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o(6)-benzylguanine and Cell Transformation, Neoplastic

o(6)-benzylguanine has been researched along with Cell Transformation, Neoplastic in 3 studies

O(6)-benzylguanine: a suicide inhibitor of O(6)-methylguanine-DNA methyltransferase activity

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bishop, RE1
Dunn, LL1
Pauly, GT1
Dolan, ME1
Moschel, RC1
Boley, SE1
McManus, TP1
Maher, VM1
McCormick, JJ1
Hamdan, MA1
Guzman, RC1
Yang, J1
Beattie, C1
Mascharack, P1
Nandi, S1

Other Studies

3 other studies available for o(6)-benzylguanine and Cell Transformation, Neoplastic

ArticleYear
The role of O6-alkylguanine-DNA alkyltransferase in protecting Rat4 cells against the mutagenic effects of O6-substituted guanine residues incorporated in codon 12 of the H-ras gene.
    Carcinogenesis, 1993, Volume: 14, Issue:4

    Topics: Base Sequence; Cell Transformation, Neoplastic; Cells, Cultured; Codon; DNA Damage; DNA Repair; Gene

1993
Malignant transformation of human fibroblast cell strain MSU-1.1 by N-methyl-N-nitrosourea: evidence of elimination of p53 by homologous recombination.
    Cancer research, 2000, Aug-01, Volume: 60, Issue:15

    Topics: Alleles; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Codon; Dose-Response Relationship,

2000
Depletion of O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine in three-dimensional collagen cultures of normal human breast epithelial cells.
    Carcinogenesis, 1992, Volume: 13, Issue:10

    Topics: Animals; Base Sequence; Breast; Cell Transformation, Neoplastic; Cells, Cultured; Collagen; Culture

1992