Page last updated: 2024-11-02

o-phthalaldehyde and Huntington Disease

o-phthalaldehyde has been researched along with Huntington Disease in 2 studies

o-Phthalaldehyde: A reagent that forms fluorescent conjugation products with primary amines. It is used for the detection of many biogenic amines, peptides, and proteins in nanogram quantities in body fluids.
phthalaldehyde : A dialdehyde in which two formyl groups are attached to adjacent carbon centres on a benzene ring.

Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jeitner, TM1
Bogdanov, MB1
Matson, WR1
Daikhin, Y1
Yudkoff, M1
Folk, JE1
Steinman, L1
Browne, SE1
Beal, MF1
Blass, JP1
Cooper, AJ1
Pearson, SJ1
Czudek, C1
Mercer, K1
Reynolds, GP1

Other Studies

2 other studies available for o-phthalaldehyde and Huntington Disease

ArticleYear
N(epsilon)-(gamma-L-glutamyl)-L-lysine (GGEL) is increased in cerebrospinal fluid of patients with Huntington's disease.
    Journal of neurochemistry, 2001, Volume: 79, Issue:5

    Topics: Adult; Chromatography, Liquid; Dipeptides; Electrochemistry; Female; Humans; Huntington Disease; Mal

2001
Electrochemical detection of human brain transmitter amino acids by high-performance liquid chromatography of stable o-phthalaldehyde-sulphite derivatives.
    Journal of neural transmission. General section, 1991, Volume: 86, Issue:2

    Topics: Amino Acids; Brain Chemistry; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Huntin

1991