o(6)-benzylguanine has been researched along with Anaplastic Astrocytoma in 2 studies
O(6)-benzylguanine: a suicide inhibitor of O(6)-methylguanine-DNA methyltransferase activity
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-three patients were treated (22 with glioblastoma multiforme and one with anaplastic astrocytoma)." | 2.69 | Phase I trial of carmustine plus O6-benzylguanine for patients with recurrent or progressive malignant glioma. ( Ashley, DM; Bigner, DD; Cokgor, I; Colvin, OM; Dolan, ME; Ewesuedo, RB; Friedman, AH; Friedman, HS; Garcia-Turner, AM; Haglund, MM; Herndon, JE; Long, L; McLendon, RE; Moschel, RC; Pegg, AE; Pluda, J; Provenzale, JM; Quinn, JA; Rich, JN; Sampson, J; Stewart, ES; Tourt-Uhlig, S, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wedge, SR | 1 |
| Newlands, ES | 1 |
| Friedman, HS | 1 |
| Pluda, J | 1 |
| Quinn, JA | 1 |
| Ewesuedo, RB | 1 |
| Long, L | 1 |
| Friedman, AH | 1 |
| Cokgor, I | 1 |
| Colvin, OM | 1 |
| Haglund, MM | 1 |
| Ashley, DM | 1 |
| Rich, JN | 1 |
| Sampson, J | 1 |
| Pegg, AE | 1 |
| Moschel, RC | 1 |
| McLendon, RE | 1 |
| Provenzale, JM | 1 |
| Stewart, ES | 1 |
| Tourt-Uhlig, S | 1 |
| Garcia-Turner, AM | 1 |
| Herndon, JE | 1 |
| Bigner, DD | 1 |
| Dolan, ME | 1 |
1 trial available for o(6)-benzylguanine and Anaplastic Astrocytoma
| Article | Year |
|---|---|
Phase I trial of carmustine plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Carmustine; Central Nervous Syst | 2000 |
1 other study available for o(6)-benzylguanine and Anaplastic Astrocytoma
| Article | Year |
|---|---|
O6-benzylguanine enhances the sensitivity of a glioma xenograft with low O6-alkylguanine-DNA alkyltransferase activity to temozolomide and BCNU.
Topics: Animals; Antineoplastic Agents; Astrocytoma; Body Weight; Carmustine; Cell Division; Cell Line; Daca | 1996 |