o-(6)-methylguanine has been researched along with Colonic Neoplasms in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (32.00) | 18.7374 |
| 1990's | 7 (28.00) | 18.2507 |
| 2000's | 6 (24.00) | 29.6817 |
| 2010's | 4 (16.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gold, B; Whetstone, RD | 1 |
| Decloedt, AI; Geboes, KP; Hemeryck, LY; Vanden Bussche, J; Vanhaecke, L | 1 |
| Beppu, H; Chihara, T; Higashiguchi, T; Kaneko, T; Mizutani, K; Shimpo, K; Sonoda, S | 1 |
| Kuhnle, GG; Moore, SA; Pasmans, F; Vanden Bussche, J; Vanhaecke, L | 1 |
| Chatterjee, M; Rajkumar, M; Rana, A; Rana, B; Samanta, S; Suresh, D; Swamy, V | 1 |
| Autrup, H; James, JT | 1 |
| Bull, AW; Burd, AD; Nigro, ND | 1 |
| Bignami, M; Karran, P | 1 |
| Arai, M; Ishikawa, T; Nakatsuru, Y; Oda, H; Qin, X; Zarkovic, M | 1 |
| Gerson, SL; Liu, L; Markowitz, S | 1 |
| Arimochi, H; Kataoka, K; Kinouchi, T; Kuwahara, T; Ohnishi, Y | 1 |
| Aquilina, G; Bignami, M; Crompton, NE; Jiricny, J; Lettieri, T; Marra, G; Palombo, F | 1 |
| Cooper, DP; Jackson, PE; Margison, GP; Meyer, TA; Povey, AC; Wood, M | 1 |
| Carroll, RJ; Chapkin, RS; Davidson, LA; Elder, RH; Hong, MY; Lupton, JR; Morris, JS; Wang, N | 1 |
| Moschel, RC; Pauly, GT | 1 |
| Seifert, W; Strobel, H; Vasquez, H | 1 |
| Arimochi, H; Intiyot, Y; Kataoka, K; Kinouchi, T; Kuwahara, T; Ohnishi, Y; Vinitketkumnuen, U | 1 |
| Day, RS | 1 |
| Arce, C; Berger, NA; Gerson, SL; Petzold, SJ; Willson, JK | 1 |
| Dolan, ME; Morimoto, K; Pegg, AE | 1 |
| Dolan, ME; English, HF; Larkin, GL; Pegg, AE | 1 |
| Pratviel, G; Sartorelli, AC; Shyam, K | 1 |
| Fiala, ES; Hamilton, SR; Sohn, OS | 1 |
| Tisdale, MJ | 1 |
| Gibson, NW; Hartley, J; La France, RJ; Vaughan, K | 1 |
1 review(s) available for o-(6)-methylguanine and Colonic Neoplasms
| Article | Year |
|---|---|
DNA damage tolerance, mismatch repair and genome instability.
Topics: Animals; Bacterial Proteins; Base Sequence; CHO Cells; Colonic Neoplasms; Cricetinae; DNA Damage; DNA Repair; DNA, Satellite; Escherichia coli; Female; Fungal Proteins; Genome; Guanine; Humans; Male; Mammals; Methylation; Methyltransferases; Molecular Sequence Data; Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Saccharomyces cerevisiae; Sister Chromatid Exchange | 1994 |
24 other study(ies) available for o-(6)-methylguanine and Colonic Neoplasms
| Article | Year |
|---|---|
T-cells enhance stem cell mutagenesis in the mouse colon.
Topics: Animals; Azoxymethane; Colon; Colonic Neoplasms; Dextran Sulfate; DNA Damage; Drug Synergism; Guanine; Inflammation; Male; Mice, Inbred C57BL; Mice, Knockout; Mutagenesis; Receptors, Antigen, T-Cell, alpha-beta; Stem Cells; T-Lymphocytes | 2015 |
High resolution mass spectrometry based profiling of diet-related deoxyribonucleic acid adducts.
Topics: Aged; Aged, 80 and over; Animals; Cattle; Chromatography, High Pressure Liquid; Colonic Neoplasms; Databases, Chemical; Diet; DNA; DNA Adducts; Female; Guanine; Humans; Male; Middle Aged; Tandem Mass Spectrometry | 2015 |
Inhibition of 1, 2-dimethylhydrazine-induced mucin-depleted foci and O⁶-methylguanine DNA adducts in the rat colorectum by boiled garlic powder.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Colon; Colonic Neoplasms; DNA Adducts; Garlic; Guanine; Male; Mucins; Precancerous Conditions; Rats; Rats, Inbred F344; Reactive Oxygen Species; Rectum | 2010 |
An approach based on ultra-high pressure liquid chromatography-tandem mass spectrometry to quantify O6-methyl and O6-carboxymethylguanine DNA adducts in intestinal cell lines.
Topics: Animals; Caco-2 Cells; Chromatography, High Pressure Liquid; Colonic Neoplasms; DNA; DNA Adducts; Guanine; HT29 Cells; Humans; Nitroso Compounds; Reproducibility of Results; Tandem Mass Spectrometry | 2012 |
Protective effects of vanadium against DMH-induced genotoxicity and carcinogenesis in rat colon: removal of O(6)-methylguanine DNA adducts, p53 expression, inducible nitric oxide synthase downregulation and apoptotic induction.
Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; Colon; Colonic Neoplasms; DNA Adducts; Down-Regulation; Fluorescent Antibody Technique; Guanine; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53; Vanadium | 2008 |
Methylated DNA adducts in the large intestine of ICR/Ha and C57BL/Ha mice given 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Disease Susceptibility; DNA; Guanine; Intestine, Large; Methylation; Methylhydrazines; Mice; Precancerous Conditions; Species Specificity; Time Factors | 1983 |
Effect of inhibitors of tumorigenesis on the formation of O6-methylguanine in the colon of 1,2-dimethylhydrazine-treated rats.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Dimethylhydrazines; DNA; Guanine; Male; Methylhydrazines; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1981 |
DNA adduct formation and assessment of aberrant crypt foci in vivo in the rat colon mucosa after treatment with N-methyl-N-nitrosourea.
Topics: Animals; Colon; Colonic Neoplasms; DNA; Dose-Response Relationship, Drug; Guanine; Intestinal Mucosa; Male; Methylnitrosourea; Rats; Rats, Inbred F344; Time Factors; Tritium | 1994 |
Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea.
Topics: Antineoplastic Agents, Alkylating; Carmustine; Colonic Neoplasms; Dacarbazine; DNA Adducts; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; Enzyme Inhibitors; Guanine; Humans; Methylation; Methyltransferases; Microsatellite Repeats; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Temozolomide; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1996 |
Effect of intestinal bacteria on formation of azoxymethane-induced aberrant crypt foci in the rat colon.
Topics: Animals; Azoxymethane; Bacteroides fragilis; Bifidobacterium; Body Weight; Clostridium perfringens; Colonic Neoplasms; Culture Media; Drinking; Escherichia coli; Guanine; Injections, Subcutaneous; Intestinal Mucosa; Lactobacillus acidophilus; Male; Rats; Rats, Sprague-Dawley | 1997 |
Effect of hMSH6 cDNA expression on the phenotype of mismatch repair-deficient colon cancer cell line HCT15.
Topics: Base Pair Mismatch; Base Sequence; Colonic Neoplasms; DNA Primers; DNA Repair; DNA-Binding Proteins; DNA, Complementary; G2 Phase; Guanine; Humans; Methylnitronitrosoguanidine; Methylnitrosourea; Microsatellite Repeats; Mutation; Phenotype; Transfection; Tumor Cells, Cultured | 1999 |
Formation and persistence of O(6)-methylguanine in the mouse colon following treatment with 1,2-dimethylhydrazine as measured by an O(6)-alkylguanine-DNA alkyltransferase inactivation assay.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colon; Colonic Neoplasms; DNA; DNA Methylation; Female; Guanine; Mice; O(6)-Methylguanine-DNA Methyltransferase; Reproducibility of Results | 2000 |
Dietary fish oil reduces O6-methylguanine DNA adduct levels in rat colon in part by increasing apoptosis during tumor initiation.
Topics: Analysis of Variance; Animals; Anticarcinogenic Agents; Apoptosis; Colonic Neoplasms; DNA Adducts; DNA Damage; DNA Repair; Fish Oils; Guanine; Intestinal Mucosa; Likelihood Functions; Male; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; tRNA Methyltransferases | 2000 |
Mutagenesis by O(6)-methyl-, O(6)-ethyl-, and O(6)-benzylguanine and O(4)-methylthymine in human cells: effects of O(6)-alkylguanine-DNA alkyltransferase and mismatch repair.
Topics: Base Pair Mismatch; Colonic Neoplasms; Escherichia coli; Genetic Vectors; Guanine; Humans; Kidney; Lac Operon; Mutagenesis; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; Thymine; Transfection | 2001 |
High-performance liquid chromatographic method with electrochemical detection for the analysis of O6-methylguanine.
Topics: Antineoplastic Agents; Calibration; Chromatography, High Pressure Liquid; Colonic Neoplasms; DNA Damage; Electrochemistry; Guanine; Humans; Sensitivity and Specificity; Tumor Cells, Cultured | 2001 |
Antimutagenicity of Murdannia loriformis in the Salmonella mutation assay and its inhibitory effects on azoxymethane-induced DNA methylation and aberrant crypt focus formation in male F344 rats.
Topics: Animals; Antimutagenic Agents; Antineoplastic Agents; Azoxymethane; Colon; Colonic Neoplasms; DNA Methylation; Guanine; Intestinal Mucosa; Magnoliopsida; Male; Mutagenicity Tests; Mutagens; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred F344; Salmonella typhimurium | 2002 |
Incision at O6-methylguanine:thymine mispairs in DNA by extracts of human cells.
Topics: Base Composition; Base Sequence; Binding, Competitive; Colonic Neoplasms; Deoxyribonuclease I; DNA; DNA Repair; Glioma; Guanine; Humans; Kinetics; Methylnitronitrosoguanidine; Methyltransferases; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Thymine; Tumor Cells, Cultured | 1992 |
Modulation of nitrosourea resistance in human colon cancer by O6-methylguanine.
Topics: Carmustine; Colonic Neoplasms; DNA Repair; Drug Resistance; Guanine; Humans; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured | 1992 |
Investigation of the specificity of O6-alkylguanine-DNA-alkyltransferase.
Topics: Chromatography, High Pressure Liquid; Colonic Neoplasms; DNA; DNA Repair; Escherichia coli; Guanine; Humans; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; RNA; RNA, Transfer; Substrate Specificity; Tumor Cells, Cultured | 1988 |
Depletion of O6-alkylguanine-DNA alkyltransferase activity in mammalian tissues and human tumor xenografts in nude mice by treatment with O6-methylguanine.
Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Line; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Female; Guanine; Humans; Lomustine; Mesylates; Methyltransferases; Mice; Mice, Nude; Neoplasm Transplantation; O(6)-Methylguanine-DNA Methyltransferase; Time Factors; Transplantation, Heterologous | 1989 |
Cytotoxic and DNA-damaging effects of 1,2-bis(sulfonyl)hydrazines on human cells of the Mer+ and Mer- phenotype.
Topics: Alkylating Agents; Alkylation; Colonic Neoplasms; DNA Damage; DNA Repair; DNA, Neoplasm; Guanine; Humans; Hydrazines; Methylation; Methyltransferases; Neoplasm Proteins; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Sulfones; Tumor Cells, Cultured | 1989 |
Inhibition by dietary ethanol of experimental colonic carcinogenesis induced by high-dose azoxymethane in F344 rats.
Topics: Alkylation; Animals; Azo Compounds; Azoxymethane; Colonic Neoplasms; Diet; DNA; Ethanol; Guanine; Male; Rats; Rats, Inbred F344 | 1988 |
Antitumor imidazotetrazines--XV. Role of guanine O6 alkylation in the mechanism of cytotoxicity of imidazotetrazinones.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Chlorambucil; Colonic Neoplasms; Dacarbazine; DNA Repair; Dose-Response Relationship, Drug; Guanine; Humans; Imidazoles; Kinetics; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Methyltransferases; Mice; Nitrogen Mustard Compounds; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Temozolomide | 1987 |
Differential cytotoxicity and DNA-damaging effects produced in human cells of the Mer+ and Mer- phenotypes by a series of alkyltriazenylimidazoles.
Topics: Alkylation; Antineoplastic Agents; Cell Line; Colonic Neoplasms; DNA; DNA Repair; Guanine; Humans; Triazenes | 1986 |