o-methyl-threonine and Malaria

o-methyl-threonine has been researched along with Malaria* in 1 studies

Other Studies

1 other study(ies) available for o-methyl-threonine and Malaria

Article	Year
Dipeptides of O-methyl-L-threonine as potential antimalarials. Journal of medicinal chemistry, 1979, Volume: 22, Issue:7 L-Leucyl-O-methyl-L-threonine, O-methyl-L-threonyl-L-leucine, and O-methyl-L-threonyl-O-methyl-L-threonine were prepared and compared with O-methyl-L-threonine and L-leucine for antimalarial activity against Plasmodium berghei in mice. O-Methyl-L-threonine significantly prolonged survival time at doses of 160, 320, and 640 mg/kg. O-Methyl-L-threonyl-O-methyl-L-threonine was less active, significantly prolonging survival time only at 640 mg/kg. L-Leucine, as well as the other two dipeptides, exhibited no activity in this test. Topics: Animals; Antimalarials; Dipeptides; Malaria; Mice; Plasmodium berghei; Threonine	1979

Article

Year

Dipeptides of O-methyl-L-threonine as potential antimalarials.

Journal of medicinal chemistry, 1979, Volume: 22, Issue:7

L-Leucyl-O-methyl-L-threonine, O-methyl-L-threonyl-L-leucine, and O-methyl-L-threonyl-O-methyl-L-threonine were prepared and compared with O-methyl-L-threonine and L-leucine for antimalarial activity against Plasmodium berghei in mice. O-Methyl-L-threonine significantly prolonged survival time at doses of 160, 320, and 640 mg/kg. O-Methyl-L-threonyl-O-methyl-L-threonine was less active, significantly prolonging survival time only at 640 mg/kg. L-Leucine, as well as the other two dipeptides, exhibited no activity in this test.

Topics: Animals; Antimalarials; Dipeptides; Malaria; Mice; Plasmodium berghei; Threonine

1979