nystatin-a1 and Gram-Positive-Bacterial-Infections

nystatin-a1 has been researched along with Gram-Positive-Bacterial-Infections* in 1 studies

Other Studies

1 other study(ies) available for nystatin-a1 and Gram-Positive-Bacterial-Infections

ArticleYear
Microwave assisted synthesis and antimicrobial evaluation of new fused pyran derivatives bearing 2-morpholinoquinoline nucleus.
    Bioorganic & medicinal chemistry letters, 2011, Oct-15, Volume: 21, Issue:20

    A new series of fused pyran derivatives 5a-x bearing 2-morpholinoquinoline nucleus has been synthesized under microwave irradiation by a reaction of 2-morpholinoquinoline-3-carbaldehyde 2a-c, malononitrile 3 and compounds 4a-h in presence of NaOH as basic catalyst. All the compounds were screened against three Gram positive bacteria (Streptococcus pneumoniae, Clostridium tetani, Bacillus subtilis), three Gram negative bacteria (Salmonella typhi, Vibrio cholerae, Escherichia coli) and two fungi (Aspergillus fumigatus, Candida albicans) using broth microdilution MIC (Minimum Inhibitory Concentration) method. Of the compounds studied, compounds 5b, 5f, 5k, 5m, 5q, 5s and 5v have found to be most efficient members of the series.

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Candida albicans; Fungi; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Microwaves; Mycoses; Pyrans; Quinolines

2011