o-(6)-methylguanine has been researched along with Brain Neoplasms in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 7 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chamallamudi, MR; Kumar, G; Kumar, N; Nandakumar, K; Rao, V; Thorat, ND; Vibhavari, RJA | 1 |
| Cao, D; Huang, W; Su, Y; Xing, Z; Yang, X; Zhou, X | 1 |
| Baek, JY; Beom, SH; Cha, Y; Choi, J; Choi, MK; Hong, YS; Kim, J; Kim, JE; Kim, JH; Kim, SY; Kim, TW; Lee, JS; Lim, SB; Oh, CR; Park, IJ; Park, JH | 1 |
| Gupta, N; Jena, B; Kalra, M; Mohapatra, B; Saba, L; Saxena, S; Scartozzi, M; Suri, JS | 1 |
| Badalamenti, G; Barretta, ML; Buonaiuto, M; Cannella, L; Chiariotti, L; Clemente, O; De Chiara, AR; Della Monica, R; Di Marzo, M; Di Mauro, A; Guida, M; Iervolino, D; Marretta, AL; Tafuto, S; Vincenzi, B | 1 |
| Fang, X; Feng, M; Jiang, CM; Jiang, LY; Li, XL; Lin, XY; Wang, GH; Xu, JJ; Zhang, HX | 1 |
| Boldorini, R; Carriero, A; Cavalieri, S; Cossandi, C; Krengli, M; Masini, L; Stecco, A | 1 |
| Ahluwalia, MS; Angelov, L; Barnett, GH; Bellamkonda, S; Jia, X; Meola, A; Mohammadi, A; Mohapatra, S; Sharma, M; Vogelbaum, M | 1 |
| Fung, CF; Ho, AS; Kiang, KM; Lam, KF; Leung, GK; Lui, WM; Pu, JK; Sun, S; Wong, TS; Zhang, XQ | 1 |
| Barnholtz-Sloan, J; Cohen, ML; Ondracek, A; Ostrom, Q; Sloan, A | 1 |
| Blumenthal, DT; Moore, DF; Padula, GD; Rankin, C; Rushing, EJ; Schulman, SB; Sloan, AE; Spence, AM; Stelzer, KJ; Wade, ML | 1 |
| Arita, H; Fukushima, S; Ichimura, K; Matsushita, Y; Miyakita, Y; Narita, Y; Ohno, M; Shibui, S; Takami, H; Yonezawa, M; Yoshida, A | 1 |
| Luedtke, NW; Marsoner, T; Schmidt, OP; Triemer, T | 1 |
| Batista, LF; Kaina, B; Menck, CF; Naumann, SC; Roos, WP; Weller, M; Wick, W | 1 |
| Izumi, I; Kowada, M; Mineura, K; Watanabe, K | 1 |
| Ikenaga, M; Izumi, I; Kohda, K; Kowada, M; Mineura, K; Watanabe, K | 1 |
| Ikenaga, M; Izumi, I; Kohda, K; Kowada, M; Koyama, K; Mineura, K; Terashima, I; Watanabe, K | 1 |
| Chen, ZP; Garcia, Y; Langleben, A; Malapetsa, A; Mohr, G; Panasci, LC; Tampieri, D; Yarosh, D | 1 |
| Fushimi, S; Ikenaga, M; Ishizaki, K; Isowa, G; Kowada, M; Mineura, K | 1 |
| Fushimi, S; Ishino, Y; Kowada, M; Mineura, K; Sasajima, H; Sasaki, J | 1 |
| Day, RS; Scudiero, DA; Yagi, T; Yarosh, DB | 1 |
2 review(s) available for o-(6)-methylguanine and Brain Neoplasms
| Article | Year |
|---|---|
Temozolomide Resistance: A Multifarious Review on Mechanisms Beyond
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA; Glioblastoma; Humans; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide | 2023 |
Gene markers in brain tumors: what the epileptologist should know.
Topics: Biomarkers; Brain Neoplasms; CpG Islands; DNA Methylation; Epilepsy; Guanine; Humans; Mutation; Tumor Suppressor Proteins | 2013 |
2 trial(s) available for o-(6)-methylguanine and Brain Neoplasms
| Article | Year |
|---|---|
Preoperative Chemoradiotherapy With Capecitabine With or Without Temozolomide in Patients With Locally Advanced Rectal Cancer: A Prospective, Randomised Phase II Study Stratified by O
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Capecitabine; Chemoradiotherapy; Dacarbazine; DNA; DNA Methylation; DNA Repair Enzymes; Glioblastoma; Humans; Prospective Studies; Rectal Neoplasms; Temozolomide | 2023 |
A Phase III study of radiation therapy (RT) and O⁶-benzylguanine + BCNU versus RT and BCNU alone and methylation status in newly diagnosed glioblastoma and gliosarcoma: Southwest Oncology Group (SWOG) study S0001.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined Modality Therapy; DNA Methylation; Female; Glioblastoma; Gliosarcoma; Guanine; Humans; Male; Middle Aged; Radiotherapy; Young Adult | 2015 |
17 other study(ies) available for o-(6)-methylguanine and Brain Neoplasms
| Article | Year |
|---|---|
Non-invasive prediction of p53 and Ki-67 labelling indices and O-6-methylguanine-DNA methyltransferase promoter methylation status in adult patients with isocitrate dehydrogenase wild-type glioblastomas using diffusion-weighted imaging and dynamic suscept
Topics: Adult; Brain Neoplasms; DNA; Glioblastoma; Guanine; Humans; Isocitrate Dehydrogenase; Ki-67 Antigen; Magnetic Resonance Imaging; Methylation; O(6)-Methylguanine-DNA Methyltransferase; Perfusion; Retrospective Studies; Tumor Suppressor Protein p53 | 2022 |
Fused deep learning paradigm for the prediction of o6-methylguanine-DNA methyltransferase genotype in glioblastoma patients: A neuro-oncological investigation.
Topics: Biomarkers; Brain Neoplasms; Deep Learning; DNA; DNA Methylation; DNA Modification Methylases; Glioblastoma; Humans; Magnetic Resonance Imaging; Methyltransferases | 2023 |
The Impact of O6-Methylguanine-DNA Methyltransferase (
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Humans; Leiomyosarcoma; Methyltransferases; Middle Aged; Retrospective Studies; Temozolomide; Tumor Suppressor Proteins | 2023 |
CREB-induced LINC00473 promotes chemoresistance to TMZ in glioblastoma by regulating O6-methylguanine-DNA-methyltransferase expression via CEBPα binding.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA; DNA Modification Methylases; Drug Resistance, Neoplasm; Glioblastoma; Humans; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide | 2024 |
O-6-methylguanine-DNA methyltransferase (MGMT)-methylated pineal glioblastoma in young women.
Topics: Brain Neoplasms; DNA; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Guanine; Humans; O(6)-Methylguanine-DNA Methyltransferase; Tumor Suppressor Proteins | 2022 |
Correlation Between the Residual Tumor Volume, Extent of Tumor Resection, and O
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Disease-Free Survival; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Guanine; Humans; Male; Methyltransferases; Middle Aged; Neoplasm, Residual | 2018 |
A long non-coding RNA signature in glioblastoma multiforme predicts survival.
Topics: Age Factors; Brain Neoplasms; DNA Methylation; Female; Gene Expression Profiling; Glioblastoma; Guanine; Humans; Kaplan-Meier Estimate; Male; Microarray Analysis; Predictive Value of Tests; Proportional Hazards Models; RNA, Long Noncoding; Time Factors | 2013 |
Glioblastomas with IDH1/2 mutations have a short clinical history and have a favorable clinical outcome.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Chromosome Deletion; Chromosomes, Human, Pair 1; Dacarbazine; DNA Methylation; Female; Glioblastoma; Guanine; Humans; Isocitrate Dehydrogenase; Japan; Kaplan-Meier Estimate; Karnofsky Performance Status; Male; Middle Aged; Mutation; Predictive Value of Tests; Prognosis; Promoter Regions, Genetic; Temozolomide | 2016 |
DNA-Targeted Inhibition of MGMT.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; DNA; DNA Modification Methylases; DNA Repair Enzymes; Glioma; Guanine; Humans; Temozolomide; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2017 |
Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Caspases; Cell Cycle; Cell Proliferation; Dacarbazine; DNA Breaks, Double-Stranded; DNA Damage; Fas Ligand Protein; Fas-Associated Death Domain Protein; Flow Cytometry; Glioma; Guanine; Humans; Methylnitronitrosoguanidine; O(6)-Methylguanine-DNA Methyltransferase; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Temozolomide; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tumor Suppressor Protein p53 | 2007 |
Enhancement of ACNU cytotoxicity by pretreatment with O6-methylguanine in ACNU-resistant brain tumors.
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Cell Division; Densitometry; Drug Resistance; Drug Synergism; Guanine; Humans; Male; Neoplasm Transplantation; Nimustine; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured | 1994 |
Potential of O6-methylguanine or O6-benzylguanine in the enhancement of chloroethylnitrosourea cytotoxicity on brain tumours.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Basal Ganglia; Brain Neoplasms; Cell Count; Cell Division; Culture Techniques; DNA Repair; DNA, Neoplasm; Drug Synergism; Glioma; Guanine; Male; Nimustine; Rats; Rats, Wistar | 1994 |
Enhancing effect of O6-alkylguanine derivatives on chloroethylnitrosourea cytotoxicity toward tumor cells.
Topics: Animals; Brain Neoplasms; Cell Survival; Drug Synergism; Guanine; HeLa Cells; Humans; Nimustine; Rats; Structure-Activity Relationship; Tumor Cells, Cultured | 1994 |
Relationship between O6-methylguanine-DNA methyltransferase levels and clinical response induced by chloroethylnitrosourea therapy in glioma patients.
Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Brain Neoplasms; DNA Modification Methylases; Drug Resistance, Neoplasm; Female; Glioma; Guanine; Humans; Male; Middle Aged; Nitroso Compounds; Tumor Cells, Cultured | 1999 |
Linkage between O6-methylguanine-DNA methyltransferase (O6-MT) activity and cellular resistance to antitumour nitrosoureas in cultured rat brain tumour cell strains.
Topics: Animals; Brain Neoplasms; Cell Line; Guanine; Humans; Methyltransferases; Nimustine; Nitrosourea Compounds; Rats | 1990 |
[Circumvention of ACNU-resistance in rat glioma cells by pretreatment with O6-methylguanine].
Topics: Animals; Brain Neoplasms; Cell Survival; Drug Resistance; Drug Synergism; Enzyme Induction; Glioma; Guanine; Methyltransferases; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Rats; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1989 |
Human tumor cell strains both unable to repair O6-methylguanine and hypersensitive to killing by human alpha and beta interferons.
Topics: Brain Neoplasms; Cell Line; Cell Survival; DNA Repair; Guanine; Humans; In Vitro Techniques; Interferon Type I | 1985 |