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o,o-diethyl o-3,5,6-trichloro-2-pyridyl phosphate and Encephalopathy, Toxic

o,o-diethyl o-3,5,6-trichloro-2-pyridyl phosphate has been researched along with Encephalopathy, Toxic in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's4 (50.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Aschner, M; Colle, D; da Rocha, JBT; Dafré, AL; Farina, M; Leal, RB; Lopes, MW; Naime, AA; Suñol, C1
Lockridge, O; Schopfer, LM1
Liu, J; Pope, C1
Grigoryan, H; Lockridge, O1
Duysen, EG; Hansen, H; Jiang, W; Lockridge, O; Schopfer, LM; Shlyakhtenko, L1
Flaskos, J1
Costa, LG; Honegger, P; Monnet-Tschudi, F; Schilter, B; Zurich, MG1
Darvesh, S; Duysen, EG; Li, B; Lockridge, O1

Reviews

1 review(s) available for o,o-diethyl o-3,5,6-trichloro-2-pyridyl phosphate and Encephalopathy, Toxic

ArticleYear
The developmental neurotoxicity of organophosphorus insecticides: a direct role for the oxon metabolites.
    Toxicology letters, 2012, Feb-25, Volume: 209, Issue:1

    Topics: Animals; Brain; Chlorpyrifos; Cholinesterase Inhibitors; Female; Humans; Insecticides; Neurotoxicity Syndromes; Organophosphorus Compounds; Pregnancy

2012

Other Studies

7 other study(ies) available for o,o-diethyl o-3,5,6-trichloro-2-pyridyl phosphate and Encephalopathy, Toxic

ArticleYear
Glutathione in Chlorpyrifos-and Chlorpyrifos-Oxon-Induced Toxicity: a Comparative Study Focused on Non-cholinergic Toxicity in HT22 Cells.
    Neurotoxicity research, 2020, Volume: 38, Issue:3

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Cell Survival; Chlorpyrifos; Cholinesterase Inhibitors; Glutathione; Neurons; Neurotoxicity Syndromes

2020
Chlorpyrifos oxon promotes tubulin aggregation via isopeptide cross-linking between diethoxyphospho-Lys and Glu or Asp: Implications for neurotoxicity.
    The Journal of biological chemistry, 2018, 08-31, Volume: 293, Issue:35

    Topics: Acetylcholinesterase; Amino Acid Sequence; Animals; Aspartic Acid; Chlorpyrifos; Cholinesterase Inhibitors; Cross-Linking Reagents; Crystallography, X-Ray; Glutamic Acid; Lysine; Models, Molecular; Neurotoxicity Syndromes; Peptides; Phosphorylation; Protein Aggregates; Swine; Tubulin; Tyrosine

2018
The cannabinoid receptor antagonist AM251 increases paraoxon and chlorpyrifos oxon toxicity in rats.
    Neurotoxicology, 2015, Volume: 46

    Topics: Amidohydrolases; Analysis of Variance; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Chlorpyrifos; Cholinesterase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Endocannabinoids; Insecticides; Male; Monoacylglycerol Lipases; Neurotoxicity Syndromes; Paraoxon; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Time Factors; Tritium

2015
Nanoimages show disruption of tubulin polymerization by chlorpyrifos oxon: implications for neurotoxicity.
    Toxicology and applied pharmacology, 2009, Oct-15, Volume: 240, Issue:2

    Topics: Animals; Cattle; Chlorpyrifos; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Guanosine Triphosphate; Microscopy, Atomic Force; Nanostructures; Neurotoxicity Syndromes; Protein Multimerization; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Tubulin; Tubulin Modulators; Tyrosine

2009
Mice treated with chlorpyrifos or chlorpyrifos oxon have organophosphorylated tubulin in the brain and disrupted microtubule structures, suggesting a role for tubulin in neurotoxicity associated with exposure to organophosphorus agents.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 115, Issue:1

    Topics: Animals; Biotinylation; Body Temperature; Body Weight; Brain; Brain Chemistry; Chlorpyrifos; Cholinesterases; Female; Insecticides; Mass Spectrometry; Mice; Mice, Inbred Strains; Microtubule-Associated Proteins; Microtubules; Neurotoxicity Syndromes; Organophosphates; Peptide Mapping; Spectrometry, Mass, Electrospray Ionization; Tubulin; Tubulin Modulators

2010
Involvement of glial cells in the neurotoxicity of parathion and chlorpyrifos.
    Toxicology and applied pharmacology, 2004, Dec-01, Volume: 201, Issue:2

    Topics: Acetylcholinesterase; Animals; Astrocytes; Brain; Cells, Cultured; Chlorpyrifos; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Glutamate Decarboxylase; Glutamate-Ammonia Ligase; Immunohistochemistry; Insecticides; L-Lactate Dehydrogenase; Neuroglia; Neurotoxicity Syndromes; Paraoxon; Parathion; Protein Binding; Rats

2004
Sensitivity of butyrylcholinesterase knockout mice to (--)-huperzine A and donepezil suggests humans with butyrylcholinesterase deficiency may not tolerate these Alzheimer's disease drugs and indicates butyrylcholinesterase function in neurotransmission.
    Toxicology, 2007, Apr-20, Volume: 233, Issue:1-3

    Topics: Acetylcholine; Acetylcholinesterase; Alkaloids; Alzheimer Disease; Animals; Butyrylcholinesterase; Chlorpyrifos; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Dose-Response Relationship, Drug; Female; Humans; Indans; Male; Mice; Mice, Knockout; Neurotoxicity Syndromes; Piperidines; Sesquiterpenes; Synaptic Transmission

2007