
| Judy, R | 1 |
| Cho, MD | 1 |
| Olson, JE | 1 |
| Holtzman, D | 1 |
| Sankar, R | 1 |
| Lawson, C | 1 |
| Rosenberg, R | 1 |
1 review available for octanoic acid and Brain Edema
| Article | Year |
|---|---|
Brain edema in acute liver failure. Insight from experimental studies.
Topics: Animals; Brain Edema; Caprylates; Disease Models, Animal; Dogs; Galactosamine; Hepatectomy; Hepatic | 1990 |
1 other study available for octanoic acid and Brain Edema
| Article | Year |
|---|---|
Octanoic acid inhibits astrocyte volume control: implications for cerebral edema in Reye's syndrome.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Brain Edema; Ca(2+) Mg(2+)-ATPase; Caprylates; Cells, C | 1989 |