Page last updated: 2024-08-18

obidoxime chloride and Disease Models, Animal

obidoxime chloride has been researched along with Disease Models, Animal in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Barry, J; Bohnert, S; Cochrane, L; Cornelissen, AS; Joosen, MJA; Kentrop, J; Klaassen, SD; Savransky, V; van Groningen, T1
Appu, AP; Arun, P; Braga, MF; Figueiredo, TH; Flagg, T; Krishnan, JKS; Moffett, JR; Namboodiri, AM; Puthillathu, N1
Bird, M; Green, AC; Kassa, J; Tattersall, JEH; Timperley, CM; Williams, RL1
Cohen, Y; Eisenkraft, A; Kadar, T; Kassirer, M; Milk, N; Rosman, Y; Shiyovich, A; Shrot, S; Tauber, M1
Bajgar, J; Karasova, J; Kassa, J; Kuca, K; Musilek, K; Vasina, L1
Humlicek, V; Kassa, J1
Benesová, O; Hvizdosová, J1

Other Studies

7 other study(ies) available for obidoxime chloride and Disease Models, Animal

ArticleYear
Pharmacokinetics and efficacy of atropine sulfate/obidoxime chloride co-formulation against VX in a guinea pig model.
    Regulatory toxicology and pharmacology : RTP, 2021, Volume: 119

    Topics: Acetylcholinesterase; Animals; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Drug Combinations; Guinea Pigs; Male; Muscarinic Antagonists; Obidoxime Chloride; Organothiophosphorus Compounds; Treatment Outcome

2021
Brief isoflurane administration as a post-exposure treatment for organophosphate poisoning.
    Neurotoxicology, 2017, Volume: 63

    Topics: Amygdala; Anesthetics, Inhalation; Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Follow-Up Studies; Hippocampus; Isoflurane; Male; Obidoxime Chloride; Organophosphate Poisoning; Paraoxon; Rats; Rats, Sprague-Dawley; Time Factors

2017
Some benefit from non-oximes MB408, MB442 and MB444 in combination with the oximes HI-6 or obidoxime and atropine in antidoting sarin or cyclosarin poisoned mice.
    Toxicology, 2018, 09-01, Volume: 408

    Topics: Animals; Atropine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Lethal Dose 50; Male; Mice; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Sarin; Time Factors

2018
Early brain magnetic resonance imaging can predict short and long-term outcomes after organophosphate poisoning in a rat model.
    Neurotoxicology, 2015, Volume: 48

    Topics: Animals; Aspartic Acid; Atropine; Behavior, Animal; Brain; Brain Edema; Choline; Cholinesterase Reactivators; Cognition; Creatine; Disease Models, Animal; Drug Therapy, Combination; Early Diagnosis; Magnetic Resonance Imaging; Male; Maze Learning; Midazolam; Neuroprotective Agents; Obidoxime Chloride; Organophosphate Poisoning; Paraoxon; Predictive Value of Tests; Proton Magnetic Resonance Spectroscopy; Rats, Sprague-Dawley; Scopolamine; Time Factors; Weight Loss

2015
A comparison of neuroprotective efficacy of newly developed oximes (K203, K206) and commonly used oximes (obidoxime, HI-6) in tabun-poisoned rats.
    Drug and chemical toxicology, 2009, Volume: 32, Issue:2

    Topics: Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Male; Neuroprotective Agents; Neurotoxicity Syndromes; Obidoxime Chloride; Organophosphates; Organophosphorus Compounds; Oximes; Rats; Rats, Wistar

2009
A comparison of the potency of newly developed oximes (K074, K075) and currently available oximes (obidoxime, trimedoxime, HI-6) to counteract acute toxic effects of tabun and cyclosarin in mice.
    Drug and chemical toxicology, 2008, Volume: 31, Issue:1

    Topics: Animals; Antidotes; Atropine; Butanes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Lethal Dose 50; Male; Mice; Muscarinic Antagonists; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Oximes; Poisoning; Pyridinium Compounds; Trimedoxime

2008
[Traumatic shock and cholinesterase reactivators].
    Casopis lekaru ceskych, 1973, Volume: 112, Issue:6

    Topics: Animals; Cholinesterase Reactivators; Cholinesterases; Disease Models, Animal; Enzyme Activation; Male; Obidoxime Chloride; Oximes; Pyridinium Compounds; Rats; Shock, Traumatic

1973