nystatin-a1 and Laryngeal-Diseases

Upper airway obstruction is always a serious condition. In patients who have previously been irradiated for a laryngeal malignancy, it normally implies either residual or recurrent disease. We report a case of stridor due to invasive laryngeal candidiasis in a patient who had undergone radiotherapy for a T1a N0 squamous cell carcinoma of the glottis eight months earlier. Extensive investigation failed to identify recurrence of disease and the patient responded to prolonged topical antifungal therapy. Infection with Candida species is most frequently found in debilitated or immunocompromised patients. Although cases of upper airway obstruction in children secondary to idiopathic laryngeal candidiasis have been reported, to our knowledge no such presentation has been described in adults. This report highlights the difficulty of diagnosis and treatment. Familiarity with candidal infection is important for early diagnosis and appropriate treatment.

Topics: Administration, Topical; Aged; Antifungal Agents; Candidiasis; Carcinoma, Squamous Cell; Humans; Laryngeal Diseases; Laryngeal Neoplasms; Laryngoscopy; Male; Nystatin; Radiotherapy; Respiratory Sounds

Candidiasis of the larynx is rare and often related to immunocompromised hosts. We here report a case of laryngeal candidiasis in an immunocompetent infant. The diagnosis was obtained by direct fibre-optic laryngoscopy with specimens submitted for culture. He received anti-fungal medication and was quite well at 1-year follow up. The pertinent literature is also reviewed.

Topics: Administration, Oral; Antifungal Agents; Candidiasis; Drug Therapy, Combination; Fluconazole; Humans; Infant; Laryngeal Diseases; Laryngoscopy; Larynx; Male; Nystatin

Topics: Amphotericin B; Chromoblastomycosis; Diagnosis, Differential; Fungi; Humans; Laryngeal Diseases; Male; Middle Aged; Nystatin

Topics: Amphotericin B; Aspergillosis; Humans; Laryngeal Diseases; Male; Middle Aged; Nystatin; Respiratory Tract Infections

Topics: Adult; Biopsy; Candidiasis; Diagnosis, Differential; Humans; Keratosis; Laryngeal Diseases; Laryngeal Neoplasms; Laryngoscopy; Larynx; Male; Nystatin