o(6)-benzylguanine has been researched along with Carcinoma in 2 studies
O(6)-benzylguanine: a suicide inhibitor of O(6)-methylguanine-DNA methyltransferase activity
Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human pancreatic cancer L3." | 1.35 | Blockade of MGMT expression by O6 benzyl guanine leads to inhibition of pancreatic cancer growth and induction of apoptosis. ( Baker, CH; Bhakat, KK; Bobustuc, GC; Colon, J; Isley, B; Kalkunte, SS; Konduri, SD; Srivenugopal, KS; Sutphin, RM; Ticku, J, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Konduri, SD | 1 |
| Ticku, J | 1 |
| Bobustuc, GC | 1 |
| Sutphin, RM | 1 |
| Colon, J | 1 |
| Isley, B | 1 |
| Bhakat, KK | 1 |
| Srivenugopal, KS | 1 |
| Kalkunte, SS | 1 |
| Baker, CH | 1 |
| Maze, R | 1 |
| Kurpad, C | 1 |
| Pegg, AE | 1 |
| Erickson, LC | 1 |
| Williams, DA | 1 |
2 other studies available for o(6)-benzylguanine and Carcinoma
| Article | Year |
|---|---|
Blockade of MGMT expression by O6 benzyl guanine leads to inhibition of pancreatic cancer growth and induction of apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Proliferation; DNA Modification Methylase | 2009 |
Retroviral-mediated expression of the P140A, but not P140A/G156A, mutant form of O6-methylguanine DNA methyltransferase protects hematopoietic cells against O6-benzylguanine sensitization to chloroethylnitrosourea treatment.
Topics: Animals; Antineoplastic Agents; Carcinoma; Ethylnitrosourea; Female; Genetic Vectors; Guanine; Hemat | 1999 |