o(6)-benzyl-2'-deoxyguanosine has been researched along with Brain Neoplasms in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berger, MS; Chang, SM; Davis, RL; Fink, KL; Hess, KR; Kokkinakis, DM; Mehta, MP; Prados, MD; Robins, HI; Schiff, D; Schold, SC | 1 |
| Bacolod, MD; Bigner, DD; Bullock, NS; Colvin, OM; Dolan, ME; Fang, Q; Friedman, HS; Johnson, SP; Modrich, P; Moschel, RC; Pegg, AE | 1 |
| Kokkinakis, DM; Moschel, RC; Pegg, AE; Rudy, JL; Schold, SC | 1 |
| Chen, ZP; Huang, Q; Pan, J; Sun, ZF; Wang, AD; Zhou, LY | 1 |
1 trial(s) available for o(6)-benzyl-2'-deoxyguanosine and Brain Neoplasms
| Article | Year |
|---|---|
O6-benzylguanine suppression of O6-alkylguanine-DNA alkyltransferase in anaplastic gliomas.
Topics: Adult; Aged; Alkyl and Aryl Transferases; Astrocytoma; Brain Neoplasms; Deoxyguanosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Female; Glioblastoma; Humans; Injections, Intravenous; Logistic Models; Male; Middle Aged | 2004 |
3 other study(ies) available for o(6)-benzyl-2'-deoxyguanosine and Brain Neoplasms
| Article | Year |
|---|---|
Brain tumor cell lines resistant to O6-benzylguanine/1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy have O6-alkylguanine-DNA alkyltransferase mutations.
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Line, Tumor; Deoxyguanosine; Drug Resistance, Neoplasm; Guanine; Humans; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Polymorphism, Genetic | 2004 |
Treatment of human brain tumor xenografts with O6-benzyl-2'-deoxyguanosine and BCNU.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cell Death; Deoxyguanosine; Humans; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; O(6)-Methylguanine-DNA Methyltransferase; Transplantation, Heterologous | 1996 |
Antitumor efficacy of SarCNU in a human glioma xenograft model expressing both MGMT and extraneuronal monoamine transporter.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Carrier Proteins; Cell Line; Deoxyguanosine; Female; Glioma; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; O(6)-Methylguanine-DNA Methyltransferase; Organic Cation Transport Proteins; Transplantation, Heterologous | 2001 |