o(6)-benzylguanine has been researched along with Colorectal Neoplasms, Hereditary Nonpolyposis in 1 studies
O(6)-benzylguanine: a suicide inhibitor of O(6)-methylguanine-DNA methyltransferase activity
Colorectal Neoplasms, Hereditary Nonpolyposis: A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bouvet, D | 1 |
| Bodo, S | 1 |
| Munier, A | 1 |
| Guillerm, E | 1 |
| Bertrand, R | 1 |
| Colas, C | 1 |
| Duval, A | 1 |
| Coulet, F | 1 |
| Muleris, M | 1 |
1 other study available for o(6)-benzylguanine and Colorectal Neoplasms, Hereditary Nonpolyposis
| Article | Year |
|---|---|
Methylation Tolerance-Based Functional Assay to Assess Variants of Unknown Significance in the MLH1 and MSH2 Genes and Identify Patients With Lynch Syndrome.
Topics: Biological Assay; Cell Line, Tumor; Colorectal Neoplasms, Hereditary Nonpolyposis; Computer Simulati | 2019 |