obeticholic-acid has been researched along with Hepatitis--Autoimmune* in 3 studies
2 review(s) available for obeticholic-acid and Hepatitis--Autoimmune
| Article | Year |
|---|---|
[Research advances in autoimmune liver diseases in 2016].
Autoimmune liver diseases are a group of abnormal autoimmune-mediated inflammatory hepatobiliary injuries, mainly including autoimmune hepatitis(AIH), primary biliary cholangitis(PBC), and primary sclerosing cholangitis (PSC). The diagnosis and treatment of autoimmune liver diseases, an important type of non-viral liver disease, have become a prominent issue in hepatology. In 2016, many new advances have been achieved in the clinical and basic research on autoimmune liver diseases, including the phase 3 clinical trial of obeticholic acid, the proposal of UK-PBC risk score, and the research on gut microbiota associated with PSC. This article reviews the research advances in the diagnosis and treatment of autoimmune liver diseases in 2016.. 自身免疫性肝病是一组由异常自身免疫介导的肝胆炎症性损伤，主要包括自身免疫性肝炎、原发性胆汁性胆管炎及原发性硬化性胆管炎等。作为非病毒性肝病的重要成员，自身免疫性肝病的诊断与治疗日益成为肝病领域的突出问题之一。2016年，自身免疫性肝病在临床和基础研究方面又有了许多新进展，包括奥贝胆酸的临床III期试验，UK-PBC危险评分的提出，以及原发性硬化性胆管炎相关的肠道微生态研究等。现就自身免疫性肝病2016年的诊疗与研究进展进行介绍。. Topics: Autoimmune Diseases; Biomedical Research; Chenodeoxycholic Acid; Cholangitis; Cholangitis, Sclerosing; Clinical Trials, Phase III as Topic; Hepatitis, Autoimmune; Humans; Liver Cirrhosis, Biliary; Liver Diseases | 2017 |
FXR Agonists: From Bench to Bedside, a Guide for Clinicians.
Topics: Animals; Azepines; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholestasis; Drug Evaluation, Preclinical; Gastrointestinal Agents; Hepatitis, Autoimmune; Humans; Hypertension, Portal; Indoles; Isoxazoles; Liver Cirrhosis, Alcoholic; Liver Cirrhosis, Biliary; Liver Diseases; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid | 2016 |
1 other study(ies) available for obeticholic-acid and Hepatitis--Autoimmune
| Article | Year |
|---|---|
Effective treatment of autoimmune hepatitis-primary biliary cholangitis overlap syndrome with obeticholic acid.
There is no consensus treatment for patients with autoimmune hepatitis (AIH) - primary biliary cholangitis (PBC) overlap syndrome who are not responding to conventional therapy. We present a case of a 43-yr-old woman with AIH-PBC overlap syndrome treated with obeticholic acid (OCA). The patient showed a reduction in liver enzymes and no fibrosis progression during 15 months of follow up. Topics: Adult; Chenodeoxycholic Acid; Female; Hepatitis, Autoimmune; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid | 2020 |