nystatin-a1 and Ulcer

The goal of reducing oral complications during chemotherapy and bone marrow transplantation has received attention at several centers. The current randomized study of 86 adults with leukemia treated with chemotherapy or bone marrow transplantation assessed the potential role of chlorhexidine, nystatin, and saline solution rinses to reduce the findings of oral mucositis, gingivitis, and oral infection. The results of this study did not show a reduction in mucositis with the use of these rinses. However, potential bacterial and fungal pathogens were identified less frequently in the patients using chlorhexidine rinse.

Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bacteremia; Bacteria; Bone Marrow Transplantation; Candidiasis, Oral; Chlorhexidine; Drug Combinations; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Mouth Diseases; Mouthwashes; Nystatin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis; Ulcer; Whole-Body Irradiation

Topics: Administration, Topical; Aged; Drug Combinations; Female; Gramicidin; Humans; Injections; Lichen Planus; Methylprednisolone; Neomycin; Nystatin; Tongue Diseases; Triamcinolone Acetonide; Ulcer

In a 20-month period, generalized chronic cutaneous candidiasis developed in 3 performing bottle-nosed dolphins kept in an indoor pool. Extensive esophagogastric ulcerations were observed in 2 of the dolphins, each of which died, presumably because of these lesions. The 3rd dolphin died during a surgical procedure and did not have any esophagogastric ulcerations. Candida albicans was the only organism isolated from skin lesions but was not isolated from adjacent normal skin of dolphins. Treatment with antifungal drugs was unsuccessful. Subsequently, immunopotentiating treatment with levamisole phosphate resulted in formation of granulation tissue and healing of the skin lesions.

Topics: Animals; Animals, Zoo; Candidiasis, Cutaneous; Dolphins; Esophageal Diseases; Esophagus; Female; Levamisole; Male; Nystatin; Skin; Stomach; Stomach Ulcer; Ulcer

Topics: Administration, Topical; Adolescent; Anti-Inflammatory Agents; Barium Sulfate; Biopsy; Crohn Disease; Epithelium; Humans; Hydrocortisone; Male; Mouth Diseases; Mouth Mucosa; Mouthwashes; Nystatin; Oral Manifestations; Physical Examination; Prednisone; Radiography; Sulfasalazine; Tetracycline; Ulcer

Topics: Adult; Barium; Colitis, Ulcerative; Esophagitis; Esophagoscopy; Humans; Male; Nystatin; Prednisolone; Sigmoidoscopy; Ulcer

Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Cornea; Corneal Ulcer; Eye Infections, Fungal; Nystatin; Ulcer