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o-phthalaldehyde and Colorectal Cancer

o-phthalaldehyde has been researched along with Colorectal Cancer in 2 studies

o-Phthalaldehyde: A reagent that forms fluorescent conjugation products with primary amines. It is used for the detection of many biogenic amines, peptides, and proteins in nanogram quantities in body fluids.
phthalaldehyde : A dialdehyde in which two formyl groups are attached to adjacent carbon centres on a benzene ring.

Research Excerpts

ExcerptRelevanceReference
" Blood samples were collected from 20 patients, who had received continuous intravenous infusion (CIV) of 5-FU (320 mg/m2/24 hr) after resection of colorectal cancer, and the FBAL level was determined by high performance liquid chromatography (HPLC), after derivatizing into o-phthalaldehyde (OPA) and detecting fluorescence."3.73Plasma level of a 5-fluorouracil metabolite, fluoro-beta-alanine correlates with dihydropyrimidine dehydrogenase activity of peripheral blood mononuclear cells in 5-fluorouracil treated patients. ( Furuhata, T; Hata, F; Hirata, K; Katsuramaki, T; Kawakami, M; Kihara, C; Kimura, Y; Ohmura, T; Okita, K; Sasaki, K; Tsuruma, T; Yamaguchi, K, 2006)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Furuhata, T1
Kawakami, M1
Okita, K1
Kimura, Y1
Kihara, C1
Tsuruma, T1
Ohmura, T1
Yamaguchi, K1
Hata, F1
Katsuramaki, T1
Sasaki, K1
Hirata, K1
Atatreh, N1
Barraclough, J1
Welman, A1
Cawthorne, C1
Bryce, RA1
Dive, C1
Freeman, S1

Other Studies

2 other studies available for o-phthalaldehyde and Colorectal Cancer

ArticleYear
Plasma level of a 5-fluorouracil metabolite, fluoro-beta-alanine correlates with dihydropyrimidine dehydrogenase activity of peripheral blood mononuclear cells in 5-fluorouracil treated patients.
    Journal of experimental & clinical cancer research : CR, 2006, Volume: 25, Issue:1

    Topics: Aged; Alanine; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Combined Modality Therapy

2006
Difluoro analogue of UCS15A triggers activation of exogenously expressed c-Src in HCT 116 human colorectal carcinoma cells.
    Journal of enzyme inhibition and medicinal chemistry, 2007, Volume: 22, Issue:5

    Topics: Benzaldehydes; Carcinoma; Cell Line, Tumor; Colorectal Neoplasms; Computer Simulation; Enzyme Activa

2007