o(6)-benzylguanine has been researched along with Necrosis in 1 studies
O(6)-benzylguanine: a suicide inhibitor of O(6)-methylguanine-DNA methyltransferase activity
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " With local delivery of O6BG, the MTD of BCNU in combination with O6BG was increased." | 1.31 | Toxicity of intracranial and intraperitoneal O6-benzyl guanine in combination with BCNU delivered locally in a mouse model. ( Biser-Rohrbaugh, A; Bunton, TE; Carson, BS; Gabikian, P; Guarnieri, M; Tyler, BM; Weingart, J; Wu, QZ, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guarnieri, M | 1 |
| Biser-Rohrbaugh, A | 1 |
| Tyler, BM | 1 |
| Gabikian, P | 1 |
| Bunton, TE | 1 |
| Wu, QZ | 1 |
| Weingart, J | 1 |
| Carson, BS | 1 |
1 other study available for o(6)-benzylguanine and Necrosis
| Article | Year |
|---|---|
Toxicity of intracranial and intraperitoneal O6-benzyl guanine in combination with BCNU delivered locally in a mouse model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Carmustine; Dose-Resp | 2002 |