o-phthalaldehyde has been researched along with Huntington Disease in 2 studies
o-Phthalaldehyde: A reagent that forms fluorescent conjugation products with primary amines. It is used for the detection of many biogenic amines, peptides, and proteins in nanogram quantities in body fluids.
phthalaldehyde : A dialdehyde in which two formyl groups are attached to adjacent carbon centres on a benzene ring.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (50.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Jeitner, TM | 1 |
Bogdanov, MB | 1 |
Matson, WR | 1 |
Daikhin, Y | 1 |
Yudkoff, M | 1 |
Folk, JE | 1 |
Steinman, L | 1 |
Browne, SE | 1 |
Beal, MF | 1 |
Blass, JP | 1 |
Cooper, AJ | 1 |
Pearson, SJ | 1 |
Czudek, C | 1 |
Mercer, K | 1 |
Reynolds, GP | 1 |
2 other studies available for o-phthalaldehyde and Huntington Disease
Article | Year |
---|---|
N(epsilon)-(gamma-L-glutamyl)-L-lysine (GGEL) is increased in cerebrospinal fluid of patients with Huntington's disease.
Topics: Adult; Chromatography, Liquid; Dipeptides; Electrochemistry; Female; Humans; Huntington Disease; Mal | 2001 |
Electrochemical detection of human brain transmitter amino acids by high-performance liquid chromatography of stable o-phthalaldehyde-sulphite derivatives.
Topics: Amino Acids; Brain Chemistry; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Huntin | 1991 |